Synthesis and disulfide bond connectivity–activity studies of a kalata B1-inspired cyclopeptide against dengue NS2B–NS3 protease

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.12.026 ◽

2010 ◽

Vol 18 (3) ◽

pp. 1331-1336 ◽

Author(s):

Yaojun Gao ◽

Taian Cui ◽

Yulin Lam

Keyword(s):

Disulfide Bond ◽

Kalata B1 ◽

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Klonale Analyse von Mutationen der HCV NS3 Protease bei Genotyp 1 Non-Respondern, die mit Boceprevir (SCH503034) behandelt wurden

Zeitschrift für Gastroenterologie ◽

10.1055/s-0028-1089356 ◽

2008 ◽

Vol 46 (09) ◽

Author(s):

S Susser ◽

MW Welker ◽

M Zettler ◽

A Dragan ◽

E Hughes ◽

...

Keyword(s):

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Disulfide Bond Structure and Accessibility of Cysteines in the Ectodomain of the Cholecystokinin Receptor: Specific Mono-Reactive Receptor Constructs Examine Charge-Sensitivity of Loop Regions

Receptors and Channels ◽

10.3109/10606820308249 ◽

2003 ◽

Vol 9 (2) ◽

pp. 83-91

Author(s):

Xi-Qin Ding ◽

Vesile Dolu ◽

Elizabeth M. Hadac ◽

Michael Schuetz ◽

Laurence J. Miller

Keyword(s):

Disulfide Bond ◽

Cholecystokinin Receptor ◽

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Faculty Opinions recommendation of Shedding light on disulfide bond formation: engineering a redox switch in green fluorescent protein.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002310.28155 ◽

2001 ◽

Author(s):

Thomas Nystrom

Keyword(s):

Green Fluorescent Protein ◽

Disulfide Bond ◽

Fluorescent Protein ◽

Bond Formation ◽

Disulfide Bond Formation ◽

Redox Switch ◽

Green Fluorescent

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Faculty Opinions recommendation of Macrocyclic inhibitors of the NS3 protease as potential therapeutic agents of hepatitis C virus infection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1013785.191905 ◽

2003 ◽

Author(s):

Dennis Hall

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Virus Infection ◽

Therapeutic Agents ◽

Hepatitis C Virus Infection ◽

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Faculty Opinions recommendation of Protein disulfide bond formation in the cytoplasm during oxidative stress.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1018579.218434 ◽

2004 ◽

Author(s):

Ruma Banerjee

Keyword(s):

Oxidative Stress ◽

Disulfide Bond ◽

Bond Formation ◽

Disulfide Bond Formation ◽

Protein Disulfide

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Faculty Opinions recommendation of Development of a GB virus B marmoset model and its validation with a novel series of hepatitis C virus NS3 protease inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017920.207523 ◽

2004 ◽

Author(s):

Jeffrey Cohen

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Protease Inhibitors ◽

Ns3 Protease Inhibitors ◽

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Faculty Opinions recommendation of Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1046522.496495 ◽

2006 ◽

Author(s):

Andrew Combs

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Protease Inhibitor ◽

Therapeutic Agent ◽

Hepatitis C Infection ◽

Potential Therapeutic Agent ◽

Orally Bioavailable ◽

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Faculty Opinions recommendation of Modulation of cellular disulfide-bond formation and the ER redox environment by feedback regulation of Ero1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1082833.535764 ◽

2007 ◽

Author(s):

Davis Ng

Keyword(s):

Disulfide Bond ◽

Bond Formation ◽

Feedback Regulation ◽

Disulfide Bond Formation ◽

Redox Environment

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Faculty Opinions recommendation of Crystal structure of the NS3 protease-helicase from dengue virus.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1098445.564009 ◽

2008 ◽

Author(s):

Patricia C Weber

Keyword(s):

Crystal Structure ◽

Dengue Virus ◽

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Faculty Opinions recommendation of Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718020296.793478787 ◽

2013 ◽

Author(s):

Arthur Kim

Keyword(s):

Hepatitis C ◽

Phase 2 ◽

Hepatitis C Infection ◽

Multicentre Phase ◽

Phase 2 Trial ◽

Treatment Naïve ◽

Peginterferon Alfa ◽

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