scholarly journals Acute and chronic toxicity assessment of benzylpenicillin G residue in heat-treated animal food products

Chemosphere ◽  
2018 ◽  
Vol 202 ◽  
pp. 757-767 ◽  
Author(s):  
Cheng Cui ◽  
Xiang Zhang ◽  
Yang Wang ◽  
Shiying Lu ◽  
Huijun Lu ◽  
...  
2017 ◽  

AbstractThe current level of penicillin use and its persisting residues in livestock is potentially concerning; the toxicity of penicillin residues in heat-treated animal food products (HAFP) is yet to be elucidated. In this study, the acute and chronic toxicity of benzylpenicillin G (BPG) residues in HAFP was investigated in a mouse model. The calculated LD50 of BPG heated to cooking temperature (BPHCT) was 933.04 mg kg-1 [b.w.] intraperitoneally corresponding to 3.75 times lower than its prototype. Mice fed on the experimental diet containing heat-treated beef with high BPG levels for 6 months displayed a reduction in body weight and altered serum values indicating for liver and renal function. Further, the organ ratios of intestinal and spleen were increased. Histopathological changes were observed in the liver, lung and parenchyma testis tissue. BPHCT residue induced sperm aberration and micronucleated polychromatic erythrocytes formation. Present results indicate that prolonged exposure of BPHCT at higher levels of residue might have an impact on public health. Importantly the toxic concentrations of BPHCT are relatively high compared with levels that would result from the degradation of antibiotic residues in meat from animals that have received a therapeutic dose of BPG.


2018 ◽  
Vol 52 (12) ◽  
pp. 2334-2355
Author(s):  
Shona M. Bettany ◽  
Ben Kerrane

PurposeUsing the family activity of hobby stock-keeping (“petstock”) as a context, this paper aims to extend singularization theory to model the negotiations, agencies and resistances of children, parents and petstock, as they work through how animals become food within the boundaries of the family home. In doing so, the authors present an articulation of this process, deciphering the cultural biographies of petstock and leading to an understanding of the emergent array of child animal food-product preferences.Design/methodology/approachData were collected from petstock-keeping parents through a mixture of ethnographic, in-depth interviewing and netnographic engagements in this qualitative, interpretive study; with parents offering experiential insights into animal meat and food-product socialization behaviours played out within the family environments.FindingsThe findings discuss the range of parental behaviours, motivations and activities vis-à-vis petstock, and their children’s responses, ranging from transgression to full compliance, in terms of eating home-raised animal food-products. The discussion illustrates that in the context of petstock, a precocious child food preference agency towards animal meat and food products is reported to emerge.Research limitations/implicationsThis research has empirical and theoretical implications for the understanding of the development of child food preference agency vis-à-vis animal food products in the context of family petstock keeping.Practical implicationsThe research has the potential to inform policy makers around child education and food in regard to how child food preferences emerge and can inform marketers developing food-based communications aimed at children and parents.Originality/valueTwo original contributions are presented: an analysis of the under-researched area of how children’s food preferences towards eating animal food products develop, taking a positive child food-choice agency perspective, and a novel extension of singularization theory, theorizing the radical transformation, from animal to food, encountered by children in the petstock context.


2020 ◽  
Vol 132 ◽  
pp. 69-77
Author(s):  
M.V. Zbrun ◽  
E. Rossler ◽  
A. Romero-Scharpen ◽  
L.P. Soto ◽  
A. Berisvil ◽  
...  

2015 ◽  
Vol 11 (2) ◽  
pp. 153-160 ◽  
Author(s):  
Seung Hyuck Bang ◽  
Ji-Young Ahn ◽  
Nam-Hui Hong ◽  
Simranjeet Singh Sekhon ◽  
Yang-Hoon Kim ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document