Functional expression of a highly-reducing polyketide synthase of Emericella variecolor IFM42010, an asteltoxin-producing strain, resulted in production of two polyenoic β-ketolactones with opposite stereochemistry

Makoto Hashimoto; Hitomi Ichijo; Kotaro Fujiwara; Hitoshi Sugasawa; Seika Abo; Kimihito Matsudo; Nahoko Uchiyama; Yukihiro Goda; Isao Fujii

doi:10.1016/j.bmcl.2019.126686

Functional expression of a highly-reducing polyketide synthase of Emericella variecolor IFM42010, an asteltoxin-producing strain, resulted in production of two polyenoic β-ketolactones with opposite stereochemistry

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2019.126686 ◽

2019 ◽

Vol 29 (24) ◽

pp. 126686 ◽

Cited By ~ 1

Author(s):

Makoto Hashimoto ◽

Hitomi Ichijo ◽

Kotaro Fujiwara ◽

Hitoshi Sugasawa ◽

Seika Abo ◽

...

Keyword(s):

Polyketide Synthase ◽

Functional Expression ◽

Emericella Variecolor

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Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster

Journal of Industrial Microbiology & Biotechnology ◽

10.1007/s10295-005-0038-3 ◽

2005 ◽

Vol 33 (1) ◽

pp. 22-28 ◽

Cited By ~ 40

Author(s):

Hugo G. Menzella ◽

Sarah J. Reisinger ◽

Mark Welch ◽

James T. Kealey ◽

Jonathan Kennedy ◽

...

Keyword(s):

Gene Cluster ◽

Polyketide Synthase ◽

Functional Expression ◽

Polyketide Synthase Gene

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The Structure and Rearrangements of a Complete Polyketide Synthase Module During its Catalytic Cycle

Planta Medica ◽

10.1055/s-0033-1348499 ◽

2013 ◽

Vol 79 (10) ◽

Author(s):

DH Sherman ◽

G Skiniotis ◽

JL Smith ◽

K Håkansson ◽

S Dutta ◽

...

Keyword(s):

Polyketide Synthase ◽

Catalytic Cycle

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Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

Diabetes ◽

10.2337/diabetes.44.10.1202 ◽

1995 ◽

Vol 44 (10) ◽

pp. 1202-1208 ◽

Cited By ~ 25

Author(s):

S. Gremlich ◽

A. Porret ◽

E. H. Hani ◽

D. Cherif ◽

N. Vionnet ◽

...

Keyword(s):

Pancreatic Islet ◽

Chromosomal Localization ◽

Functional Expression ◽

Human Pancreatic Islet

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Biotechnology. Modified organisms for application in the environment. Guidance for the characterization of the genetically modified organism by analysis of the functional expression of the genomic modification

10.3403/01448874 ◽

1998 ◽

Keyword(s):

Genetically Modified ◽

Functional Expression ◽

Genetically Modified Organism

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Value management. Functional expression of the need and functional performance specification. Requirements for expressing and validating the need to be satisfied within the process of purchasing or obtaining a product

10.3403/30242720 ◽

2013 ◽

Keyword(s):

Functional Performance ◽

Functional Expression ◽

Value Management ◽

Performance Specification

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Faculty Opinions recommendation of A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1000330.9551 ◽

2001 ◽

Author(s):

Ben Shen

Keyword(s):

Amino Acid ◽

Polyketide Synthase ◽

Proteinogenic Amino Acid

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Faculty Opinions recommendation of Iterative chain elongation by a pikromycin monomodular polyketide synthase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004840.191354 ◽

2003 ◽

Author(s):

Ben Shen

Keyword(s):

Polyketide Synthase ◽

Chain Elongation

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Faculty Opinions recommendation of Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1013751.192152 ◽

2003 ◽

Author(s):

Stephen Dalton

Keyword(s):

Stem Cells ◽

Embryonic Stem Cells ◽

Embryonic Stem ◽

Functional Expression ◽

Expression Cloning

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Faculty Opinions recommendation of Co-expression of a mammalian accessory trafficking protein enables functional expression of the rat MCT1 monocarboxylate transporter in Saccharomyces cerevisiae.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021701.246673 ◽

2004 ◽

Author(s):

Christian Velot

Keyword(s):

Saccharomyces Cerevisiae ◽

Functional Expression ◽

Monocarboxylate Transporter

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Faculty Opinions recommendation of Congenital stationary night blindness type 2 mutations S229P, G369D, L1068P, and W1440X alter channel gating or functional expression of Ca(v)1.4 L-type Ca2+ channels.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1024014.285837 ◽

2005 ◽

Author(s):

Gerald Zamponi

Keyword(s):

Night Blindness ◽

Channel Gating ◽

Functional Expression ◽

Congenital Stationary Night Blindness ◽

Ca2 Channels

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