Time decay of object, place and temporal order memory in a paradigm assessing simultaneously episodic-like memory components in mice

2015 ◽  
Vol 286 ◽  
pp. 80-84 ◽  
Author(s):  
Hassina Belblidia ◽  
Abdelmalek Abdelouadoud ◽  
Christelle Jozet-Alves ◽  
Hélène Dumas ◽  
Thomas Freret ◽  
...  
2013 ◽  
Vol 106 ◽  
pp. 268-273 ◽  
Author(s):  
Stéphanie Lejeune ◽  
Nathalie Dourmap ◽  
Marie-Pascale Martres ◽  
Bruno Giros ◽  
Valérie Daugé ◽  
...  

2009 ◽  
Vol 15 (5) ◽  
pp. 662-670 ◽  
Author(s):  
EVA PIROGOVSKY ◽  
JODY GOLDSTEIN ◽  
GUERRY PEAVY ◽  
MARK W. JACOBSON ◽  
JODY COREY-BLOOM ◽  
...  

AbstractThe current study examined temporal order memory in preclinical Huntington’s disease (pre-HD). Participants were separated into less than 5 years (pre-HD near) and more than 5 years (pre-HD far) from estimated age of clinical diagnosis. Participants completed a temporal order memory task on a computerized radial eight-arm maze. On the study phase of each trial, participants viewed a random sequence of circles appearing one at a time at the end of each arm. On the choice phase, participants viewed two circles at the end of the study phase arms and chose the circle occurring earliest in the sequence. The task involved manipulations of the temporal lag, defined as the number of arms occurring in the sample phase sequence between the two choice phase arms. Research suggests that there is more interference for temporally proximal stimuli relative to temporally distal stimuli. There were no significant differences between the pre-HD far group and controls on the temporal order memory task. The pre-HD near group demonstrated significant impairments relative to the other groups on closer temporal lags, but were normal on the furthest temporal lag. Therefore, temporal order memory declines with increased temporal interference in pre-HD close to estimated diagnosis of HD. (JINS, 2009, 15, 662–670.)


Peptides ◽  
2010 ◽  
Vol 31 (1) ◽  
pp. 108-115 ◽  
Author(s):  
S. Schäble ◽  
J.P. Huston ◽  
M.L. Brandao ◽  
E. Dere ◽  
M.A. de Souza Silva

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