Synthesis, cytotoxic activities and structure–activity relationships of topoisomerase I inhibitors: Indolizinoquinoline-5,12-dione derivatives

2008 ◽  
Vol 16 (8) ◽  
pp. 4617-4625 ◽  
Author(s):  
Yu Cheng ◽  
Lin-Kun An ◽  
Ning Wu ◽  
Xiao-Dong Wang ◽  
Xian-Zhang Bu ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Cytotoxic Activities ◽  
Structure Activity Relationships ◽  
Topoisomerase I Inhibitors ◽  
Structure Activity

scholarly journals The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode

2010 ◽  
Vol 18 (15) ◽  
pp. 5535-5552 ◽  
Author(s):  
Maris A. Cinelli ◽  
Andrew E. Morrell ◽  
Thomas S. Dexheimer ◽  
Keli Agama ◽  
Surbhi Agrawal ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Binding Mode ◽  
Structure Activity Relationships ◽  
Topoisomerase I Inhibitors ◽  
Structure Activity

ChemInform Abstract: Structure-Activity Relationships for Analogues of the Phenazine-Based Dual Topoisomerase I/II Inhibitor XR11576.

ChemInform ◽  
2010 ◽  
Vol 33 (24) ◽  
pp. no-no
Author(s):  
Shouming Wang ◽  
Warren Miller ◽  
John Milton ◽  
Nigel Vicker ◽  
Alistair Stewart ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Abstract Structure

Bis(phenazine-1-carboxamides):  Structure−Activity Relationships for a New Class of Dual Topoisomerase I/II-Directed Anticancer Drugs

2000 ◽  
Vol 43 (7) ◽  
pp. 1350-1358 ◽  
Author(s):  
Julie A. Spicer ◽  
Swarna A. Gamage ◽  
Gordon W. Rewcastle ◽  
Graeme J. Finlay ◽  
David J. A. Bridewell ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Topoisomerase I ◽  
Structure Activity Relationships ◽  
New Class ◽  
Structure Activity

Novel glitazones: glucose uptake and cytotoxic activities, and structure–activity relationships

2011 ◽  
Vol 21 (9) ◽  
pp. 2689-2701 ◽  
Author(s):  
B. R. Prashantha Kumar ◽  
S. Santhosh Kumar ◽  
Patel Viral ◽  
Ashish Wadhwani ◽  
R. Vadivelan ◽  
...  
Keyword(s):  
Glucose Uptake ◽  
Cytotoxic Activities ◽  
Structure Activity Relationships ◽  
Structure Activity

Inhibitory activities against topoisomerase I and II by isoaurostatin derivatives and their structure–activity relationships

2005 ◽  
Vol 15 (8) ◽  
pp. 2065-2068 ◽  
Author(s):  
Keitarou Suzuki ◽  
Tadashi Okawara ◽  
Tatuya Higashijima ◽  
Kazumi Yokomizo ◽  
Tohru Mizushima ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Inhibitory Activities
Sign in / Sign up

Export Citation Format

Share Document