Ultrasensitive electrochemical detection of microRNA-21 with wide linear dynamic range based on dual signal amplification

2019 ◽  
Vol 131 ◽  
pp. 267-273 ◽  
Author(s):  
Wen-Jing Guo ◽  
Zhen Wu ◽  
Xiao-Yan Yang ◽  
Dai-Wen Pang ◽  
Zhi-Ling Zhang
2017 ◽  
Vol 52 (6) ◽  
pp. 1605-1617 ◽  
Author(s):  
Juan Antonio Lenero-Bardallo ◽  
Ricardo Carmona-Galan ◽  
Angel Rodriguez-Vazquez

2018 ◽  
Vol 101 (1) ◽  
pp. 208-215 ◽  
Author(s):  
Hadi Beitollahi ◽  
Abbas Gholami ◽  
Mohammad Reza Ganjali

Abstract In this work, a carbon paste electrode modified with Ag-ZnO nanoplates and 2-chlorobenzoyl ferrocene was prepared and applied for the determination of d-penicillamine in the presence of tryptophan. The morphologies of Ag-ZnO nanoplates were examined by scanning electron microscopy. It was found that under an optimum condition (pH 7.0), the oxidation of d-penicillamine at the surface of such an electrode occurs at a potential about 165 mV less positive than that of an unmodified carbon paste electrode. The diffusion coefficient (D = 7.6 × 10−6 cm2/s) and the electron transfer coefficient (α = 0.54) for d-penicillamine oxidation were also determined. The proposed method exhibited a wide linear dynamic range of 0.03–250.0 µM, with an LOD (S/N = 3) of 0.015 µM. Moreover, the modified electrode exhibited good reproducibility and high selectivity, demonstrating its feasibility for the analytical purpose. Lastly, this new sensor was used for the determination of d-penicillamine and tryptophan in real samples.


Small ◽  
2020 ◽  
Vol 16 (52) ◽  
pp. 2005626
Author(s):  
Yudi Tu ◽  
Yan Xu ◽  
Junzi Li ◽  
Qiaoyan Hao ◽  
Xiaosong Liu ◽  
...  

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3208
Author(s):  
Somayeh Tajik ◽  
Hadi Beitollahi ◽  
Sayed ali Ahmadi ◽  
Mohammad Bagher Askari ◽  
Antonio Di Bartolomeo

We developed a novel hydroxylamine sensor through the surface modification of screen-printed electrode (SPE) with NiCo2O4 nanoparticles/reduced graphene oxide (RGO) nanocomposite (NiCo2O4/RGO/SPE). We assessed the electrochemical response of hydroxylamine on the as-fabricated sensor, confirming the high electrocatalytic impact of hydroxylamine oxidation. The electrode produced sensitively responded to hydroxylamine under optimized conditions, with a low limit of detection (2.0 nM) and broad linear dynamic range (0.007–385.0 µM). The presence of NiCo2O4 combined with the modification of RGO resulted in sensitive detection and signal amplification of hydroxylamine oxidation. The proposed sensor was used to determine the existence of hydroxylamine in water samples.


1989 ◽  
Vol 43 (3) ◽  
pp. 422-425 ◽  
Author(s):  
Richard T. Madison ◽  
Mary K. Carroll ◽  
Gary M. Hieftje

A sample cell for observing the Shpol'skii effect at 77 K is described and analytically assessed. The cell employs fiber-optic light guides to transport excitation and emission radiation. The system is compact, inexpensive, and simple to construct from commercially available laboratory components, and it alleviates several problems inherent in conventional refrigerated-cell designs. Detection limits for anthracene, coronene, and pyrene obtained with the sample cell are 8.8 × 10−8 M, 8.4 × 10−7 M, and 3.5 × 10−7 M, respectively. The linear dynamic range for each compound is 2 to 3 orders of magnitude.


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