scholarly journals Equilibrium Sampling between Membrane Interior and the Aqueous SecYEG Channel Departs from the Biological Hydrophobicity Scale

2020 ◽  
Vol 118 (3) ◽  
pp. 367a
Author(s):  
Denis G. Knyazev ◽  
Roland Kuttner ◽  
Mirjam Zimmermann ◽  
Peter Pohl
Keyword(s):  
Hydrophobicity Scale

Do protein–lipid interactions determine the recognition of transmembrane helices at the ER translocon?

2005 ◽  
Vol 33 (5) ◽  
pp. 1012-1015 ◽  
Author(s):  
S.H. White ◽  
G. von Heijne
Keyword(s):  
Quantitative Information ◽  
Membrane Insertion ◽  
Transmembrane Helices ◽  
Transmembrane Segment ◽  
Hydrophobicity Scale ◽  
Model Protein ◽  
Target Membrane ◽  
Correct Target ◽  
Molecular Code

Membrane-protein integration, folding and assembly processes in vivo depend on complex targeting, translocation, chaperoning, and sorting machineries that somehow read the ‘molecular code’ built into the nascent polypeptide, ultimately producing a properly folded protein integrated into the correct target membrane. Although the main molecular constituents and the basic mechanistic principles of many of these machines are known in outline, the codes remain poorly defined and there is little quantitative information on how protein sequence affects the final structure of membrane proteins. By carefully designing model protein constructs, we have derived the first true biological hydrophobicity scale and have been able to get a first impression of how the position of a given type of residue within a transmembrane segment affects its ability to promote membrane insertion.

Hydrophobicity scale for proteins based on inverse temperature transitions

Biopolymers ◽  
1992 ◽  
Vol 32 (9) ◽  
pp. 1243-1250 ◽  
Author(s):  
Dan W. Urry ◽  
D. Channe Gowda ◽  
Timothy M. Parker ◽  
Chi-Hao Luan ◽  
Michael C. Reid ◽  
...  
Keyword(s):  
Inverse Temperature ◽  
Hydrophobicity Scale

A Hydrophobicity Scale of Heteropoly- and Isopolyanions Based on Voltammetric Studies of Their Transfer at the Nitrobenzene/Water Interface

1993 ◽  
Vol 66 (4) ◽  
pp. 1111-1115 ◽  
Author(s):  
Toshiyuki Osakai ◽  
Hajime Katano ◽  
Kohji Maeda ◽  
Sadayuki Himeno ◽  
Atsuyoshi Saito
Keyword(s):  
Water Interface ◽  
Hydrophobicity Scale ◽  
Voltammetric Studies

scholarly journals An Intrinsic Hydrophobicity Scale for Amino Acids and Its Application to Fluorinated Compounds

2019 ◽  
Vol 58 (24) ◽  
pp. 8216-8220 ◽  
Author(s):  
Waldemar Hoffmann ◽  
Jennifer Langenhan ◽  
Susanne Huhmann ◽  
Johann Moschner ◽  
Rayoon Chang ◽  
...  
Keyword(s):  
Amino Acids ◽  
Hydrophobicity Scale
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