scholarly journals Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: Scaffold design and its performance when seeded with goat bone marrow stromal cells

Biomaterials ◽  
2006 ◽  
Vol 27 (36) ◽  
pp. 6123-6137 ◽  
Author(s):  
Joaquim M. Oliveira ◽  
Márcia T. Rodrigues ◽  
Simone S. Silva ◽  
Patrícia B. Malafaya ◽  
Manuela E. Gomes ◽  
...  
Soft Matter ◽  
2015 ◽  
Vol 11 (38) ◽  
pp. 7648-7655 ◽  
Author(s):  
Paul Lee ◽  
Katelyn Tran ◽  
Gan Zhou ◽  
Asheesh Bedi ◽  
Namdev B. Shelke ◽  
...  

A biphasic micro and nanostructured scaffold with hydroxyapatite and extracellular matrix components was created for the regeneration of osteochondral tissue. Material cues of the biphasic scaffold supported differentiation of bone marrow stromal cells in both osteogenic and chondrogenic lineages.


2011 ◽  
Vol 26 (8) ◽  
pp. 1035-1049 ◽  
Author(s):  
Federico Foschi ◽  
Enrico Conserva ◽  
Paolo Pera ◽  
Barbara Canciani ◽  
Ranieri Cancedda ◽  
...  

2009 ◽  
Vol 15 (10) ◽  
pp. 3109-3117 ◽  
Author(s):  
Floor van Eijk ◽  
Daniel B.F. Saris ◽  
Natalja E. Fedorovich ◽  
Moyo C. Kruyt ◽  
W. Jaap Willems ◽  
...  

2008 ◽  
Vol 368-372 ◽  
pp. 1235-1237 ◽  
Author(s):  
Lei Liu ◽  
Run Liang Chen ◽  
Yun Feng Lin ◽  
Wei Dong Tian ◽  
Sheng Wei Li

Hydroxyapatite-tricalcium phosphate (HA-TCP) is a new kind of material which shows good biocompatibility, biological degradability, and porosity. This study aimed to determine the effectiveness of HA-TCP as a bone tissue engineering scaffold. In this study, critical size cranial defects were reconstructed with compounds of autogenous bone marrow stromal cells (BMSCs) and HA-TCP. The resulting grafts were examined by X-ray, histological examination, semi-quantitative analysis of osteogenesis, immunochemical examination (collagen type I and III), scanning electron microscopy and transmission electron microscopy. The results showed that HA-TCP is a good bone tissue engineering scaffold and BMSCs/HA-TCP is a promising technique for reconstruction of bone defects.


2006 ◽  
Vol 1 (5) ◽  
pp. 685-692 ◽  
Author(s):  
Simon Tilley ◽  
Benjamin JRF Bolland ◽  
Kris Partridge ◽  
Andrew MR New ◽  
Jeremy M Latham ◽  
...  

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