Peptidic HIV integrase inhibitors derived from HIV gene products: Structure–activity relationship studies

Activity Relationship ◽

Gene Products ◽

Hiv Integrase ◽

Integrase Inhibitors ◽

Structure Activity ◽

Hiv Integrase Inhibitors

Chemistry and Structure-Activity Relationship of the Styrylquinoline-Type HIV Integrase Inhibitors

Molecules ◽

10.3390/molecules15053048 ◽

2010 ◽

Vol 15 (5) ◽

pp. 3048-3078 ◽

Cited By ~ 36

Author(s):

Jean-François Mouscadet ◽

Didier Desmaële

Keyword(s):

Activity Relationship ◽

Hiv Integrase ◽

Integrase Inhibitors ◽

Structure Activity ◽

Hiv Integrase Inhibitors ◽

Relationship Of

Three-Dimensional Quantitative Structure-Activity Relationship (QSAR) of HIV Integrase Inhibitors: A Comparative Molecular Field Analysis (CoMFA) Study

Journal of Medicinal Chemistry ◽

10.1021/jm00006a006 ◽

1995 ◽

Vol 38 (6) ◽

pp. 890-897 ◽

Cited By ~ 60

Author(s):

K. Raghavan ◽

John K. Buolamwini ◽

Mark R. Fesen ◽

Yves Pommier ◽

Kurt W. Kohn ◽

...

Keyword(s):

Three Dimensional ◽

Field Analysis ◽

Comparative Molecular Field Analysis ◽

Hiv Integrase ◽

Quantitative Structure ◽

Integrase Inhibitors ◽

Structure Activity ◽

Hiv Integrase Inhibitors ◽

Comfa Study

The use of ladder particle swarm optimisation for quantitative structure–activity relationship analysis of human immunodeficiency virus-1 integrase inhibitors

Molecular Simulation ◽

10.1080/08927022.2011.586347 ◽

2011 ◽

Vol 37 (15) ◽

pp. 1221-1233 ◽

Cited By ~ 3

Author(s):

Mehdi Jalali-Heravi ◽

Heshmatollah Ebrahimi-Najafabadi

Keyword(s):

Human Immunodeficiency Virus ◽

Activity Relationship ◽

Quantitative Structure ◽

Integrase Inhibitors ◽

Relationship Analysis ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Human Immunodeficiency Virus 1

Discovery and Structure–Activity Relationship Studies of a Unique Class of HIV-1 Integrase Inhibitors

ChemMedChem ◽

10.1002/cmdc.200500018 ◽

2006 ◽

Vol 1 (2) ◽

pp. 238-244 ◽

Cited By ~ 11

Author(s):

Raveendra Dayam ◽

Tino Sanchez ◽

Nouri Neamati

Keyword(s):

Activity Relationship ◽

Integrase Inhibitors ◽

Structure Activity ◽

Hiv 1

Quantitative Structure-Activity Relationship and Docking Studies on a Series of Oxadiazole and Triazole Substituted Naphthyridines as HIV-1 Integrase Inhibitors

Letters in Drug Design & Discovery ◽

10.2174/1570180813666160610090525 ◽

2016 ◽

Vol 14 (1) ◽

pp. 10-27 ◽

Cited By ~ 1

Author(s):

Basheerulla Shaik ◽

Vijay Agrawal ◽

Satya Gupta ◽

Urvana Menon

Keyword(s):

Docking Studies ◽

Activity Relationship ◽

Quantitative Structure ◽

Integrase Inhibitors ◽

Structure Activity ◽

Hiv 1

Structure–activity relationship and binding mode studies for a series of diketo-acids as HIV integrase inhibitors by 3D-QSAR, molecular docking and molecular dynamics simulations

RSC Advances ◽

10.1039/c6ra00713a ◽

2016 ◽

Vol 6 (33) ◽

pp. 27594-27606 ◽

Cited By ~ 3

Author(s):

Dan Han ◽

Min Su ◽

Jianjun Tan ◽

Chunhua Li ◽

Xiaoyi Zhang ◽

...

Keyword(s):

3D Qsar ◽

Binding Mode ◽

Hiv Integrase ◽

Integrase Inhibitors ◽

Factors Affecting ◽

Structure Activity ◽

Main Factors ◽

Dynamics Simulations ◽

Diketo Acids ◽

Hiv Integrase Inhibitors

We explored the main factors affecting the activity of compounds by different statistical and computational methods.

Nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.3109/14756366.2011.604851 ◽

2012 ◽

Vol 27 (5) ◽

pp. 628-640 ◽

Cited By ~ 3

Author(s):

Shenghui Yu ◽

Linna Zhang ◽

Shifeng Yan ◽

Peng Wang ◽

Tino Sanchez ◽

...

Keyword(s):

Biological Activity ◽

Activity Relationship ◽

Integrase Inhibitors ◽

Relationship Analysis ◽

Structure Activity ◽

Hiv 1

Three-dimensional quantitative structure–activity relationship studies on diverse structural classes of HIV-1 integrase inhibitors using CoMFA and CoMSIA

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2006.06.014 ◽

2006 ◽

Vol 41 (12) ◽

pp. 1359-1372 ◽

Cited By ~ 10

Author(s):

Nadtanet Nunthaboot ◽

Somsak Tonmunphean ◽

Vudhichai Parasuk ◽

Peter Wolschann ◽

Sirirat Kokpol

Keyword(s):

Three Dimensional ◽

Activity Relationship ◽

Quantitative Structure ◽

Integrase Inhibitors ◽

Structure Activity ◽

Structural Classes ◽

Hiv 1

Amide-containing diketoacids as HIV-1 integrase inhibitors: Synthesis, structure–activity relationship analysis, and biological activity

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.01.077 ◽

2009 ◽

Vol 17 (7) ◽

pp. 2913-2919 ◽

Cited By ~ 8

Author(s):

Hongcai Li ◽

Chao Wang ◽

Tino Sanchez ◽

Yanmei Tan ◽

Chunying Jiang ◽

...

Keyword(s):

Biological Activity ◽

Activity Relationship ◽

Integrase Inhibitors ◽

Relationship Analysis ◽

Structure Activity ◽

Hiv 1

Quantitative structure-activity relationship of anti-HIV integrase and reverse transcriptase inhibitors using norm indexes

SAR and QSAR in Environmental Research ◽

10.1080/1062936x.2017.1397055 ◽

2017 ◽

Vol 28 (12) ◽

pp. 1025-1044 ◽

Cited By ~ 6

Author(s):

Y. Wang ◽

F. Yan ◽

Q. Jia ◽

Y. Dai ◽

Q. Wang

Keyword(s):

Reverse Transcriptase ◽

Activity Relationship ◽

Hiv Integrase ◽

Quantitative Structure ◽

Reverse Transcriptase Inhibitors ◽

Structure Activity ◽

Relationship Of ◽

Anti Hiv