Primary apocrine carcinoma of scalp: Report of primary scalp cutaneous apocrine carcinoma indistinguishable from cutaneous metastasis of breast carcinoma

2012 ◽  
Vol 65 (3) ◽  
pp. e67-e70 ◽  
Author(s):  
Han Koo Kim ◽  
Kun Il Chung ◽  
Bo Young Park ◽  
Tae Hui Bae ◽  
Woo Seob Kim ◽  
...  
2011 ◽  
Vol 61 (4) ◽  
pp. 531-535
Author(s):  
Michio Maemura ◽  
Takashi Roppongi ◽  
Kotaro Iwanami ◽  
Yuki Numaga ◽  
Miki Tsuboi ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Jyotsna V. Wader ◽  
Akash Jain ◽  
Suresh J. Bhosale ◽  
Pandurang G. Chougale ◽  
Sujata S. Kumbhar

Apocrine carcinoma is a very rare form of breast malignancy with an incidence of <1% of female invasive breast carcinoma. We report a case of apocrine carcinoma in a 42-year female with marked adenosis showing apocrine metaplasia and discuss the criteria to diagnose apocrine carcinoma with the emerging concept of androgen receptor positivity with its implication on treatment and management of the patient.


Author(s):  
Maria Croce ◽  
Amalia Luna ◽  
Maria Emilia Merino ◽  
Cecilio G. Alberdi ◽  
Martin Abba ◽  
...  

2009 ◽  
Vol 102 (4) ◽  
pp. 385-389 ◽  
Author(s):  
Kelly B. Conner ◽  
Philip R. Cohen

2008 ◽  
Vol 35 (3) ◽  
pp. 332-336 ◽  
Author(s):  
Bettina G. Zelger ◽  
Ingrid Stelzmueller ◽  
Karin M. Dunst ◽  
Bernhard Zelger

2013 ◽  
Vol 88 (4) ◽  
pp. 608-610 ◽  
Author(s):  
Gabriela Mantovanelli de Oliveira ◽  
Daniele Bueno Carvalho Zachetti ◽  
Hugo Rocha Barros ◽  
Adriana Tiengo ◽  
Ney Romiti

Cutaneous metastasis is a phenomenon that results from a tumor spreading via lymphatic or vascular embolization, direct implant during surgery or skin involvement by contiguity. The primary malignant tumor that most commonly metastasizes to the skin in women is breast cancer, which can be manifested through papulonodular lesions, erysipeloid or sclerodermiform infiltration, en cuirasse. We report the case of a female patient, 78 years old, with papular, scaly and confluent lesions in the right breast for one year, progressing to edema and skin infiltration, reduction of breast volume and plaque en cuirasse, and similar lesions in the contralateral breast and abdomen for four months. The pathological diagnosis was invasive ductal breast carcinoma with Paget-like foci, epidermal skin metastases and lymphatic embolization.


Author(s):  
Sunanda Nayak ◽  
Snigdha Rani Nahak ◽  
Kailash Chandra Agrawal

Introduction: Apocrine Carcinoma (AC) of breast is a rare breast cancer comprising only 0.3-1.0% of all breast cancers. Microscopically, Invasive Duct Carcinoma of No Special Type (IDC-NST) and AC have similar architecture, but they differ in cell morphology. Immunohistochemistry for both the tumour types is also different. Aim: This study was undertaken to know the incidence of AC and analyse them with respect to different clinicopathological features and compare them with that of IDC-NST. Materials and Methods: This was an observational study conducted in Department of Pathology, Veer Surendra Sai Institute of Medical Science and Research, Burla from March 2010 to February 2019. Patients diagnosed as invasive breast carcinoma were taken as study group. Breast cancer in male patients and female patients taking neoadjuvant chemotherapy were excluded from study group. Clinical features, pathological features and immunohistochemical findings of IDC-NST and AC were studied and statistical data were analysed by SPSS version 23.0 for windows. Comparison of data was done by using Pearson’s Chi-square test. Results having p-value <0.05 were accepted as significant. Results: During the 10 years, 05 cases of AC and 560 cases of IDC-NST were found. Mean age of presentation of AC was 59.5 years and that of IDC-NST was 50.4 years. Most cases of AC and IDC-NST presented with breast lump of size >5 cm. Low grade (grade 1) carcinoma was seen in 20% of AC. Immunohistochemistry showed 3 (60%) cases of AC as triple negative, whereas 213 (38.2%) of IDC-NST were triple negative. All the cases of AC were Gross Cystic Disease Fluid Protein (GCDFP-15) and CK-7 positive. Conclusion: AC is a rare category of breast cancer. Although prognosis of AC and IDC are almost similar, correct diagnosis of AC is important as antiandrogenic therapy can be given to Androgen Receptor (AR) positive AC cases.


2020 ◽  
Vol 11 (5) ◽  
pp. 828
Author(s):  
SatyendraK Singh ◽  
Radhika Raheja ◽  
Vijay Kumar ◽  
PrasannaK Jha

1998 ◽  
Vol 20 (6) ◽  
pp. 609
Author(s):  
E. MUÑOZ ◽  
M. ELICES ◽  
S. CORDOBA ◽  
J. FRAGA

2018 ◽  
Vol 72 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Clare D'Arcy ◽  
Cecily M Quinn

Pure apocrine carcinoma of the breast is rare and has been defined by using a combination of morphologic (apocrine morphology in >90% of tumour cells) and immunohistochemical criteria (oestrogen receptor (ER) and progesterone receptor (PR) negative and androgen receptor (AR) positive). Recent advances in the molecular classification of breast tumours have uncovered a subset of breast tumours associated with high expression of androgen receptor mRNA including the so-called ‘luminal androgen receptor (LAR) tumours’ and ‘molecular apocrine tumours’ (MATs). Recognition of these tumour subsets has opened potential avenues for therapies exploiting the AR pathway in triple negative breast carcinoma (TNBC). In this second part of our two-part review, we focus on the definition of pure apocrine carcinoma, recent advances in understanding the molecular apocrine signature in breast carcinoma, its relationship to pure apocrine carcinoma defined at the level of light microscopy and immunohistochemistry (IHC) and the therapeutic implications of androgen expression in TNBC. We complete the article with a summary of the utility of IHC in stratifying apocrine lesions of the breast.


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