MiR-661 contributed to cell proliferation of human ovarian cancer cells by repressing INPP5J expression

2015 ◽  
Vol 75 ◽  
pp. 123-128 ◽  
Author(s):  
Tongyu Zhu ◽  
Jing Yuan ◽  
Yuzhi Wang ◽  
Cuiping Gong ◽  
Yudou Xie ◽  
...  
Author(s):  
Mahsa Sabet ◽  
Mohammadreza Sharifi ◽  
Mansour Heidari ◽  
Mohammad Kazemi ◽  
Nahid Babaei

2020 ◽  
Vol 10 (10) ◽  
pp. 1615-1619
Author(s):  
Shuai Zhang ◽  
Junhui Liang ◽  
Changzhong Li ◽  
Fei Wang

To investigate the pharmacodynamic effect of urushin nanoparticles upon the proliferation inhibition in human ovarian cancer SKOV3 cells, and in order to explore their biomechanism, the cell cycle and the percentage of apoptotic cells in human ovarian cancer SKOV3 cells were analyzed utilizing flow cytometry. The concentration of astragalin nanoparticles in SKOV3 cells was identified utilizing HPIC. Consequently, the morphological characteristics of SKOV3 cells in a culture medium of 5 mg/L were investigated and measured. In our findings, the 50 mg cancer cells containing 50 mg IC did not display this noted effect. The results exhibit the discovery that urushin nanoparticles inhibit cell proliferation, which is related to the inhibition of DNA replication and the regulation of the cell proliferation cycle. HPLC results demonstrated that the pharmacological effect of urushin nanoparticles was directly related to the drug concentration present within the studied cells. Hence, urushin nanoparticles can effectively enter cells and then effectively inhibit cell proliferation.


2016 ◽  
Vol 77 ◽  
pp. 92-97 ◽  
Author(s):  
Ai-Hua Wu ◽  
Yu-ling Huang ◽  
Lan-Zhen Zhang ◽  
Geng Tian ◽  
Qiong-Zhi Liao ◽  
...  

2016 ◽  
Vol 5 (1) ◽  
pp. 331-339
Author(s):  
Lea-Yea Chuang ◽  
Jinn-Yuh Guh ◽  
Yi-Ling Ye ◽  
Ying-Ho Lee ◽  
Jau-Shyang Huang

Probucol is considered to be an important agent in promoting anti-oxidative action and protecting against tissue injury.


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