scholarly journals Specific donor Vβ-associated CD4+ T-cell responses correlate with severe acute graft-versus-host disease directed to multiple minor histocompatibility antigens

2004 ◽  
Vol 10 (2) ◽  
pp. 91-105 ◽  
Author(s):  
Stephen C. Jones ◽  
Thea M. Friedman ◽  
George F. Murphy ◽  
Robert Korngold
Keyword(s):  
T Cell ◽  
Graft Versus Host Disease ◽  
T Cell Responses ◽  
Cd4 T Cell ◽  
Histocompatibility Antigens ◽  
Host Disease ◽  
Minor Histocompatibility Antigens ◽  
Graft Versus Host ◽  
Cell Responses ◽  
Acute Graft

Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease

Blood ◽  
2014 ◽  
Vol 123 (2) ◽  
pp. 290-299 ◽  
Author(s):  
Marie-Charlotte Brüggen ◽  
Irene Klein ◽  
Hildegard Greinix ◽  
Wolfgang Bauer ◽  
Zoya Kuzmina ◽  
...  
Keyword(s):  
T Cell ◽  
Graft Versus Host Disease ◽  
T Cell Responses ◽  
Host Disease ◽  
Graft Versus Host ◽  
Cell Responses ◽  
Key Points ◽  
Cell Patterns

Key Points Distinct T-cell patterns characterize the acute and chronic forms of cutaneous GVHD. Increased TSLP expression is an indicator of acute cutaneous GVHD development.

scholarly journals MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice

Blood ◽  
2015 ◽  
Vol 126 (11) ◽  
pp. 1314-1323 ◽  
Author(s):  
Yongxia Wu ◽  
Jessica Heinrichs ◽  
David Bastian ◽  
Jianing Fu ◽  
Hung Nguyen ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
Graft Versus Host Disease ◽  
T Cell Responses ◽  
Host Disease ◽  
Graft Versus Host ◽  
Cell Responses ◽  
Key Points ◽  
Leukemia Relapse

Key Points miR-17-92 is required for T cells to mediate GVHD but not the GVL effect. Targeting miR-17-92 with antagomirs efficiently alleviates GVHD.

scholarly journals Hsp90 inhibition ameliorates CD4+T cell-mediated acute Graft versus Host disease in mice

2016 ◽  
Vol 4 (4) ◽  
pp. 463-473
Author(s):  
Carsten Berges ◽  
Thomas Kerkau ◽  
Sandra Werner ◽  
Nelli Wolf ◽  
Nadine Winter ◽  
...  
Keyword(s):  
T Cell ◽  
Graft Versus Host Disease ◽  
Cd4 T Cell ◽  
Hsp90 Inhibition ◽  
Host Disease ◽  
Graft Versus Host ◽  
Acute Graft
Sign in / Sign up

Export Citation Format

Share Document