Beneficial effects of treadmill training in a cerebral palsy-like rodent model: Walking pattern and soleus quantitative histology

2008 ◽  
Vol 1222 ◽  
pp. 129-140 ◽  
Author(s):  
Simone Marcuzzo ◽  
Márcio Ferreira Dutra ◽  
Felipe Stigger ◽  
Patrícia Severo do Nascimento ◽  
Jocemar Ilha ◽  
...  
2009 ◽  
Vol 33 (4) ◽  
pp. 339-347 ◽  
Author(s):  
Martin John Matthews ◽  
Martin Watson ◽  
Barbara Richardson

This phase 1 exploratory study aimed to establish proof of concept of the effects of dynamic elastomeric fabric orthoses (DEFOs) on the gait of children with spastic diplegic cerebral palsy. Replicated single case experiments employing an ABA methodology were carried out on eight subjects (median age 5.5 years, range 3–13 years; 4 girls/boys) utilizing quantitative/qualitative data collection. Outcome measures were: Ten metre walking test (10MWT); physiological cost index (PCI); visual analogue scale (VAS) scoring of perceived gait changes; functional mobility changes using Patient Specific Functional Scale (PSFS); subject/carer perceptions recorded in daily diaries. Results identified following analysis of quantitative data indicated a treatment effect from the orthoses which could be corroborated by participant subjective impressions and comments. Statistically significant ( p < 0.05) intervention-related improvements in gait velocity and gait consistency were identified respectively in 5/8 and 4/8 subjects. Power calculations support the feasibility of a larger controlled study to further investigate this orthotic intervention. This study indicates that DEFO leggings can confer beneficial effects on the gait of some children with spastic diplegia resulting from CP. These findings have implications for orthotic intervention with this subject group.


Clinics ◽  
2010 ◽  
Vol 65 (12) ◽  
pp. 1329-1337 ◽  
Author(s):  
Tais Malysz ◽  
Jocemar Ilha ◽  
Patrícia Severo do Nascimento ◽  
Katia De Angelis ◽  
Beatriz D'Agord Schaan ◽  
...  

2013 ◽  
Vol 37 (6) ◽  
pp. 445-453 ◽  
Author(s):  
Ivan YW Su ◽  
Kenny KY Chung ◽  
Daniel HK Chow

Background:Partial body weight-supported treadmill training has been shown to be effective in gait training for patients with neurological disorders such as spinal cord injuries and stroke. Recent applications on children with cerebral palsy were reported, mostly on spastic cerebral palsy with single subject design. There is lack of evidence on the effectiveness of such training for nonspastic cerebral palsy, particularly those who are low functioning with limited intellectual capacity.Objectives:This study evaluated the effectiveness of partial body weight-supported treadmill training for improving gross motor skills among these clients.Study design:A two-period randomized crossover design with repeated measures.Methods:A crossover design following an A–B versus a B–A pattern was adopted. The two training periods consisted of 12-week partial body weight-supported treadmill training (Training A) and 12-week conventional gait training (Training B) with a 10-week washout in between. Ten school-age participants with nonspastic cerebral palsy and severe mental retardation were recruited. The Gross Motor Function Measure-66 was administered immediately before and after each training period.Results:Significant improvements in dimensions D and E of the Gross Motor Function Measure-66 and the Gross Motor Ability Estimator were obtained.Conclusions:Our findings revealed that the partial body weight-supported treadmill training was effective in improving gross motor skills for low-functioning children and adolescents with nonspastic cerebral palsy.Clinical relevanceOur preliminary findings demonstrated that partial body weight-supported treadmill training was a treatment of choice for improving gross motor functioning related to standing and ambulation for low-functioning children and adolescents with nonspastic cerebral palsy and limited intellectual capacity.


2021 ◽  
Vol 90 ◽  
pp. 133-134
Author(s):  
R. Kuijpers ◽  
B.E. Groen ◽  
E. Smulders ◽  
M.W.G. Nijhuis-van der Sanden ◽  
V. Weerdesteyn

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