One-step synthesis of methylene-bridged bis-carbazole and evaluation of its antitumor activity and G-quadruplex DNA binding property

2019 ◽  
Vol 90 ◽  
pp. 103074
Author(s):  
Gang Li ◽  
Haodong Tang ◽  
Chuanfeng Liu ◽  
Xiaoyu Liao ◽  
Sicong Li ◽  
...  
Keyword(s):  
Dna Binding ◽  
Antitumor Activity ◽  
Binding Property ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Dna Binding Property ◽  
One Step

DNA-binding property and antitumor activity of a cyclam bridged dinuclear platinum(II) complex

2009 ◽  
Vol 362 (7) ◽  
pp. 2347-2352 ◽  
Author(s):  
Zihua Xu ◽  
Yangmiao Zhang ◽  
Zuqin Xue ◽  
Xiaoliang Yang ◽  
Ziyi Wu ◽  
...  
Keyword(s):  
Dna Binding ◽  
Antitumor Activity ◽  
Binding Property ◽  
Dinuclear Platinum ◽  
Dna Binding Property

Effect of adenine moiety on DNA binding property of copper(ii)–terpyridine complexes

2008 ◽  
pp. 3054 ◽  
Author(s):  
Qin Jiang ◽  
Zhengyi Wu ◽  
Yangmiao Zhang ◽  
Anna C. G. Hotze ◽  
Michael J. Hannon ◽  
...  
Keyword(s):  
Dna Binding ◽  
Binding Property ◽  
Dna Binding Property

Photophysical, G-quadruplex DNA binding and cytotoxic properties of terpyridine complexes with a naphthalimide ligand

RSC Advances ◽  
2016 ◽  
Vol 6 (43) ◽  
pp. 36923-36931 ◽  
Author(s):  
Zhize Ou ◽  
Yimeng Qian ◽  
Yunyan Gao ◽  
Yunqing Wang ◽  
Guoqiang Yang ◽  
...  
Keyword(s):  
Dna Binding ◽  
A549 Cells ◽  
Nih3t3 Cells ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Nuclear Location

The complex3inhibits A549 cells selectively over non-cancerous NIH3T3 cells, which may correlate with its selective G-quadruplex binding and nuclear location.

New dimeric carbazole–benzimidazole mixed ligands for the stabilization of human telomeric G-quadruplex DNA and as telomerase inhibitors. A remarkable influence of the spacer

2015 ◽  
Vol 13 (30) ◽  
pp. 8335-8348 ◽  
Author(s):  
Basudeb Maji ◽  
Krishan Kumar ◽  
K. Muniyappa ◽  
Santanu Bhattacharya
Keyword(s):  
Dna Binding ◽  
Inhibition Activity ◽  
Telomerase Inhibition ◽  
Quadruplex Dna ◽  
Telomerase Inhibitors ◽  
Mixed Ligands ◽  
G Quadruplex

G-quadruplex DNA binding dimeric ligands and their telomerase inhibition activity are reported.

Synthesis, docking studies and antitumor activity of phenanthroimidazole derivatives as promising c-myc G-quadruplex DNA stabilizers

2020 ◽  
Vol 102 ◽  
pp. 104074
Author(s):  
Qiong Wu ◽  
Yue Song ◽  
Ruotong Liu ◽  
Rui Wang ◽  
Wenjie Mei ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Docking Studies ◽  
Quadruplex Dna ◽  
G Quadruplex

Aggregation and G-quadruplex DNA-binding study of 6a,12a-diazadibenzo-[ a , g ]fluorenylium derivative

2004 ◽  
Vol 14 (14) ◽  
pp. 3627-3630 ◽  
Author(s):  
Bernard Juskowiak ◽  
Elzbieta Galezowska ◽  
Natalia Koczorowska ◽  
Tadeusz W Hermann
Keyword(s):  
Dna Binding ◽  
Binding Study ◽  
Quadruplex Dna ◽  
G Quadruplex

Anticancer activity and DNA binding property of the dimers of triphenylethylene–coumarin hybrid with two amino side chains

2014 ◽  
Vol 24 (6) ◽  
pp. 2314-2324 ◽  
Author(s):  
Mo Zhu ◽  
Likai Zhou ◽  
Yuchao Yao ◽  
Shuai Li ◽  
Mengjiao Lv ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Binding Property ◽  
Side Chains ◽  
Dna Binding Property
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