Role of nutritional vitamin D in osteoporosis treatment

2018 ◽  
Vol 484 ◽  
pp. 179-191 ◽  
Author(s):  
Yi-Chou Hou ◽  
Chia-Chao Wu ◽  
Min-Tser Liao ◽  
Jia-Fwu Shyu ◽  
Chi-Feng Hung ◽  
...  
Keyword(s):  
Vitamin D ◽  
Osteoporosis Treatment ◽  
Nutritional Vitamin

scholarly journals The Emerging Role of Nutritional Vitamin D in Secondary Hyperparathyroidism in CKD

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1890 ◽  
Author(s):  
Chien-Lin Lu ◽  
Dong-Feng Yeih ◽  
Yi-Chou Hou ◽  
Guey-Mei Jow ◽  
Zong-Yu Li ◽  
...  
Keyword(s):  
Vitamin D ◽  
Secondary Hyperparathyroidism ◽  
Fibroblast Growth Factor 23 ◽  
Vitamin D Binding Protein ◽  
Hydroxylase Activity ◽  
Fgf 23 ◽  
Oxyphil Cell ◽  
Pth Level ◽  
Nutritional Vitamin

In chronic kidney disease (CKD), hyperphosphatemia induces fibroblast growth factor-23 (FGF-23) expression that disturbs renal 1,25-dihydroxy vitamin D (1,25D) synthesis; thereby increasing parathyroid hormone (PTH) production. FGF-23 acts on the parathyroid gland (PTG) to increase 1α-hydroxylase activity and results in increase intra-gland 1,25D production that attenuates PTH secretion efficiently if sufficient 25D are available. Interesting, calcimimetics can further increase PTG 1α-hydroxylase activity that emphasizes the demand for nutritional vitamin D (NVD) under high PTH status. In addition, the changes in hydroxylase enzyme activity highlight the greater parathyroid 25-hydroxyvitmain D (25D) requirement in secondary hyperparathyroidism (SHPT); the higher proportion of oxyphil cells as hyperplastic parathyroid progression; lower cytosolic vitamin D binding protein (DBP) content in the oxyphil cell; and calcitriol promote vitamin D degradation are all possible reasons supports nutritional vitamin D (NVD; e.g., Cholecalciferol) supplement is crucial in SHPT. Clinically, NVD can effectively restore serum 25D concentration and prevent the further increase in PTH level. Therefore, NVD might have the benefit of alleviating the development of SHPT in early CKD and further lowering PTH in moderate to severe SHPT in dialysis patients.

The role of vitamin D in metabolic and reproductive disturbances of polycystic ovary syndrome: A narrative mini-review

2020 ◽  
pp. 1-8
Author(s):  
Daniela Menichini ◽  
Gianpiero Forte ◽  
Beatrice Orrù ◽  
Giuseppe Gullo ◽  
Vittorio Unfer ◽  
...  
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Embryo Quality ◽  
Polycystic Ovary ◽  
Vitamin D Supplementation ◽  
Endometrial Receptivity ◽  
Metabolic Disturbances ◽  
Ovary Syndrome ◽  
Beneficial Role

Abstract. Vitamin D is a secosteroid hormone that plays a pivotal role in several metabolic and reproductive pathways in humans. Increasing evidence supports the role of vitamin D deficiency in metabolic disturbances and infertility in women with polycystic ovary syndrome (PCOS). Indeed, supplementation with vitamin D seems to have a beneficial role on insulin resistance and endometrial receptivity. On the other hand, exceedingly high levels of vitamin D appear to play a detrimental role on oocytes development and embryo quality. In the current review, we summarize the available evidence about the topic, aiming to suggest the best supplementation strategy in women with PCOS or, more generally, in those with metabolic disturbances and infertility. Based on the retrieved data, vitamin D seems to have a beneficial role on IR, insulin sensitivity and endometrial receptivity, but high levels and incorrect timing of administration seem to have a detrimental role on oocytes development and embryo quality. Therefore, we encourage a low dose supplementation (400–800 IU/day) particularly in vitamin D deficient women that present metabolic disturbances like PCOS. As far as the reproductive health, we advise vitamin D supplementation in selected populations, only during specific moments of the ovarian cycle, to support the luteal phase. However, ambiguities about dosage and timing of the supplementation still emerge from the clinical studies published to date and further studies are required.

Role of preoperative calcium and vitamin d therapy to prevent postsurgical hypoparathyroidism

2020 ◽  
Author(s):  
Sunghwan SUH ◽  
Park Mi Kyoung ◽  
Kim Duk Kyu ◽  
Kyoungjune Pak
Keyword(s):  
Vitamin D

Vitamin D in trichology: a comprehensive review of the role of vitamin D and its receptor in hair and scalp disorders

2020 ◽  
Vol 155 (2) ◽  
Author(s):  
Giovanni Damiani ◽  
Rosalynn Conic ◽  
Gloria Orlando ◽  
Anna Zampetti ◽  
Elena Marinello ◽  
...  
Keyword(s):  
Vitamin D ◽  
Comprehensive Review

The role of the active metabolite of vitamin D (alfacalcidol) in the treatment of deficiency states and functional disorders

2015 ◽  
Vol 17 (9) ◽  
pp. 139-143
Author(s):  
I.S. Dydykina ◽  
◽  
P.S. Dydykina ◽  
A.A. Kovalenko ◽  
◽  
...  
Keyword(s):  
Vitamin D ◽  
Active Metabolite ◽  
Functional Disorders

The Role of Physical Exercise and Diet in management of Medoroga (STHAULYA) Reference Novel Coronavirus Covid 19

2021 ◽  
Vol 11 (SPL1) ◽  
pp. 1585-1592
Author(s):  
Roshna Sukhdeoji Bhutada
Keyword(s):  
Vitamin D ◽  
Vitamin C ◽  
Physical Movement ◽  
Work From Home ◽  
Causative Factors ◽  
Exercise Routine ◽  
Novel Coronavirus ◽  
Day By Day ◽  
General Wellbeing

Nowadays, due to Covid-19 pandemic circumstance, numerous individuals are Staying from home. Understudy is additionally concern with the online class from home, because of which all physical movement of all individual has been stopped. Medoroga is one of the dominating metabolic problems and driving reason for mortality. Numerous patients with Covid infection 2019 (COVID-19) have identified with the metabolic disorder during the lockdown. The general wellbeing proposes (Work from Home, requests, gyms, terminations of garden and wellness focuses) to forestall Covid-19 spread can possibly decrease day by day physical movement. Ideas of Agni, Prakriti, strategy for victualing ought to be given equivalent consideration while choosing ones dietary and exercise routine to turn away/control Medoroga (STHAULYA). Organizing of diet is generally important to support insusceptibility. According to numerous investigates to give valuable pabulum which contains Zinc, Vitamin C, Vitamin D and invulnerability. It is practically equivalent to Medoroga referenced in Ayurveda compositions. Strick likeness outwardly inspected in both customary arrangement of medication and Ayurveda while portraying its causative components, outcomes and preventive part of exercise and diet in its administration. Striking is outwardly analyzed in both Traditional arrangements of medication and Ayurveda depicting its causative factors, and preventive capacity of movement and diet in its pandemic Covid-19.

SUBLINGUAL VITAMIN D3 DRUG THERAPY IN VITAMIN D DEFICIENCY PATIENTS AT PRAVARA RURAL HOSPITAL

2019 ◽  
pp. 18-20
Author(s):  
Sanjeeva Kumar Goud T ◽  
Rahul Kunkulol
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vitamin D3 ◽  
Serum Vitamin ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Significant Difference ◽  
Before And After

The present study was aimed to study the effect of Sublingual Vitamin D3 on Serum Vitamin D level in Vitamin D deficiency patients. This was a cross-sectional and interventional study. All the Vitamin D deficiency patients of age 18-60years and either gender, willing to participate in the study were included. Patients who had greater than 20 ng/ml were excluded from the study. The total number of participants in our study was 200, out of these 111 males and 89 females, the mean age in our study was 51.07 ± 7.39Yrs. All volunteers were given sublingual vitamin D3 (60,000IU) in six doses every fifteen days of follow up for 3 months. The subject’s serum 25(OH)D levels were estimated before and after the treatment of sublingual vitamin D3. There was a statistically significant difference in serum vitamin D3 level before 16.61±6.71 ng/ml and after 35.80±7.80 ng/ml after treatment with Sublingual Vitamin D3. Six doses of 60,000IU of Vitamin D3 sublingual route having improved the role of serum 25(OH)D levels in the treatment of Vitamin D3 deficiency patients.Keywords: Vitamin D3; Sublingual route

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