Electrochemical immunosensor for detecting carcinoembryonic antigen using hollow Pt nanospheres-labeled multiple enzyme-linked antibodies as labels for signal amplification

2011 ◽  
Vol 56 (3) ◽  
pp. 116-124 ◽  
Author(s):  
Hongchuan Yang ◽  
Ruo Yuan ◽  
Yaqin Chai ◽  
Li Mao ◽  
Huilan Su ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Signal Amplification ◽  
Electrochemical Immunosensor

A novel electrochemical immunoassay for carcinoembryonic antigen based on glucose oxidase-encapsulated nanogold hollow spheres with a pH meter readout

The Analyst ◽  
2018 ◽  
Vol 143 (21) ◽  
pp. 5271-5277 ◽  
Author(s):  
Yu Jiang ◽  
Zhiying Su ◽  
Jian Zhang ◽  
Meijiao Cai ◽  
Lili Wu
Keyword(s):  
Carcinoembryonic Antigen ◽  
Glucose Oxidase ◽  
Signal Amplification ◽  
Hollow Spheres ◽  
Electrochemical Immunosensor ◽  
Hollow Microspheres ◽  
Electrochemical Immunoassay

A portable electrochemical immunosensor was designed for the detection of CEA on a pH meter by using glucose oxidase-encapsulated gold hollow microspheres for signal amplification.

A novel electrochemical immunosensor based on CoS2 for early screening of tumor marker carcinoembryonic antigen

2020 ◽  
Vol 44 (8) ◽  
pp. 3524-3532 ◽  
Author(s):  
Chulei Zhao ◽  
Chaoyun Ma ◽  
Mei Wu ◽  
Wenjun Li ◽  
Yiju Song ◽  
...  
Keyword(s):  
Tumor Marker ◽  
Carcinoembryonic Antigen ◽  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Biometric Recognition ◽  
Early Screening

In this work, PANI–HRP nanoparticles integrate biometric recognition and signal amplification functions in one body, which can be converted to each other without consuming the material itself.

Construction of electrochemical immunosensor based on redox hydrogel for ultrasensitive detection of carcinoembryonic antigen

2021 ◽  
Author(s):  
Xiangrong Huang ◽  
Na Wu ◽  
Wenxiu Liu ◽  
Yazhuo Shang ◽  
Honglai Liu ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Carcinoembryonic Antigen ◽  
Electrochemical Detection ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free

In this work, a novel redox hydrogel was proposed for ultrasensitive label-free electrochemical detection of carcinoembryonic antigen (CEA). The redox hydrogel composed by cellulose nanocrystalline (CNC), methylene blue (MB), multi-walled...

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

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