Upregulation of arginine vasopressin synthesis in the rat hypothalamus after kainic acid-induced seizures

2011 ◽  
Vol 1424 ◽  
pp. 1-8 ◽  
Author(s):  
Masaru Iwanaga ◽  
Motoko Ohno ◽  
Akiko Katoh ◽  
Toyoaki Ohbuchi ◽  
Toru Ishikura ◽  
...  
Keyword(s):  
Kainic Acid ◽  
Arginine Vasopressin ◽  
Rat Hypothalamus ◽  
Vasopressin Synthesis

scholarly journals Effects of acute kidney dysfunction on hypothalamic arginine vasopressin synthesis in transgenic rats

2019 ◽  
Vol 69 (3) ◽  
pp. 531-541 ◽  
Author(s):  
Hiromichi Ueno ◽  
Ryota Serino ◽  
Kenya Sanada ◽  
Yasuki Akiyama ◽  
Kentaro Tanaka ◽  
...  
Keyword(s):  
Arginine Vasopressin ◽  
Transgenic Rats ◽  
Kidney Dysfunction ◽  
Vasopressin Synthesis

4-Phenylalanine analogues of vasopressin: Synthesis, pharmacological and chiroptical properties

1986 ◽  
Vol 51 (7) ◽  
pp. 1532-1541 ◽  
Author(s):  
František Brtník ◽  
Tomislav Barth ◽  
Petr Maloň ◽  
Ivo Frič ◽  
Vija E. Kluša ◽  
...  
Keyword(s):  
Arginine Vasopressin ◽  
Pharmacological Properties ◽  
Cd Spectra ◽  
Chiroptical Properties ◽  
Lysine Vasopressin ◽  
Vasopressin Synthesis

Synthesis, some pharmacological properties and CD spectra of [4-phenylalanine, 8-arginine]vasopressin and [4-phenylalanine, 8-lysine]vasopressin are described.

Oxytocin and vasopressin mRNA expression in rat hypothalamus following kainic acid-induced seizures

Neuroscience ◽  
1996 ◽  
Vol 71 (2) ◽  
pp. 543-554 ◽  
Author(s):  
Q. Sun ◽  
S. Pretel ◽  
C.D. Applegate ◽  
D.T. Piekut
Keyword(s):  
Mrna Expression ◽  
Kainic Acid ◽  
Rat Hypothalamus

scholarly journals Transcription factor CREB3L1 mediates cAMP and glucocorticoid regulation of arginine vasopressin gene transcription in the rat hypothalamus

2015 ◽  
Vol 8 (1) ◽  
Author(s):  
Mingkwan Greenwood ◽  
Michael P. Greenwood ◽  
Andre S. Mecawi ◽  
Su Yi Loh ◽  
José Antunes Rodrigues ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Gene Transcription ◽  
Arginine Vasopressin ◽  
Rat Hypothalamus ◽  
Vasopressin Gene

Effect of acetylcholine and 5-hydroxytryptamine on the secretion of corticotrophin-releasing factor-41 and arginine vasopressin from the rat hypothalamus in vitro

1989 ◽  
Vol 122 (3) ◽  
pp. 713-718 ◽  
Author(s):  
E. W. Hillhouse ◽  
N. G. N. Milton
Keyword(s):  
Arginine Vasopressin ◽  
Bioactive Substances ◽  
Rat Hypothalamus ◽  
Corticotrophin Releasing Factor ◽  
Dose Dependent ◽  
Isolated Rat ◽  
Stimulation Of

ABSTRACT Previous studies using the isolated rat hypothalamus in vitro have shown that both acetylcholine and 5-hydroxytryptamine (5-HT) stimulate the secretion of bioactive corticotrophin-releasing factor (CRF). However, the CRF complex consists of a number of bioactive substances, and in this study we examined the effect of acetylcholine and 5-HT on the release of immunoreactive (ir)-CRF-41 and ir-arginine vasopressin (AVP) in vitro. Acetylcholine caused a dose-dependent (10 pmol–10 nmol/l) release of both neuropeptides, and the effect was partially antagonized by both atropine and hexamethonium. Nicotine (0·1–10 μmol/l) also stimulated the release of both peptides, whereas bethanacol had no effect on AVP release, but had a variable action on CRF-41 release. 5-HT caused a dose-dependent (10 pmol–1 nmol/l) stimulation of CRF-41 release without any effect on AVP release, and this effect was antagonized by cyproheptadine, suggesting the participation of specific 5-HT receptors. Journal of Endocrinology (1989) 122, 713–718

Pattern of MHC class I and immune proteasome expression in Walker 256 tumor during growth and regression in Brattleboro rats with the hereditary defect of arginine-vasopressin synthesis

2011 ◽  
Vol 271 (2) ◽  
pp. 385-391 ◽  
Author(s):  
Liudmila A. Zakharova ◽  
Igor I. Khegai ◽  
Natalia P. Sharova ◽  
Victoria I. Melnikova ◽  
Yaroslava D. Karpova ◽  
...  
Keyword(s):  
Mhc Class I ◽  
Arginine Vasopressin ◽  
Class I ◽  
Brattleboro Rats ◽  
Hereditary Defect ◽  
Walker 256 ◽  
Vasopressin Synthesis ◽  
Walker 256 Tumor

scholarly journals Muscarinic M2 receptor promotes vasopressin synthesis in mice supraoptic nuclei

2018 ◽  
Vol 237 (2) ◽  
pp. 207-216
Author(s):  
Hiroshi Nagano ◽  
Yuki Sobue ◽  
Hayato Matsuyama ◽  
Shoichiro Saito ◽  
Hiroki Sakai ◽  
...  
Keyword(s):  
Arginine Vasopressin ◽  
Knockout Mice ◽  
Receptor Expression ◽  
Muscarinic Agonist ◽  
Wild Type ◽  
Vasopressin Release ◽  
Paraventricular Nuclei ◽  
Vasopressin Secretion ◽  
Vasopressin Synthesis ◽  
Supraoptic Nuclei

Muscarinic acetylcholine receptors have been suggested to be implicated in arginine–vasopressin secretion because intracerebroventricular muscarinic agonist administration induces arginine–vasopressin release into the circulation. Although which subtype is involved in the regulation of arginine–vasopressin secretion is unclear, M2 receptors have been reported to be highly expressed in the hypothalamus. In the present study, M2 receptor-knockout mice were used to elucidate whether M2 receptor regulates arginine–vasopressin synthesis in the paraventricular nuclei and supraoptic nuclei of the hypothalamus. The number of arginine–vasopressin-immunoreactive neurons in M2 receptor-knockout mice was significantly decreased in the supraoptic nuclei, but not in the paraventricular nuclei compared with wild-type mice. Plasma arginine–vasopressin level in M2 receptor-knockout mice was also significantly lower than in the wild-type mice. Urinary volume and frequency as well as water intake in M2 receptor-knockout mice were significantly higher than those in wild-type mice. The V2 vasopressin receptor expression in kidneys of M2 receptor-knockout mice was comparable with that of wild-type mice, and increased urination in M2 receptor-knockout mice was significantly decreased by administration of desmopressin, a specific V2 receptor agonist, suggesting that V2 receptors in the kidneys of M2 receptor-knockout mice are intact. These results suggest that M2 receptors promote arginine–vasopressin synthesis in the supraoptic nuclei and play a role in the regulation and maintenance of body fluid.

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