RBC membrane camouflaged prussian blue nanoparticles for gamabutolin loading and combined chemo/photothermal therapy of breast cancer

Biomaterials ◽  
2019 ◽  
Vol 217 ◽  
pp. 119301 ◽  
Author(s):  
Bin Liu ◽  
Wenmiao Wang ◽  
Jialong Fan ◽  
Ying Long ◽  
Feng Xiao ◽  
...  
RSC Advances ◽  
2015 ◽  
Vol 5 (36) ◽  
pp. 28401-28409 ◽  
Author(s):  
Peng Xue ◽  
Jingnan Bao ◽  
Yafeng Wu ◽  
Yilei Zhang ◽  
Yuejun Kang

Multifunctional magnetic nanoparticles based on Fe3O4 nanocore and Prussian blue nanoshell for combined enzyme-responsive drug release and photothermal therapy.


2014 ◽  
Vol 2 (23) ◽  
pp. 3686-3696 ◽  
Author(s):  
Zhenglin Li ◽  
Yongyi Zeng ◽  
Da Zhang ◽  
Ming Wu ◽  
Lingjie Wu ◽  
...  

MRI-guided photothermal therapy is becoming a more widely accepted minimally invasive technique.


2018 ◽  
Vol 6 (37) ◽  
pp. 5854-5859 ◽  
Author(s):  
Yan Ma ◽  
Huajian Chen ◽  
Baimei Hao ◽  
Junhong Zhou ◽  
Gang He ◽  
...  

A controllable CQ delivery platform consisting of hollow mesoporous Prussian blue nanoparticles and phase changing material was developed here to realize tumor specific autophagy inhibition for enhanced PTT.


2019 ◽  
Vol 9 (1) ◽  
pp. 1900948 ◽  
Author(s):  
Pingbo Shou ◽  
Zhangsen Yu ◽  
Yiting Wu ◽  
Qiang Feng ◽  
Bangyi Zhou ◽  
...  

2022 ◽  
Vol 20 (1) ◽  
Author(s):  
Quan Tao ◽  
Genghan He ◽  
Sheng Ye ◽  
Di Zhang ◽  
Zhide Zhang ◽  
...  

Abstract Background Combining the multimodal imaging and synergistic treatment in one platform can enhance the therapeutic efficacy and diagnosis accuracy. Results In this contribution, innovative Mn-doped Prussian blue nanoparticles (MnPB NPs) were prepared via microemulsion method. MnPB NPs demonstrated excellent T1 and T2 weighted magnetic resonance imaging (MRI) enhancement in vitro and in vivo. The robust absorbance in the near infrared range of MnPB NPs provides high antitumor efficacy for photothermal therapy (PTT) and photoacoustics imaging property. Moreover, with the doping of Mn, MnPB NPs exhibited excellent Fenton reaction activity for chemodynamic therapy (CDT). The favorable trimodal imaging and Fenton reaction enhanced mild temperature photothermal therapy in vitro and in vivo were further confirmed that MnPB NPs have significant positive effectiveness for integration of diagnosis and treatment tumor. Conclusions Overall, this Mn doped Prussian blue nanoplatform with multimodal imaging and chemodynamic/mild temperature photothermal co-therapy provides a reliable tool for tumor treatment. Graphical Abstract


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