Retraction notice to “Sun exposure related methylation in malignant and non-malignant skin lesions” [Cancer Letters 245/1-2 (2007) 112-120]

2018 ◽  
Vol 432 ◽  
pp. 272
Author(s):  
Ubaradka G. Sathyanarayana ◽  
Angela Yen Moore ◽  
Lin Li ◽  
Asha Padar ◽  
Kuntal Majmudar ◽  
...  
Author(s):  
John B. Holds

Chemical peels, mechanical abrasion, and more recently laser and electrosurgical devices are used to resurface eyelid and facial skin. The common feature in these techniques is the denaturation or removal of the skin surface. These techniques typically help to hide skin changes related to sun exposure and aging by evening the skin tone, decreasing dyschromia, and diminishing wrinkles. These techniques all require careful case selection and patient preparation with appropriate treatment and postoperative care. Recent interest has focused on less invasive therapy with techniques that leave the epithelium largely intact, shortening healing time and reducing the risk of complications. Aging and sun damage induce a number of changes in skin, including wrinkling, the development of muscle- or gravity-related folds, irregular pigment or dyschromia, and the growth of benign and malignant skin lesions. Scars from acne, trauma, or surgery can also be indications for skin resurfacing. Potential benefit in all of these techniques must be balanced against risks and expected healing time. A medical history must be obtained, looking for a history of immune dysfunction, prior acne, or a history of herpes simplex outbreaks. Prior treatment with radiation or isotretinoin (Accutane) may diminish the pilosebaceous units required for healing. Acne rosacea and cutaneous telangiectasia may be aggravated by skin resurfacing. Cutaneous history must focus on scarring tendencies such as keloid formation, skin type, and ancestry. In particular, one must determine the patient’s skin type, most commonly by assigning a Fitzpatrick’s skin type. Patients with skin type III require careful topical preparation for skin resurfacing treatment in most cases, and patients with skin type IV or higher are more prone to scarring and pigment issues and are not treated with medium depth to deep skin resurfacing techniques by most clinicians. Wrinkles may be graded by the Glogau classification scheme. This scale from “fine wrinkles” (type 1) to “only wrinkles” (type IV) will help to define the amount and type of treatment needed. These loose recommendations will generally hold true in determining effective therapy. The deeper and more invasive the treatment, the more important the role of skin preparation and prophylaxis.


2020 ◽  
Vol 9 (1) ◽  
pp. 37-42
Author(s):  
David Chapireau ◽  
Saqib J. Bashir ◽  
Kathleen Fan

As part of the holistic approach to their patients, General Dental Practitioners are well placed to identify common skin lesions. Awareness and recognition of worrying lesions allow timely and appropriate referrals for further investigation and treatment. In this paper, we review benign, premalignant and malignant skin lesions, as well as genetic skin conditions. Past medical, family and social history (including sun exposure and previous cutaneous malignancy) is important. Examination includes the lesion, the skin type and the regional lymph nodes. The different common lesions are described, and the epidemiology, clinical features and treatment are discussed. Screening for skin lesions on the head and neck may be undertaken as part of overall dental care as part of the holistic examination of patients. Particularly with precancerous lesions and skin cancer, an early detection and referral from a dentist can expedite treatment and improve prognosis.


2007 ◽  
Vol 245 (1-2) ◽  
pp. 112-120 ◽  
Author(s):  
Ubaradka G. Sathyanarayana ◽  
Angela Yen Moore ◽  
Lin Li ◽  
Asha Padar ◽  
Kuntal Majmudar ◽  
...  

1993 ◽  
Vol 26 (2) ◽  
pp. 215-230
Author(s):  
Gerry F. Funk ◽  
Henry T. Hoffman ◽  
Keith D. Carter
Keyword(s):  

Medicine ◽  
2021 ◽  
Author(s):  
Catherine Drislane ◽  
Katie Lacy
Keyword(s):  

Author(s):  
Maryam M. Asgari ◽  
David J. Leffell
Keyword(s):  

PRiMER ◽  
2021 ◽  
Vol 5 ◽  
Author(s):  
Peggy R. Cyr ◽  
Wendy Craig ◽  
Hadjh Ahrns ◽  
Kathryn Stevens ◽  
Caroline Wight ◽  
...  

Introduction: Early detection of melanoma skin cancer improves survival rates. Training family physicians in dermoscopy with the triage amalgamated dermoscopic algorithm (TADA) has high sensitivity and specificity for identifying malignant skin neoplasms. In this study we evaluated the effectiveness of TADA training among medical students, compared with practicing clinicians. Methods: We incorporated the TADA framework into 90-minute workshops that taught dermoscopy to family physicians, primary care residents, and first- and second-year medical students. The workshop reviewed the clinical and dermoscopic features of benign and malignant skin lesions and included a hands-on interactive session using a dermatoscope. All participants took a 30-image pretest and a different 30-image posttest. Results: Forty-six attending physicians, 25 residents, and 48 medical students participated in the workshop. Mean pretest scores were 20.1, 20.3, and 15.8 for attending physicians, resident physicians and students, respectively (P<.001); mean posttest scores were 24.5, 25.9, and 24.1, respectively (P=.11). Pre/posttest score differences were significant (P<.001) for all groups. The medical students showed the most gain in their pretest and posttest scores. Conclusion: After short dermoscopy workshop, medical students perform as well as trained physicians in identifying images of malignant skin lesions. Dermoscopy training may be a valuable addition to the medical school curriculum as this skill can be used by primary care physicians as well as multiple specialists including dermatologists, gynecologists, otolaryngologists, plastic surgeons, and ophthalmologists, who often encounter patients with concerning skin lesions.


Author(s):  
Ganiyu Oyediran Oseni ◽  
Peter Babatunde Olaitan ◽  
Akinwumi Oluwole ◽  
Olaejirinde Olaniyi Olaofe ◽  
Hezekiah Adebola Morakinyo ◽  
...  
Keyword(s):  

Author(s):  
Aditi Singhal ◽  
Ramesht Shukla ◽  
Pavan Kumar Kankar ◽  
Saurabh Dubey ◽  
Sukhjeet Singh ◽  
...  

Effective diagnosis of skin tumours mainly relies on the analysis of the characteristics of the lesion. Automatic detection of malignant skin lesion has become a mandatory task to reduce the risk of human deaths and increase their survival. This article proposes a study of skin lesion classification using transfer learning approach. The transfer learning model uses four different state-of-the-art architectures, namely Inception v3, Residual Networks (ResNet 50), Dense Convolutional Networks (DenseNet 201) and Inception Residual Networks (Inception ResNet v2). These models are trained under the dataset comprising seven different classes of skin lesions. The skin lesion images are pre-processed using image quantization, grayscaling and the Wiener filter before final training step. These models are compared for performance evaluation on different metrics. The present study shows the efficacy of the methodology for automated classification of lesion images.


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