Bioresorption behavior of tetracalcium phosphate-derived calcium phosphate cement implanted in femur of rabbits

Biomaterials ◽  
2008 ◽  
Vol 29 (8) ◽  
pp. 984-993 ◽  
Author(s):  
Chih-Hung Tsai ◽  
Ruey-Mo Lin ◽  
Chien-Ping Ju ◽  
Jiin-Huey Chern Lin
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Tetracalcium Phosphate

scholarly journals Polymeric-Calcium Phosphate Cement Composites-Material Properties:In VitroandIn VivoInvestigations

2010 ◽  
Vol 2010 ◽  
pp. 1-14 ◽  
Author(s):  
Rania M. Khashaba ◽  
Mervet M. Moussa ◽  
Donald J. Mettenburg ◽  
Frederick A. Rueggeberg ◽  
Norman B. Chutkan ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Setting Time ◽  
Cement Composites ◽  
Tetracalcium Phosphate ◽  
Methyl Vinyl Ether ◽  
Orthopedic Applications ◽  
Hydroxyapatite Cement

New polymeric calcium phosphate cement composites (CPCs) were developed. Cement powder consisting of 60 wt% tetracalcium phosphate, 30 wt% dicalcium phosphate dihydrate, and 10 wt% tricalcium phosphate was combined with either 35% w/w poly methyl vinyl ether maleic acid or polyacrylic acid to obtain CPC-1 and CPC-2. The setting time and compressive and diametral tensile strength of the CPCs were evaluated and compared with that of a commercial hydroxyapatite cement.In vitrocytotoxicity andin vivobiocompatibility of the two CPCs and hydroxyapatite cement were assessed. The setting time of the cements was 5–15 min. CPC-1 and CPC-2 showed significantly higher compressive and diametral strength values compared to hydroxyapatite cement. CPC-1 and CPC-2 were equivalent to Teflon controls after 1 week. CPC-1, CPC-2, and hydroxyapatite cement elicited a moderate to intense inflammatory reaction at 7 days which decreased over time. CPC-1 and CPC-2 show promise for orthopedic applications.

Preparation of Tetracalcium Phosphate and the Effect on the Properties of Calcium Phosphate Cement

2009 ◽  
Vol 610-613 ◽  
pp. 1356-1359 ◽  
Author(s):  
Dan Kai ◽  
Hong Song Fan ◽  
Dong Xiao Li ◽  
Xiang Dong Zhu ◽  
Xing Dong Zhang
Keyword(s):  
Particle Size ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Preparation Method ◽  
Precipitation Method ◽  
Improve Performance ◽  
Solid Reaction ◽  
Tetracalcium Phosphate ◽  
Fast Cooling ◽  
Co Precipitation

In the present study, three types of tetracalcium phosphate (TTCP) were prepared by solid-solid reaction or co-precipitation method and by different cooling modes. The effect of TTCP on the performance of calcium phosphate cement (CPC) was investigated. The result showed that the characteristic of TTCP varied with preparation method and played an important role in CPC performance. A solid-solid reacted TTCP yielded smaller particle size and resulted in bad workability and mechanical strength of CPC. The fast cooling of sintering TTCP by liquid nitrogen could avoid the decomposition of TTCP and make pure TTCP. TTCP prepared by wet-precipitation could improve performance of CPC and was promising to optimization of CPC.

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