Silibinin suppresses astroglial activation in a mouse model of acute Parkinson׳s disease by modulating the ERK and JNK signaling pathways

Brain Research ◽

10.1016/j.brainres.2015.09.029 ◽

2015 ◽

Vol 1627 ◽

pp. 233-242 ◽

Author(s):

Yujeong Lee ◽

Hye Jeong Chun ◽

Kyung Moon Lee ◽

Young-Suk Jung ◽

Jaewon Lee

Keyword(s):

Mouse Model ◽

Signaling Pathways ◽

Jnk Signaling ◽

Astroglial Activation

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Faculty Opinions recommendation of Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1088082.541064 ◽

2007 ◽

Author(s):

Patrice Morin

Keyword(s):

Mouse Model ◽

Signaling Pathways ◽

Endometrioid Adenocarcinoma ◽

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Soluble epoxide hydrolase inhibitor trifluoromethoxyphenyl‐3‐(1‐propionylpiperidin‐4‐yl)urea prevents hyperalgesia through regulating NLRC4 inflammasome‐related pro‐inflammatory and anti‐inflammatory signaling pathways in the lipopolysaccharide‐induced pain mouse model

Drug Development Research ◽

10.1002/ddr.21786 ◽

2021 ◽

Author(s):

Ali Cagli ◽

Sefika Pinar Senol ◽

Meryem Temiz‐Resitoglu ◽

Demet Sinem Guden ◽

Ayse Nihal Sari ◽

...

Keyword(s):

Mouse Model ◽

Signaling Pathways ◽

Epoxide Hydrolase ◽

Soluble Epoxide Hydrolase ◽

Inflammatory Signaling ◽

Soluble Epoxide Hydrolase Inhibitor ◽

Anti Inflammatory

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Tetrandrine inhibits migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes through down-regulating the expressions of Rac1, Cdc42, and RhoA GTPases and activation of the PI3K/Akt and JNK signaling pathways

Chinese Journal of Natural Medicines ◽

10.1016/s1875-5364(15)30087-x ◽

2015 ◽

Vol 13 (11) ◽

pp. 831-841 ◽

Author(s):

Qi LV ◽

Xian-Yang ZHU ◽

Yu-Feng XIA ◽

Yue DAI ◽

Zhi-Feng WEI

Keyword(s):

Rheumatoid Arthritis ◽

Signaling Pathways ◽

Migration And Invasion ◽

Jnk Signaling ◽

Fibroblast Like Synoviocytes

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Proanthocyanidins inhibit osteoclast formation and function by inhibiting the NF-κB and JNK signaling pathways during osteoporosis treatment

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2018.12.125 ◽

2019 ◽

Vol 509 (1) ◽

pp. 294-300 ◽

Author(s):

Wei Zhu ◽

Ziqing Yin ◽

Qiang Zhang ◽

Shuangfei Guo ◽

Yi Shen ◽

...

Keyword(s):

Signaling Pathways ◽

Osteoporosis Treatment ◽

Osteoclast Formation ◽

Jnk Signaling ◽

And Function ◽

Inhibit Osteoclast Formation

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Inhibition of H1N1 influenza virus by selenium nanoparticles loaded with zanamivir through p38 and JNK signaling pathways

RSC Advances ◽

10.1039/c7ra06477b ◽

2017 ◽

Vol 7 (56) ◽

pp. 35290-35296 ◽

Author(s):

Zhengfang Lin ◽

Yinghua Li ◽

Min Guo ◽

Misi Xiao ◽

Changbing Wang ◽

...

Keyword(s):

Influenza Virus ◽

Virus Infection ◽

Signaling Pathways ◽

Clinical Application ◽

Influenza Virus Infection ◽

Aqueous Solubility ◽

H1n1 Influenza ◽

Solubility Limit ◽

H1n1 Influenza Virus ◽

Zanamivir is an effective drug for influenza virus infection, but strong molecular polarity and aqueous solubility limit its clinical application.

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Syk and JNK signaling pathways are involved in inflammasome activation in macrophages infected with Streptococcus pneumoniae

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2018.11.011 ◽

2018 ◽

Vol 507 (1-4) ◽

pp. 217-222 ◽

Author(s):

Siwei Feng ◽

Qingyuan Huang ◽

Chao Ye ◽

Rui Wu ◽

Guihua Lei ◽

...

Keyword(s):

Streptococcus Pneumoniae ◽

Signaling Pathways ◽

Inflammasome Activation ◽

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Guavinoside B from Psidium guajava alleviates acetaminophen-induced liver injury via regulating the Nrf2 and JNK signaling pathways

Food & Function ◽

10.1039/d0fo01338b ◽

2020 ◽

Vol 11 (9) ◽

pp. 8297-8308

Author(s):

Yuanyuan Li ◽

Jialin Xu ◽

Dongli Li ◽

Hang Ma ◽

Yu Mu ◽

...

Keyword(s):

Liver Injury ◽

Signaling Pathways ◽

Signaling Pathway ◽

Phenolic Compound ◽

Psidium Guajava ◽

Jnk Signaling ◽

Nrf2 Signaling Pathway ◽

Jnk Signaling Pathway

GUB, a main phenolic compound present in guava fruits, could alleviate APAP-induced liver injury in vitro and in vivo by activating the Nrf2 signaling pathway and inhibiting the JNK signaling pathway.

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Tanshinone IIA induces apoptosis of ovarian cancer cells in�vitro and in�vivo through attenuation of PI3K/AKT/JNK signaling pathways

Oncology Letters ◽

10.3892/ol.2018.9744 ◽

2018 ◽

Author(s):

Xian Zhang ◽

Yong Zhou ◽

Ying‑Er Gu

Keyword(s):

Ovarian Cancer ◽

Cancer Cells ◽

Signaling Pathways ◽

Tanshinone Iia ◽

Ovarian Cancer Cells ◽

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Glycyrrhizic acid suppresses osteoclast differentiation and postmenopausal osteoporosis by modulating the NF-κB, ERK, and JNK signaling pathways

European Journal of Pharmacology ◽

10.1016/j.ejphar.2019.172550 ◽

2019 ◽

Vol 859 ◽

pp. 172550 ◽

Author(s):

Ziqing Yin ◽

Wei Zhu ◽

Qi Wu ◽

Qiang Zhang ◽

Shuangfei Guo ◽

...

Keyword(s):

Signaling Pathways ◽

Postmenopausal Osteoporosis ◽

Glycyrrhizic Acid ◽

Osteoclast Differentiation ◽

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Scutellarin suppresses cartilage destruction in osteoarthritis mouse model by inhibiting the NF-κB and PI3K/AKT signaling pathways

International Immunopharmacology ◽

10.1016/j.intimp.2019.105928 ◽

2019 ◽

Vol 77 ◽

pp. 105928 ◽

Author(s):

Wenhan Wang ◽

Jiayi Li ◽

Feng Li ◽

Jiangfan Peng ◽

Mingyang Xu ◽

...

Keyword(s):

Mouse Model ◽

Signaling Pathways ◽

Cartilage Destruction ◽

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