scholarly journals TRANSTHORACIC ULTRASOUND-GUIDED NEEDLE ASPIRATION BIOPSY (TUS) IMPROVING LUNG CANCER DIAGNOSIS: HIGH SAFETY AND ACCURACY OF MINIMALLY INVASIVE PROCEDURE

CHEST Journal ◽  
2020 ◽  
Vol 157 (6) ◽  
pp. A255
Author(s):  
A. Del Colle ◽  
C.M.I. Quarato ◽  
M. Venuti ◽  
D. Lacedonia ◽  
L. Dimitri ◽  
...  
2019 ◽  
Vol 27 (6) ◽  
pp. 471-475 ◽  
Author(s):  
Dwight Harris ◽  
Sibu Saha

Purpose Historically, mediastinoscopy has been the gold standard for lung cancer diagnosis and staging, but mediastinoscopy has many limitations including sensitivity, the limited number of lymph node levels that can be sampled, and safety. Endobronchial ultrasound-guided transbronchial needle aspiration is a relatively new and less-invasive technique being used for lung cancer screening. Many studies have reported that it has similar sensitivity and specificity compared to mediastinoscopy, with a significantly lower complication rate. We performed this review to determine our institution’s experience with endobronchial ultrasound-guided transbronchial needle aspiration in lung cancer diagnosis and staging. Methods We reviewed the last 150 patients with suspected lung cancer who underwent endobronchial ultrasound-guided transbronchial needle aspiration procedures in our institution from May 26, 2016 to August 31, 2017. Results Ninety-seven of the 150 patients had a confirmed diagnosis of malignancy. Forty patients had a diagnosis other than cancer, and 13 had incomplete information or were lost to follow-up. Endobronchial ultrasound-guided transbronchial needle aspiration was correct in diagnosing malignancy or excluding malignant lymph nodes in 92 of the 97 patients with malignancy. Overall, the sensitivity, specificity, positive-predictive value, and negative-predictive value was 94.0%, 100.0%, 100.0%, and 91.5%, respectively. Only 3 complications were reported: 2 patients suffered minor bleeding, and one suffered major bleeding that resulted in cardiac arrest. Conclusions Real-time endobronchial ultrasound-guided transbronchial needle aspiration has a similar sensitivity and specificity to mediastinoscopy in diagnosing malignancy, with fewer complications and more financial benefit.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Sukhuma Warrasak ◽  
Sawang Saenghirunvattana ◽  
Ataya Euswas ◽  
Santa Methasiri ◽  
Surapon Worapongpaiboon ◽  
...  

Purpose. To introduce a minimally invasive procedure, endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), to obtain a pathologic evidence of a definite ocular sarcoidosis in a patient who initially presented with presumed ocular sarcoidosis with pulmonary involvement.Methods. An EBUS-TBNA procedure was performed at perihilar lymph nodes, subcarina, and right paratrachea of the patient and specimen obtained was sent for histocytopathological studies.Result. Histocytopathological findings revealed aggregates of epithelioid histiocytes forming a noncaseous granuloma, a hallmark of sarcoidosis.Conclusion. EBUS-TBNA should be considered an alternative procedure to provide cytohistopathology proven diagnosis of definite ocular sarcoidosis.


2007 ◽  
Vol 76 (3) ◽  
pp. 475-485 ◽  
Author(s):  
K. Paclíková ◽  
P. Kohout ◽  
M. Vlašín

In the study conducted on 29 pre-selected patients, we intended to evaluate the reproducibility of prostatic catheter biopsy (CB) as a minimally invasive procedure, directly comparing it to another well-established method, namely ultrasound-guided fine-needle aspiration biopsy (USG-FNAB). As a direct control we used histopathological evaluation and microbial cultivation of samples obtained by percutaneous Tru-Cut biopsy. Evaluating our data, we found that for establishing proper diagnosis by means of cytology, less invasive catheter biopsy (CB 75.86%) is at least comparable to already proven ultrasound-guided fine needle aspiration biopsy (USG-FNAB 72.41%), while catheter biopsy (CB 13 cases out of 29) was significantly (p < 0.0001) more sensitive in actual identification of infectious agents than ultrasound-guided fine needle aspiration biopsy (USG-FNAB 2 cases of 29).We believe that an early microbial evaluation of patients suffering from prostatic disorders helps to target antimicrobial treatment in the beginning of therapy, reducing the risk of failure due to bacterial resistance.


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