Fracture incidence, quality of life and back pain in women with osteoporosis and concomitant glucocorticoid use treated with teriparatide: 18-month results from the European Forsteo Observational Study

Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S448-S449 ◽  
Author(s):  
W.F. Lems ◽  
D. Karras ◽  
B.L. Langdahl ◽  
Ö. Ljunggren ◽  
J.B. Walsh ◽  
...  
2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
K. Aloumanis ◽  
D. Karras ◽  
V. Drossinos ◽  
E. Korelis ◽  
A. Polydorakis

Objective. To evaluate fracture incidence, effects on health-related quality of life(QoL), back pain (BP) occurrence and treatment compliance in Greek post-menopausal osteoporotic women treated with teriparatide (TPTD) for up to 18 months, in a naturalistic setting.Methods. 301 patients provided baseline information on demographic characteristics, fracture history, osteoporosis-related medication and risk factors. During treatment, QoL and BP severity were evaluated.Results. Mean (SD) age was 69.5 (±8.5) years. Fracture history was reported by 92.5% of patients. Incidence of fractures (per 10,000 patients/years) ranged from 402 during 0–6 months of treatment, to 346 during 12–18 months. All 5 dimensions of QoL showed improvement. At baseline and 18 months, BP was reported by 93.2% and 64.2% of patients, respectively. BP and limitation of activities were quantified as moderate or severe by 89.9% and 62.3% of patients at baseline versus 32.4% and 14.8% at 18 months. Patients on treatment at 6, 12, 17, and 18 months were 92.6%, 88.3%, 79.6%, and 36.5%, respectively.Conclusions. In the Greek EFOS study cohort, patients prescribed TPTD were severely osteoporotic, with considerable health-related problems. Significant improvements in QoL and BP together with low fracture rates and high compliance have been recorded during treatment.


2016 ◽  
Vol 99 (3) ◽  
pp. 259-271 ◽  
Author(s):  
Bente L. Langdahl ◽  
Östen Ljunggren ◽  
Claude-Laurent Benhamou ◽  
Fernando Marin ◽  
George Kapetanos ◽  
...  

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