Bis(phenazine-1-carboxamides):  Structure−Activity Relationships for a New Class of Dual Topoisomerase I/II-Directed Anticancer Drugs

2000 ◽  
Vol 43 (7) ◽  
pp. 1350-1358 ◽  
Author(s):  
Julie A. Spicer ◽  
Swarna A. Gamage ◽  
Gordon W. Rewcastle ◽  
Graeme J. Finlay ◽  
David J. A. Bridewell ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Topoisomerase I ◽  
Structure Activity Relationships ◽  
New Class ◽  
Structure Activity

ChemInform Abstract: Structure-Activity Relationships for Analogues of the Phenazine-Based Dual Topoisomerase I/II Inhibitor XR11576.

ChemInform ◽  
2010 ◽  
Vol 33 (24) ◽  
pp. no-no
Author(s):  
Shouming Wang ◽  
Warren Miller ◽  
John Milton ◽  
Nigel Vicker ◽  
Alistair Stewart ◽  
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Keyword(s):  
Topoisomerase I ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Abstract Structure

scholarly journals Synthesis and Structure-Activity Relationships of Substituted 2-((2-Imidazolylsulfinyl)methyl)anilines as a New Class of Gastric H+/K+ -ATPase Inhibitors. II.

1992 ◽  
Vol 40 (3) ◽  
pp. 675-682
Author(s):  
Tomio YAMAKAWA ◽  
Hitoshi MATSUKURA ◽  
Yutaka NOMURA ◽  
Mitsuko YOSHIOKA ◽  
Mitsuo MASAKI ◽  
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Keyword(s):  
Structure Activity Relationships ◽  
New Class ◽  
Structure Activity ◽  
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Design, synthesis & structure–activity relationships of a new class of antihuman enterovirus D68 & A71 agents

2018 ◽  
Vol 10 (11) ◽  
pp. 1333-1347
Author(s):  
Bidyadhar Sethy ◽  
Chung-Fan Hsieh ◽  
Chieh Yeh ◽  
Jim-Tong Horng ◽  
Pei-Wen Hsieh
Keyword(s):  
Design Synthesis ◽  
Structure Activity Relationships ◽  
New Class ◽  
Structure Activity ◽  
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scholarly journals The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode

2010 ◽  
Vol 18 (15) ◽  
pp. 5535-5552 ◽  
Author(s):  
Maris A. Cinelli ◽  
Andrew E. Morrell ◽  
Thomas S. Dexheimer ◽  
Keli Agama ◽  
Surbhi Agrawal ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Binding Mode ◽  
Structure Activity Relationships ◽  
Topoisomerase I Inhibitors ◽  
Structure Activity
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