ASPER-29 suppresses the metastasis of pancreatic cancer cells by dual inhibition of cathepsin-L and cathepsin-S

Chemico-Biological Interactions ◽

10.1016/j.cbi.2022.109811 ◽

2022 ◽

pp. 109811

Author(s):

Lei Yuan ◽

Juanping Zhao ◽

Songkun Zhao ◽

Tianyi Dong ◽

Ruitong Dong ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Cathepsin L ◽

Cathepsin S ◽

Pancreatic Cancer Cells ◽

Dual Inhibition

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Abstract 4982: Characterization of novel α-ketoamide derivatives as potent inhibitors against cathepsin S induced by acidic extracellular pH in pancreatic cancer cells

10.1158/1538-7445.am2014-4982 ◽

2014 ◽

Author(s):

Wun-Shaing Wayne Chang ◽

Tzu-Yuan Chang ◽

Tzu-Chin Wu ◽

Chien-Yu Liao ◽

Chun-Cheng Lin

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Extracellular Ph ◽

Cathepsin S ◽

Pancreatic Cancer Cells ◽

Acidic Extracellular Ph

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15-deoxy-Δ12,14-prostaglandin J2 stimulates cathepsin-L expression in human pancreatic cancer cells through multiple pathways

Gastroenterology ◽

10.1016/s0016-5085(03)81468-3 ◽

2003 ◽

Vol 124 (4) ◽

pp. A292

Author(s):

Guido Eibl ◽

Howard A. Reber ◽

Yuji Okada ◽

John P. Duffy ◽

Oscar J. Hines

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Cathepsin L ◽

Human Pancreatic Cancer ◽

Pancreatic Cancer Cells ◽

Prostaglandin J2

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Upregulated β-catenin signaling does not affect survival of pancreatic cancer cells during dual inhibition of GSK3B and HDAC

Pancreatology ◽

10.1016/j.pan.2019.12.019 ◽

2020 ◽

Vol 20 (3) ◽

pp. 558-561 ◽

Author(s):

Kateryna Nesteruk ◽

Ron Smits ◽

Marco Bruno ◽

Maikel P. Peppelenbosch ◽

Gwenny M. Fuhler

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Pancreatic Cancer Cells ◽

Dual Inhibition

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Dual Inhibition of Topoisomerase II and Tyrosine Kinases by the Novel Bis-Fluoroquinolone Chalcone-Like Derivative HMNE3 in Human Pancreatic Cancer Cells

PLoS ONE ◽

10.1371/journal.pone.0162821 ◽

2016 ◽

Vol 11 (10) ◽

pp. e0162821 ◽

Author(s):

Yong-Chao Ma ◽

Zhi-Xin Wang ◽

Shao-Ju Jin ◽

Yan-Xin Zhang ◽

Guo-Qiang Hu ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Tyrosine Kinases ◽

Topoisomerase Ii ◽

Human Pancreatic Cancer ◽

The Novel ◽

Pancreatic Cancer Cells ◽

Dual Inhibition

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402 Dual Inhibition of the MEK and the PI3K-Akt-mTOR Pathways Using GSK1120212 (or UO126) and Everolimus Overcomes Resistance to MEK Inhibitors Used as Single Agents in Pancreatic Cancer Cells

European Journal of Cancer ◽

10.1016/s0959-8049(12)72200-1 ◽

2012 ◽

Vol 48 ◽

pp. 122

Author(s):

C. Neuzillet ◽

M. Serova ◽

A. Raballand ◽

L. Astorgues-Xerri ◽

M.E. Riveiro ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Mek Inhibitors ◽

Pancreatic Cancer Cells ◽

Dual Inhibition

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Abstract 1198: Neuropilin-1 blockade chemosensitizes pancreatic cancer cells via dual inhibition of epithelial-mesenchymal transition and autophagy

10.1158/1538-7445.am2017-1198 ◽

2017 ◽

Author(s):

Pratiek N. Matkar ◽

Krishna K. Singh ◽

Gerald Prud’homme ◽

David Hedley ◽

Howard Leong-Poi

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Epithelial Mesenchymal Transition ◽

Mesenchymal Transition ◽

Pancreatic Cancer Cells ◽

Neuropilin 1 ◽

Dual Inhibition

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Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells

Molecular Oncology ◽

10.1016/j.molonc.2012.10.013 ◽

2012 ◽

Vol 7 (3) ◽

pp. 369-378 ◽

Author(s):

Sangkil Nam ◽

Wei Wen ◽

Anne Schroeder ◽

Andreas Herrmann ◽

Hua Yu ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Src Family Kinases ◽

Human Pancreatic Cancer ◽

Stat3 Signaling ◽

Pancreatic Cancer Cells ◽

Dual Inhibition

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Synergistic effects of retrovirus IFN-α gene transfer and gemcitabine on apoptosis of pancreatic cancer cells

Gastroenterology ◽

10.1016/s0016-5085(01)83058-4 ◽

2001 ◽

Vol 120 (5) ◽

pp. A615-A615

Author(s):

M GORSCHLUETER ◽

B SCHOETTKER ◽

A MAERTEN ◽

C ZISKE

Keyword(s):

Pancreatic Cancer ◽

Gene Transfer ◽

Cancer Cells ◽

Synergistic Effects ◽

Pancreatic Cancer Cells

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Standardized herbal extracts of Japanese Kampo medicine and their effects on human and murine pancreatic cancer cells

10.1055/s-0039-3399710 ◽

2019 ◽

Author(s):

K Kuchta ◽

K Weimer ◽

L Frank ◽

H Rausch ◽

V Ellenrieder ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Kampo Medicine ◽

Herbal Extracts ◽

Pancreatic Cancer Cells

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IKK1 promotes G1 phase progression of pancreatic cancer cells by the transcriptional regulation of the F-box protein skp2

Zeitschrift für Gastroenterologie ◽

10.1055/s-2005-920118 ◽

2005 ◽

Vol 43 (05) ◽

Author(s):

G Schneider ◽

D Saur ◽

J Siveke ◽

R Fritsch ◽

RM Schmid

Keyword(s):

Pancreatic Cancer ◽

Transcriptional Regulation ◽

Cancer Cells ◽

G1 Phase ◽

Pancreatic Cancer Cells ◽

Phase Progression ◽

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