Endothelial stress induces the release of vitamin D-binding protein, a novel growth factor

2005 ◽  
Vol 338 (3) ◽  
pp. 1374-1382 ◽  
Author(s):  
Marc-André Raymond ◽  
Anik Désormeaux ◽  
Andrée Labelle ◽  
Mathilde Soulez ◽  
Gilles Soulez ◽  
...  
Keyword(s):  
Vitamin D ◽  
Growth Factor ◽  
Binding Protein ◽  
Protein A ◽  
Vitamin D Binding Protein ◽  
Endothelial Stress

Vitamin D binding protein, a new nutritional marker in cystic fibrosis patients

2008 ◽  
Vol 46 (3) ◽  
Author(s):  
Marijn M. Speeckaert ◽  
Charline Wehlou ◽  
Sara Vandewalle ◽  
Youri E. Taes ◽  
Eddy Robberecht ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Vitamin D ◽  
Binding Protein ◽  
Protein A ◽  
Vitamin D Binding Protein ◽  
Nutritional Marker

scholarly journals Vitamin D Binding Protein: A Historic Overview

2020 ◽  
Vol 10 ◽  
Author(s):  
Roger Bouillon ◽  
Frans Schuit ◽  
Leen Antonio ◽  
Fraydoon Rastinejad
Keyword(s):  
Vitamin D ◽  
Binding Protein ◽  
Protein A ◽  
Vitamin D Binding Protein

scholarly journals Is Vitamin D Binding Protein a Novel Predictor of Labour?

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e76490 ◽  
Author(s):  
Stella Liong ◽  
Megan K. W. Di Quinzio ◽  
Gabrielle Fleming ◽  
Michael Permezel ◽  
Harry M. Georgiou
Keyword(s):  
Vitamin D ◽  
Binding Protein ◽  
Protein A ◽  
Vitamin D Binding Protein

Recommendations on the measurement and the clinical use of vitamin D metabolites and vitamin D binding protein – A position paper from the IFCC Committee on bone metabolism

2021 ◽  
Vol 517 ◽  
pp. 171-197
Author(s):  
Konstantinos Makris ◽  
Harjit P Bhattoa ◽  
Etienne Cavalier ◽  
Karen Phinney ◽  
Christopher T. Sempos ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Metabolism ◽  
Binding Protein ◽  
Protein A ◽  
Position Paper ◽  
Vitamin D Metabolites ◽  
Clinical Use ◽  
Vitamin D Binding Protein

scholarly journals Vitamin D Binding Protein: A Fidelity Molecule in Spectra of Diseases

2021 ◽  
Author(s):  
Bhuneshwar Yadav ◽  
Kurpad Nagraj Shashidhar ◽  
Harish Reddy ◽  
R Sai Deepika
Keyword(s):  
Vitamin D ◽  
Bone Development ◽  
Binding Protein ◽  
Protein A ◽  
Circulatory System ◽  
Antitumoral Activity ◽  
Vitamin D Metabolites ◽  
Vitamin D Binding Protein ◽  
Carrier Molecule ◽  
Transport Control

Vitamin D Binding Protein (VDBP), also well-known as Gc-globulin, is a plasma protein which acts as a carrier molecule for vitamin D and its metabolites. This multifunctional glycoprotein is a member of the albumin superfamily of binding proteins. It is predominantly synthesized as a single long chain glycoprotein in the liver. VDBP helps in vitamin D metabolites transport, control bone development, binds actin monomers and fatty acids and prevents their polymerization; which might be harmful in circulatory system. A less defined role in modulating immune and inflammatory response is also known. VDBP plays an important role in protection of microcirculation, inflammation, infection and also known to have antiviral and antitumoral activity. Recent studies documented its use as a early marker for diagnosis of chronic kidney disease. This review discusses the multifunctional characters of VDBP in spectra of diseases with emphasis on its use as marker for diabetic nephropathy.

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