Prussian Blue Analogue Derived Co3O4/CuO Nanoparticles as Effective Oxygen Reduction Reaction Catalyst for Magnesium-Air Battery

Developing efficient, durable, and cost-effective non-noble metal catalysts for oxygen reduction reaction (ORR) is necessary to promote the efficiency and performance of Mg-air batteries. Herein, the Co3O4/CuO nanoparticles were synthesized by a low-cost and simple approach using CuCo-based prussian blue analogue (PBA) as precursor of pyrolysis at different calcination temperatures. It was found that the Co3O4/CuO nanoparticles calcined at 600ºC (CCO-600) have relatively small size and superior ORR performance. The onset potential is 0.889 V and the diffusion limiting current density achieves 6.746 mA·cm-2, as well as prominent stability in 0.1 M KOH electrolyte. The electron transfer number of the CCO-600 is 3.89 under alkaline medium, which indicates that the reaction mechanism of ORR is dominated by 4 e process, similar to commercial Pt. The primary Mg-air battery with the CCO-600 as the cathode catalyst has been assembled and possesses better discharge performance than the CuCo-based PBA. The open circuit voltage of CCO-600 arrives at 1.76 V and energy density of 1895.95 mWh/g. This work provides an effective strategy to develop non-noble metal ORR catalyst for the application of metal-air batteries

Mn doped Prussian blue nanoparticles for T1/T2 MR imaging, PA imaging and Fenton reaction enhanced mild temperature photothermal therapy of tumor

Background Combining the multimodal imaging and synergistic treatment in one platform can enhance the therapeutic efficacy and diagnosis accuracy. Results In this contribution, innovative Mn-doped Prussian blue nanoparticles (MnPB NPs) were prepared via microemulsion method. MnPB NPs demonstrated excellent T1 and T2 weighted magnetic resonance imaging (MRI) enhancement in vitro and in vivo. The robust absorbance in the near infrared range of MnPB NPs provides high antitumor efficacy for photothermal therapy (PTT) and photoacoustics imaging property. Moreover, with the doping of Mn, MnPB NPs exhibited excellent Fenton reaction activity for chemodynamic therapy (CDT). The favorable trimodal imaging and Fenton reaction enhanced mild temperature photothermal therapy in vitro and in vivo were further confirmed that MnPB NPs have significant positive effectiveness for integration of diagnosis and treatment tumor. Conclusions Overall, this Mn doped Prussian blue nanoplatform with multimodal imaging and chemodynamic/mild temperature photothermal co-therapy provides a reliable tool for tumor treatment. Graphical Abstract