Efficient synthesis and biological evaluation of ω-oxygenated analogues of vitamin K2: Study of modification and structure–activity relationship of vitamin K2 metabolites

2007 ◽  
Vol 17 (6) ◽  
pp. 1622-1625 ◽  
Author(s):  
Yoshitomo Suhara ◽  
Aya Murakami ◽  
Maya Kamao ◽  
Shino Mimatsu ◽  
Kimie Nakagawa ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Biological Evaluation ◽  
Vitamin K2 ◽  
Activity Relationship ◽  
Efficient Synthesis ◽  
Structure Activity ◽  
Relationship Of ◽  
Synthesis And Biological Evaluation

Design, synthesis and biological evaluation of novel peptide MC2 analogues from Momordica charantia as potential anti-diabetic agents

2015 ◽  
Vol 13 (15) ◽  
pp. 4551-4561 ◽  
Author(s):  
Baowei Yang ◽  
Xue Li ◽  
Chenyu Zhang ◽  
Sijia Yan ◽  
Wei Wei ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Biological Evaluation ◽  
Momordica Charantia ◽  
Activity Relationship ◽  
Design Synthesis ◽  
Structure Activity ◽  
Oxidative Effects ◽  
Relationship Of ◽  
Synthesis And Biological Evaluation

The structure–activity relationship of peptide MC2 resulted in the development of compoundIII-3, which exhibited potent anti-hyperglycaemic and anti-oxidative effects.

scholarly journals Synthesis, Biological Evaluation, and Structure-activity Relationship of Clonazepam, Meclonazepam, and 1,4-Benzodiazepine Compounds with Schistosomicidal Activity

2012 ◽  
Vol 79 (6) ◽  
pp. 943-949 ◽  
Author(s):  
Carla M. S. Menezes ◽  
Gildardo Rivera ◽  
Marina A. Alves ◽  
Daniel N. do Amaral ◽  
Jean Pierre B. Thibaut ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Biological Evaluation ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

Synthesis, biological evaluation and structure–activity relationship of 2-styrylquinazolones as anti-tubercular agents

2016 ◽  
Vol 26 (11) ◽  
pp. 2663-2669 ◽  
Author(s):  
Pradeep S. Jadhavar ◽  
Tejas M. Dhameliya ◽  
Maulikkumar D. Vaja ◽  
Dinesh Kumar ◽  
Jonnalagadda Padma Sridevi ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Biological Evaluation ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

In vitro biological evaluation and consideration about structure-activity relationship of silver(I) aminoacidate complexes

2020 ◽  
Vol 210 ◽  
pp. 111170
Author(s):  
Gabriela Kuzderová ◽  
Michaela Rendošová ◽  
Róbert Gyepes ◽  
Miroslav Almáši ◽  
Danica Sabolová ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Biological Evaluation ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

Synthesis and Antineoplastic Activity of Quinoline Derivatives

2008 ◽  
Vol 61 (7) ◽  
pp. 531 ◽  
Author(s):  
Qiang Zhou ◽  
Jing Hou ◽  
Huamin Li ◽  
Li Cui ◽  
Han Jia ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Structure Activity Relationship ◽  
Biological Evaluation ◽  
Antineoplastic Activity ◽  
Activity Relationship ◽  
Quinoline Derivatives ◽  
Structure Activity ◽  
Relationship Of

Designed as a new series of molecules that contain the quinoline substructure, several 11H-indolo[3.2-c]quinoline derivatives were synthesized and subjected to biological evaluation. Several compounds were found to exhibit cytotoxic activity against the growth of colon (HTC-8), liver (BEL-7402), gastric (BCG-823), pulmonary gland (A549), and ovary (A2780) cancer cell lines. The structure–activity relationship of these compounds is discussed.

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