In vivo efficacy studies of novel quinazoline derivatives as irreversible dual EGFR/HER2 inhibitors, in lung cancer xenografts (NCI-H1975) mice models

2020 ◽  
Vol 99 ◽  
pp. 103790
Author(s):  
Debasis Das ◽  
Lingzhi Xie ◽  
Jingbing Wang ◽  
Jingli Shi ◽  
Jian Hong
Keyword(s):  
Lung Cancer ◽  
In Vivo Efficacy ◽  
Quinazoline Derivatives ◽  
Efficacy Studies

scholarly journals In vivo efficacy of STI571 in xenografted human small cell lung cancer alone or combined with chemotherapy

2004 ◽  
Vol 113 (5) ◽  
pp. 849-856 ◽  
Author(s):  
Didier Decaudin ◽  
Patricia de Cremoux ◽  
Xavier Sastre ◽  
Jean-Gabriel Judde ◽  
Fariba Nemati ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
In Vivo Efficacy

Abstract 4818: In vivo efficacy of triplet therapy with osimertinib, cetuximab and bevacizumab for lung cancer cells harboring EGFR T790M

2018 ◽  
Author(s):  
Kazuya Nishii ◽  
Kadoaki Ohashi ◽  
Go Makimoto ◽  
Hisao Higo ◽  
Kiichiro Ninomiya ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Cells ◽  
Lung Cancer Cells ◽  
In Vivo Efficacy ◽  
Egfr T790m

scholarly journals In Vitro and in Vivo Efficacy of NBDHEX on Gefitinib-resistant Human Non-small Cell Lung Cancer

2020 ◽  
Vol 11 (24) ◽  
pp. 7216-7223
Author(s):  
Huanhuan Sha ◽  
Shuchen Dong ◽  
Chen Yu ◽  
Renrui Zou ◽  
Yue Zhu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
In Vivo Efficacy

In vivo efficacy studies of layer-by-layer nano-matrix bearing kaempferol for the conditions of osteoporosis: A study in ovariectomized rat model

2012 ◽  
Vol 82 (3) ◽  
pp. 508-517 ◽  
Author(s):  
Avinash Kumar ◽  
Girish K. Gupta ◽  
Vikram Khedgikar ◽  
Jyoti Gautam ◽  
Priyanka Kushwaha ◽  
...  
Keyword(s):  
Rat Model ◽  
Ovariectomized Rat ◽  
Layer By Layer ◽  
In Vivo Efficacy ◽  
Efficacy Studies

scholarly journals Multigram Synthesis and in Vivo Efficacy Studies of a Novel Multitarget Anti-Alzheimer’s Compound

Molecules ◽  
2015 ◽  
Vol 20 (3) ◽  
pp. 4492-4515 ◽  
Author(s):  
Irene Sola ◽  
Elisabet Viayna ◽  
Tània Gómez ◽  
Carles Galdeano ◽  
Matteo Cassina ◽  
...  
Keyword(s):  
In Vivo Efficacy ◽  
Efficacy Studies

In Vitro and In Vivo Sequestration of Phencyclidine by Me4Cucurbit[8]uril

2020 ◽  
Author(s):  
Steven Murkli ◽  
Jared Klemm ◽  
Adam T. Brockett ◽  
Michael Shuster ◽  
Volker Briken ◽  
...  
Keyword(s):  
Drugs Of Abuse ◽  
In Vivo Efficacy ◽  
In Vitro Binding ◽  
In Vivo Assays ◽  
Vitro Binding ◽  
Efficacy Studies

This work describes the in vitro binding of CB[8] and Me4CB[8] toward a panel of 10 drugs of abuse, and in vitro and in vivo assays to demonstrate the biocompatibility of Me4CB[8]. In vivo efficacy studies show that Me4CB[8] can control the hyper locomotion of animals treated with PCP.

Development of stabilized Paclitaxel nanocrystals: In-vitro and in-vivo efficacy studies

2015 ◽  
Vol 69 ◽  
pp. 51-60 ◽  
Author(s):  
Shweta Sharma ◽  
Ashwni Verma ◽  
B. Venkatesh Teja ◽  
Prashant Shukla ◽  
Prabhat Ranjan Mishra
Keyword(s):  
In Vivo Efficacy ◽  
Efficacy Studies

scholarly journals In vivo Efficacy Studies in Cell Line and Patient-derived Xenograft Mouse Models

BIO-PROTOCOL ◽  
2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Elizabeth Tovar ◽  
Curt Essenburg ◽  
Carrie Graveel
Keyword(s):  
Cell Line ◽  
Mouse Models ◽  
In Vivo Efficacy ◽  
Patient Derived Xenograft ◽  
Efficacy Studies
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