scholarly journals Edaravone, a free radical scavenger, mitigates both gray and white matter damages after global cerebral ischemia in rats

2009 ◽  
Vol 1279 ◽  
pp. 139-146 ◽  
Author(s):  
Kozue Kubo ◽  
Shinichi Nakao ◽  
Sachiko Jomura ◽  
Sachiyo Sakamoto ◽  
Etsuko Miyamoto ◽  
...  
Keyword(s):  
Free Radical ◽  
White Matter ◽  
Cerebral Ischemia ◽  
Free Radical Scavenger ◽  
Global Cerebral Ischemia ◽  
Radical Scavenger

OPTIMASI KONDISI EKSTRAKSI SENYAWA AKTIF ANTIOKSIDAN DARI BIJI ANGGUR

2019 ◽  
Vol 3 (2) ◽  
pp. 35
Author(s):  
Kartini Kartini ◽  
Azminah Azminah
Keyword(s):  
Free Radical ◽  
Optimum Condition ◽  
Active Compound ◽  
Grape Seed ◽  
Free Radical Scavenger ◽  
Water Bath ◽  
Radical Scavenger ◽  
Optimum Conditions ◽  
Ethanolic Solution ◽  
Reduced Pressure

In order to prepare standardized extract, optimization of extraction conditions of grape seed has been done. These conditions are type of menstrum (50, 70 and 96% of ethanolic solution), length of extraction (1, 2 and 4 hours) also method of evaporation (reduced pressure and opened air). Activity on free radical scavenger used as parameters to determine optimum conditions. Based on EC50 (concentration which scavenge 50% amount of free radical) can be concluded that optimum condition for extracting antioxidant active compound from grape seed are 70% ethanolic solution as menstrum, length of extraction 1 hour and evaporation on opened air use water bath.

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