Scale-up of docosahexaenoic acid production in fed-batch fermentation by Schizochytrium sp. based on volumetric oxygen-transfer coefficient

2013 ◽  
Vol 77 ◽  
pp. 82-87 ◽  
Author(s):  
Liang Qu ◽  
Lu-Jing Ren ◽  
He Huang
2003 ◽  
Vol 46 (3) ◽  
pp. 455-459 ◽  
Author(s):  
Georgina L. Michelena ◽  
Aidín Martínez ◽  
Antonio Bell ◽  
Emilia Carrera ◽  
Roxana Valencia

Fed batch fermentation was carried out for the dextransucrase enzyme production from Leuconostoc mesenteroides and the production was scale-up using oxygen transfer criteriuom. It was found that in 5 L vessel fermentation capacity, the best agitation speed was 225 min-1 and aeration rate was 0.15 vvm, obtaining dextransucrase activity of 127 DSU/mL.. The maximum enzyme production velocity coincide with the maximum growth velocity between 6 and 7 h of fermentation, which confirmed that dextransucrase production was associated with microbial growth. High enzyme yields were achieved during scale up based on oxygen transfer rate.


2010 ◽  
Vol 150 ◽  
pp. 320-320 ◽  
Author(s):  
Noelia Rodríguez ◽  
Jose Manuel Salgado ◽  
Belén Max ◽  
Sandra Cortés ◽  
Jose Manuel Domínguez

1991 ◽  
Vol 36 (3) ◽  
Author(s):  
Takaomi Ito ◽  
Hiroyuki Sota ◽  
Hiroyuki Honda ◽  
Kazuyuki Shimizu ◽  
Takeshi Kobayashi

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