Assessing multi-layered nonlinear characteristics of ECG/EEG signal via adaptive kernel density estimation-based hierarchical entropies

2021 ◽  
Vol 67 ◽  
pp. 102520
Author(s):  
Tao Zhang ◽  
Zhiwu Han ◽  
Xiaojuan Chen ◽  
Mingyang Li ◽  
Wanzhong Chen ◽  
...  
2021 ◽  
Vol 8 (4) ◽  
pp. 309-332
Author(s):  
Efosa Michael Ogbeide ◽  
Joseph Erunmwosa Osemwenkhae

Density estimation is an important aspect of statistics. Statistical inference often requires the knowledge of observed data density. A common method of density estimation is the kernel density estimation (KDE). It is a nonparametric estimation approach which requires a kernel function and a window size (smoothing parameter H). It aids density estimation and pattern recognition. So, this work focuses on the use of a modified intersection of confidence intervals (MICIH) approach in estimating density. The Nigerian crime rate data reported to the Police as reported by the National Bureau of Statistics was used to demonstrate this new approach. This approach in the multivariate kernel density estimation is based on the data. The main way to improve density estimation is to obtain a reduced mean squared error (MSE), the errors for this approach was evaluated. Some improvements were seen. The aim is to achieve adaptive kernel density estimation. This was achieved under a sufficiently smoothing technique. This adaptive approach was based on the bandwidths selection. The quality of the estimates obtained of the MICIH approach when applied, showed some improvements over the existing methods. The MICIH approach has reduced mean squared error and relative faster rate of convergence compared to some other approaches. The approach of MICIH has reduced points of discontinuities in the graphical densities the datasets. This will help to correct points of discontinuities and display adaptive density. Keywords: approach, bandwidth, estimate, error, kernel density


BMJ Open ◽  
2014 ◽  
Vol 4 (10) ◽  
pp. e005249 ◽  
Author(s):  
Branko Miladinovic ◽  
Ambuj Kumar ◽  
Rahul Mhaskar ◽  
Benjamin Djulbegovic

ObjectiveTo understand how often ‘breakthroughs,’ that is, treatments that significantly improve health outcomes, can be developed.DesignWe applied weighted adaptive kernel density estimation to construct the probability density function for observed treatment effects from five publicly funded cohorts and one privately funded group.Data Sources820 trials involving 1064 comparisons and enrolling 331 004 patients were conducted by five publicly funded cooperative groups. 40 cancer trials involving 50 comparisons and enrolling a total of 19 889 patients were conducted by GlaxoSmithKline.ResultsWe calculated that the probability of detecting treatment with large effects is 10% (5–25%), and that the probability of detecting treatment with very large treatment effects is 2% (0.3–10%). Researchers themselves judged that they discovered a new, breakthrough intervention in 16% of trials.ConclusionsWe propose these figures as the benchmarks against which future development of ‘breakthrough’ treatments should be measured.


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