γ-Radiation-induced changes in structure and properties of tetracalcium phosphate and its derived calcium phosphate cement

2006 ◽  
Vol 80B (1) ◽  
pp. 244-252 ◽  
Author(s):  
Chih-Hung Tsai ◽  
Jiin-Huey Chern Lin ◽  
Chien-Ping Ju
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Structure And Properties ◽  
Tetracalcium Phosphate ◽  
Γ Radiation ◽  
Radiation Induced ◽  
Induced Changes

Bioresorption behavior of tetracalcium phosphate-derived calcium phosphate cement implanted in femur of rabbits

Biomaterials ◽  
2008 ◽  
Vol 29 (8) ◽  
pp. 984-993 ◽  
Author(s):  
Chih-Hung Tsai ◽  
Ruey-Mo Lin ◽  
Chien-Ping Ju ◽  
Jiin-Huey Chern Lin
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Tetracalcium Phosphate

scholarly journals Polymeric-Calcium Phosphate Cement Composites-Material Properties:In VitroandIn VivoInvestigations

2010 ◽  
Vol 2010 ◽  
pp. 1-14 ◽  
Author(s):  
Rania M. Khashaba ◽  
Mervet M. Moussa ◽  
Donald J. Mettenburg ◽  
Frederick A. Rueggeberg ◽  
Norman B. Chutkan ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Setting Time ◽  
Cement Composites ◽  
Tetracalcium Phosphate ◽  
Methyl Vinyl Ether ◽  
Orthopedic Applications ◽  
Hydroxyapatite Cement

New polymeric calcium phosphate cement composites (CPCs) were developed. Cement powder consisting of 60 wt% tetracalcium phosphate, 30 wt% dicalcium phosphate dihydrate, and 10 wt% tricalcium phosphate was combined with either 35% w/w poly methyl vinyl ether maleic acid or polyacrylic acid to obtain CPC-1 and CPC-2. The setting time and compressive and diametral tensile strength of the CPCs were evaluated and compared with that of a commercial hydroxyapatite cement.In vitrocytotoxicity andin vivobiocompatibility of the two CPCs and hydroxyapatite cement were assessed. The setting time of the cements was 5–15 min. CPC-1 and CPC-2 showed significantly higher compressive and diametral strength values compared to hydroxyapatite cement. CPC-1 and CPC-2 were equivalent to Teflon controls after 1 week. CPC-1, CPC-2, and hydroxyapatite cement elicited a moderate to intense inflammatory reaction at 7 days which decreased over time. CPC-1 and CPC-2 show promise for orthopedic applications.

Preparation of Tetracalcium Phosphate and the Effect on the Properties of Calcium Phosphate Cement

2009 ◽  
Vol 610-613 ◽  
pp. 1356-1359 ◽  
Author(s):  
Dan Kai ◽  
Hong Song Fan ◽  
Dong Xiao Li ◽  
Xiang Dong Zhu ◽  
Xing Dong Zhang
Keyword(s):  
Particle Size ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Preparation Method ◽  
Precipitation Method ◽  
Improve Performance ◽  
Solid Reaction ◽  
Tetracalcium Phosphate ◽  
Fast Cooling ◽  
Co Precipitation

In the present study, three types of tetracalcium phosphate (TTCP) were prepared by solid-solid reaction or co-precipitation method and by different cooling modes. The effect of TTCP on the performance of calcium phosphate cement (CPC) was investigated. The result showed that the characteristic of TTCP varied with preparation method and played an important role in CPC performance. A solid-solid reacted TTCP yielded smaller particle size and resulted in bad workability and mechanical strength of CPC. The fast cooling of sintering TTCP by liquid nitrogen could avoid the decomposition of TTCP and make pure TTCP. TTCP prepared by wet-precipitation could improve performance of CPC and was promising to optimization of CPC.

Studies on the Metabolism of Nuclear Basic Proteins After Radiation In Vitro

1971 ◽  
Vol 49 (4) ◽  
pp. 456-462 ◽  
Author(s):  
Mira Ghosh
Keyword(s):  
Protein Synthesis ◽  
Amino Acid ◽  
Cell Permeability ◽  
Γ Radiation ◽  
Basic Proteins ◽  
Two Factors ◽  
Radiation Induced ◽  
Rabbit Lymphocytes ◽  
Induced Changes

Exposure of isolated rabbit lymphocytes to 1000 R γ-radiation results in an increased rate of incorporation of amino acids-14C into cellular proteins during the first hour after irradiation. Fractionation of the proteins showed that the synthesis of basic proteins extracted from the nucleus was most affected. Two factors contributed to this apparent stimulation of protein synthesis by irradiation: (a) a transient increase in the amount of amino acid-14C available for protein synthesis in the cell; and (b) an increase in concentration of sodium ions in the cell. It is suggested that much of the observed increase in amino acid incorporation after irradiation of the lymphocytes is caused by radiation-induced changes in cell permeability.

scholarly journals Analysis of a lectin microarray identifies altered sialylation of mouse serum glycoproteins induced by whole-body radiation exposure

2018 ◽  
Vol 60 (2) ◽  
pp. 189-196 ◽  
Author(s):  
Daisuke Iizuka ◽  
Shunsuke Izumi ◽  
Fumio Suzuki ◽  
Kenji Kamiya
Keyword(s):  
Sialic Acid ◽  
Radiation Exposure ◽  
Initial Response ◽  
Sialic Acids ◽  
Whole Body ◽  
Mouse Serum ◽  
Global Changes ◽  
Γ Radiation ◽  
Radiation Induced ◽  
Induced Changes

AbstractMicroarrays containing 45 different lectins were analyzed to identify global changes in the glycosylation of serum glycoproteins from mice exposed to whole-body γ-radiation. The results showed that radiation exposure increased and decreased the relative amounts of α-2,3- and α-2,6-sialic acids, respectively. The expression of α-2,3- and α-2,6-sialyltransferase genes in the liver was analyzed to determine whether changes in their expression were responsible for the sialic acid changes. The increase in α-2,3-sialic acid correlated with St3gal5 upregulation after radiation exposure; however, a decrease in St6gal1 expression was not observed. Analysis of a PCR array of genes expressed in irradiated mouse livers revealed that irradiation did not alter the expression of most of the included genes. These results suggest that glycomic screening of serum glycoproteins using lectin microarrays can be a powerful tool for identifying radiation-induced changes in the post-translational addition of sugar moieties to proteins. In addition, the results indicate that altered sialylation of glycoproteins may be an initial response to acute radiation exposure.

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