A novel BRCA1 germline mutation promotes triple-negative breast cancer cells progression and enhances sensitivity to DNA damage agents

2019 ◽  
Vol 239 ◽  
pp. 26-32 ◽  
Author(s):  
Kun Xu ◽  
Yaqin Shi ◽  
Xin Wang ◽  
Yajuan Chen ◽  
Lin Tang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Damage ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Germline Mutation ◽  
Breast Cancer Cells ◽  
Triple Negative

scholarly journals Jadomycins Inhibit Type II Topoisomerases and Promote DNA Damage and Apoptosis in Multidrug-Resistant Triple-Negative Breast Cancer Cells

2017 ◽  
Vol 363 (2) ◽  
pp. 196-210 ◽  
Author(s):  
Steven R. Hall ◽  
Jay Toulany ◽  
Leah G. Bennett ◽  
Camilo F. Martinez-Farina ◽  
Andrew W. Robertson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Damage ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Multidrug Resistant ◽  
Type Ii

scholarly journals HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

Oncotarget ◽  
2016 ◽  
Vol 7 (40) ◽  
pp. 64820-64835 ◽  
Author(s):  
Meghna Mehta ◽  
Kanthesh Basalingappa ◽  
James N. Griffith ◽  
Daniel Andrade ◽  
Anish Babu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Dna Damage ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cells ◽  
Triple Negative

scholarly journals YAP1 inhibition radiosensitizes triple negative breast cancer cells by targeting the DNA damage response and cell survival pathways

Oncotarget ◽  
2017 ◽  
Vol 8 (58) ◽  
pp. 98495-98508 ◽  
Author(s):  
Daniel Andrade ◽  
Meghna Mehta ◽  
James Griffith ◽  
Janani Panneerselvam ◽  
Akhil Srivastava ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Damage ◽  
Cell Survival ◽  
Cancer Cells ◽  
Dna Damage Response ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Survival Pathways ◽  
Damage Response

scholarly journals MUC1-C Integrates Chromatin Remodeling and PARP1 Activity in the DNA Damage Response of Triple-Negative Breast Cancer Cells

2019 ◽  
Vol 79 (8) ◽  
pp. 2031-2041 ◽  
Author(s):  
Masaaki Yamamoto ◽  
Caining Jin ◽  
Tsuyoshi Hata ◽  
Yota Yasumizu ◽  
Yan Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Damage ◽  
Cancer Cells ◽  
Chromatin Remodeling ◽  
Dna Damage Response ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Damage Response
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