A universal platform for sensitive and selective colorimetric DNA detection based on Exo III assisted signal amplification

2011 ◽  
Vol 26 (5) ◽  
pp. 2796-2800 ◽  
Author(s):  
Liang Cui ◽  
Guoliang Ke ◽  
Wei Yun Zhang ◽  
Chaoyong James Yang
Keyword(s):  
Signal Amplification ◽  
Dna Detection ◽  
Exo Iii

Nanosurface energy transfer indicating Exo III-propelled stochastic 3D DNA walkers for HIV DNA detection

The Analyst ◽  
2021 ◽  
Author(s):  
Na Wang ◽  
Yong Jian Jiang ◽  
Xu Zhang ◽  
Hua Rong Lin ◽  
Feng Cheng ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Signal Amplification ◽  
Dna Detection ◽  
Hiv Dna ◽  
Dna Walker ◽  
Exo Iii ◽  
Dna Walkers

An Exo III-propelled stochastic 3D DNA walker based on nanosurface energy transfer was developed for enzyme-assisted DNA detection with signal amplification.

Highly sensitive lung cancer DNA detection via GO enhancing eATRP signal amplification

2021 ◽  
Vol 160 ◽  
pp. 105766
Author(s):  
Qianrui Liu ◽  
Jingliang Liu ◽  
Huaixia Yang ◽  
Xuchun Wang ◽  
Jinming Kong ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Signal Amplification ◽  
Dna Detection ◽  
Highly Sensitive

Signal amplification for DNA detection based on the HRP-functionalized Fe3O4 nanoparticles

Talanta ◽  
2011 ◽  
Vol 84 (2) ◽  
pp. 531-537 ◽  
Author(s):  
Xiao-Ya Dong ◽  
Xiao-Na Mi ◽  
Bo Wang ◽  
Jing-Juan Xu ◽  
Hong-Yuan Chen
Keyword(s):  
Fe3o4 Nanoparticles ◽  
Signal Amplification ◽  
Dna Detection

scholarly journals Turn-On Fluorescence Aptasensor on Magnetic Nanobeads for Aflatoxin M1 Detection Based on an Exonuclease III-Assisted Signal Amplification Strategy

Nanomaterials ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 104
Author(s):  
Fuyuan Zhang ◽  
Linyang Liu ◽  
Shengnan Ni ◽  
Jiankang Deng ◽  
Guo-Jun Liu ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Aflatoxin M1 ◽  
Exonuclease Iii ◽  
Sensor Performance ◽  
Milk Samples ◽  
Increased Sensitivity ◽  
Exo Iii ◽  
Amplification Strategy ◽  
Optimized Conditions ◽  
Magnetic Nanobeads

In order to satisfy the need for sensitive detection of Aflatoxin M1 (AFM1), we constructed a simple and signal-on fluorescence aptasensor based on an autocatalytic Exonuclease III (Exo III)-assisted signal amplification strategy. In this sensor, the DNA hybridization on magnetic nanobeads could be triggered by the target AFM1, resulting in the release of a single-stranded DNA to induce an Exo III-assisted signal amplification, in which numerous G-quadruplex structures would be produced and then associated with the fluorescent dye to generate significantly amplified fluorescence signals resulting in the increased sensitivity. Under the optimized conditions, this aptasensor was able to detect AFM1 with a practical detection limit of 9.73 ng kg−1 in milk samples. Furthermore, the prepared sensor was successfully used for detection of AFM1 in the commercially available milk samples with the recovery percentages ranging from 80.13% to 108.67%. Also, the sensor performance was evaluated by the commercial immunoassay kit with satisfactory results.

Ultrasensitive DNA Detection Based on Inorganic–Organic Nanocomposite Cosensitization and G-Quadruplex/Hemin Catalysis for Signal Amplification

2020 ◽  
Vol 12 (38) ◽  
pp. 42604-42611
Author(s):  
Pei Miao ◽  
Chaomin Gao ◽  
Mengjiao Hao ◽  
Congcong Zhang ◽  
Zengjun Li ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Dna Detection ◽  
G Quadruplex

Multi-signal amplification electrochemical DNA biosensor based on exonuclease III and tetraferrocene

2020 ◽  
Vol 8 (18) ◽  
pp. 4143-4150
Author(s):  
Zhaojiang Yin ◽  
Hanfeng Cui ◽  
Qingxia Shu ◽  
Chen Jin ◽  
Yan Lin ◽  
...  
Keyword(s):  
Benzoic Acid ◽  
Electrochemical Sensor ◽  
Signal Amplification ◽  
Dna Biosensor ◽  
Exonuclease Iii ◽  
Electrochemical Dna Biosensor ◽  
Exo Iii

A new and efficient signal marker, 3,5-bis(3,5-bisferrocenethoxybenzyloxy)benzoic acid, was firstly synthesized and used for labeling. Construct a homogeneous electrochemical sensor with Exo III assisting the target cycle.

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