Fabrication of Electrochemical Immunosensor Using Gold Nanoclusters as Signal Amplification Labels

2013 ◽  
Vol 41 (5) ◽  
pp. 658
Author(s):  
Hong-Ying LIU ◽  
Jun-Jie ZHU
Keyword(s):  
Signal Amplification ◽  
Gold Nanoclusters ◽  
Electrochemical Immunosensor

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

A novel electrochemical immunosensor based on dual signal amplification of gold nanoparticles and telomerase extension reaction

2014 ◽  
Vol 6 (7) ◽  
pp. 2221-2226 ◽  
Author(s):  
Xiao-Yan Li ◽  
Zi Yi ◽  
Hao Tang ◽  
Xia Chu ◽  
Ru-Qin Yu
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Highly Sensitive ◽  
Dual Signal Amplification

Highly sensitive electrochemical immune analysis was achieved based on dual signal amplification of AuNPs and telomerase extension reaction.

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