Conscious perception of movement parameters and content of the primary motor cortex – A Transcranial magnetic stimulation study

The study was conducted on 22 healthy men aged 18-23 years. The primary motor cortex innervating the lower limb was stimulated with transcranial magnetic stimulation. Using transcutaneous electrical stimulation of the spinal cord, evoked motor responses of the muscles of the lower extremities were initiated when electrodes were applied cutaneous between the spinous processes in the Th11-Th12 projection. Research protocol: Determination of the thresholds of BMO of the muscles of the lower extremities during TESCS; determination of the BMO threshold of the TA muscle in TMS; determination of the thresholds of the BMO of the muscles of the lower extremities during TESCS against the background of 80% and 90% TMS. It was found that magnetic stimulation of the motor cortex of the brain leads to an increase in the excitability of the neural structures of the lumbar thickening of the spinal cord and an improvement in neuromuscular interactions. Key words: transcranial magnetic stimulation, transcutaneous electrical stimulation of the spinal cord, neural networks, excitability, neuromuscular interactions.

Download Full-text

A novel dual-site transcranial magnetic stimulation paradigm to probe fast facilitatory inputs from ipsilateral dorsal premotor cortex to primary motor cortex

NeuroImage ◽

10.1016/j.neuroimage.2012.05.023 ◽

2012 ◽

Vol 62 (1) ◽

pp. 500-509 ◽

Cited By ~ 40

Author(s):

Sergiu Groppa ◽

Nicole Werner-Petroll ◽

Alexander Münchau ◽

Günther Deuschl ◽

Matthew F.S. Ruschworth ◽

...

Keyword(s):

Transcranial Magnetic Stimulation ◽

Motor Cortex ◽

Magnetic Stimulation ◽

Primary Motor Cortex ◽

Premotor Cortex ◽

Dorsal Premotor Cortex ◽

Stimulation Paradigm ◽

Dual Site

Download Full-text

Effects of visual deprivation on primary motor cortex excitability: a study on healthy subjects based on repetitive transcranial magnetic stimulation

Experimental Brain Research ◽

10.1007/s00221-017-4945-0 ◽

2017 ◽

Vol 235 (7) ◽

pp. 2059-2067 ◽

Cited By ~ 4

Author(s):

Chiara Cambieri ◽

Elisa Iacovelli ◽

Maria Cristina Gori ◽

Emanuela Onesti ◽

Marco Ceccanti ◽

...

Keyword(s):

Transcranial Magnetic Stimulation ◽

Motor Cortex ◽

Healthy Subjects ◽

Magnetic Stimulation ◽

Primary Motor Cortex ◽

Repetitive Transcranial Magnetic Stimulation ◽

Visual Deprivation ◽

Motor Cortex Excitability

Download Full-text

Motor cortex excitability and fatigue in multiple sclerosis: a transcranial magnetic stimulation study

Multiple Sclerosis Journal ◽

10.1191/1352458505ms1163oa ◽

2005 ◽

Vol 11 (3) ◽

pp. 316-321 ◽

Cited By ~ 82

Author(s):

J Liepert ◽

D Mingers ◽

C Heesen ◽

T Bäumer ◽

C Weiller

Keyword(s):

Multiple Sclerosis ◽

Transcranial Magnetic Stimulation ◽

Motor Cortex ◽

Magnetic Stimulation ◽

Primary Motor Cortex ◽

Motor Task ◽

Time Interval ◽

Membrane Excitability ◽

Motor Cortex Excitability ◽

Fatigue Severity

We investigated electrophysiological correlates of fatigue in patients with multiple sclerosis (MS). Transcranial magnetic stimulation (TMS) was used to explore motor excitability in three groups of subjects: MS patients with fatigue (MS-F), MS patients without fatigue (MS-NF) and healthy control subjects. All participants had to perform a fatiguing hand-grip exercise. TMS was performed prior to and after the exercise. Prior to the motor task, MS-F patients had less inhibition in the primary motor cortex compared to both other groups. Postexercise, intracortical inhibition was still reduced in the MS-F patients compared to the MS-NF patients. In MS-F patients the postexercise time interval for normalization of the motor threshold was correlated with the fatigue severity. We conclude that MS patients with fatigue have an impairment of inhibitory circuits in their primary motor cortex. The results also indicate that fatigue severity is associated with an exercise-induced reduction of membrane excitability.

Download Full-text