Current trends in Hedgehog signaling pathway inhibition by small molecules

2018 ◽  
Vol 28 (19) ◽  
pp. 3131-3140 ◽  
Author(s):  
Francesca Ghirga ◽  
Mattia Mori ◽  
Paola Infante
Keyword(s):  
Small Molecules ◽  
Signaling Pathway ◽  
Hedgehog Signaling ◽  
Hedgehog Signaling Pathway ◽  
Current Trends ◽  
Pathway Inhibition

scholarly journals The Utility of Hedgehog Signaling Pathway Inhibition for Cancer

2012 ◽  
Vol 17 (8) ◽  
pp. 1090-1099 ◽  
Author(s):  
Solmaz Sahebjam ◽  
Lillian L. Siu ◽  
Albiruni A. Razak
Keyword(s):  
Signaling Pathway ◽  
Hedgehog Signaling ◽  
Hedgehog Signaling Pathway ◽  
Pathway Inhibition

scholarly journals 4-(Pyrimidin-2-ylamino)benzamide Derivatives：Design, Synthesis, and Hedgehog Signaling Pathway Inhibition Study

2014 ◽  
Vol 34 (7) ◽  
pp. 1407 ◽  
Author(s):  
Liandi Zhang ◽  
Minhang Xin ◽  
Jun Wen ◽  
Feng Tang ◽  
Chongxing Tu ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Hedgehog Signaling ◽  
Hedgehog Signaling Pathway ◽  
Inhibition Study ◽  
Pathway Inhibition

scholarly journals Evaluation of canonical Hedgehog signaling pathway inhibition in canine osteosarcoma

PLoS ONE ◽  
2020 ◽  
Vol 15 (4) ◽  
pp. e0231762
Author(s):  
Vincent E. Baldanza ◽  
Anita Rogic ◽  
Weiwei Yan ◽  
Corri B. Levine ◽  
Roy A. Levine ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Hedgehog Signaling ◽  
Hedgehog Signaling Pathway ◽  
Canine Osteosarcoma ◽  
Pathway Inhibition

scholarly journals Paradoxical prosteatotic effect of hedgehog signaling pathway inhibition under conditions of steatosis

Hepatology ◽  
2012 ◽  
Vol 56 (4) ◽  
pp. 1587-1588 ◽  
Author(s):  
Manuele Gori ◽  
Barbara Barbaro ◽  
Mario Arciello ◽  
Clara Balsano
Keyword(s):  
Signaling Pathway ◽  
Hedgehog Signaling ◽  
Hedgehog Signaling Pathway ◽  
Pathway Inhibition

scholarly journals Synthesis of 2-methoxybenzamide derivatives and evaluation of their hedgehog signaling pathway inhibition

RSC Advances ◽  
2021 ◽  
Vol 11 (37) ◽  
pp. 22820-22825
Author(s):  
Chiyu Sun ◽  
Dajun Zhang ◽  
Tian Luan ◽  
Youbing Wang ◽  
Wenhu Zhang ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Signaling Pathway ◽  
Hedgehog Signaling ◽  
Hedgehog Signaling Pathway ◽  
Daoy Cell ◽  
Pathway Inhibition

Benzamide analog (21) was identified as a potent hedgehog signaling pathway inhibitor that targeted the Smo receptor and blocked Daoy cell proliferation.

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