MILIARY METASTATIC ADENOCARCINOMA

With the extensive industrial use of asbestos in this century and the long latent period (20-50 years) between exposure and tumor presentation, the incidence of malignant mesothelioma is now increasing. Thus, surgical pathologists are more frequently faced with the dilemma of differentiating mesothelioma from metastatic adenocarcinoma and spindle-cell sarcoma involving serosal surfaces. Electron microscopy is amodality useful in clarifying this problem.In utilizing ultrastructural features in the diagnosis of mesothelioma, it is essential to appreciate that the classification of this tumor reflects a variety of morphologic forms of differing biologic behavior (Table 1). Furthermore, with the variable histology and degree of differentiation in mesotheliomas it might be expected that the ultrastructure of such tumors also reflects a range of cytological features. Such is the case.

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Ultrastructural diagnosis of peritoneal malignant mesothelioma

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100168906 ◽

1994 ◽

Vol 52 ◽

pp. 234-235

Author(s):

S. Siew

Keyword(s):

Malignant Mesothelioma ◽

Common Type ◽

Abdominal Discomfort ◽

The Body ◽

Metastatic Adenocarcinoma ◽

Common Site ◽

Primary Malignancy ◽

Peritoneal Implant ◽

Morphological Diagnosis ◽

Malignant Neoplasia

Mesothelial cells constitute the lining of the three serous sacs of the body i.e. the pleura, pericardium and peritoneum. The more common type of malignant neoplasia of the serous sacs is seeding by metastatic tumors and primary malignancy of the mesothelium is unusual. Of the three sacs, the pleura is the most common site of malignant mesothelioma. Involvement of the peritoneum is extremely rare.We report 3 cases of malignant mesothelioma of the peritoneum. All of them were female. Their ages were 57, 67 and 72 years, respectively. The patients presented with abdominal discomfort and/or ascites. The extent of the tumors ranged from a peritoneal implant to widespread infiltration of the peritoneum and omentum. Histologic examination in Case 1 showed the presence of a diffusely infiltrating papillary mesothelioma without a sarcomatoid component. A mesodermal element was present in the other two cases. In order to establish a morphological diagnosis of malignant mesothelioma, the possibility has to be excluded of a metastatic adenocarcinoma.

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Erythema gyratum repens with metastatic adenocarcinoma

Archives of Dermatology ◽

10.1001/archderm.111.2.227 ◽

1975 ◽

Vol 111 (2) ◽

pp. 227-229 ◽

Cited By ~ 11

Author(s):

M. Skolnick

Keyword(s):

Metastatic Adenocarcinoma

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Cardiac Tamponade As the Initial Manifestation of Metastatic Adenocarcinoma from the Colon: A Case Report

The Heart Surgery Forum ◽

10.1532/hsf98.20071068 ◽

2007 ◽

Vol 10 (4) ◽

pp. E329-E330 ◽

Cited By ~ 5

Author(s):

Jia-Lin Chen ◽

Tsai-Wang Huang ◽

Po-Shun Hsu ◽

MD Chao-Yang, ◽

Chien-Sung Tsai

Keyword(s):

Case Report ◽

Cardiac Tamponade ◽

Metastatic Adenocarcinoma ◽

Initial Manifestation

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Metastatic Adenocarcinoma lung Mimicking Spinal Tuberculosis (Pott's disease) in a female Presenting with Spinal Cord Compression

International Journal of Scientific Research ◽

10.15373/22778179/july2013/115 ◽

2012 ◽

Vol 2 (7) ◽

pp. 338-339

Author(s):

Dr.Umang Agrawal ◽

◽

Dr. Sujata Tripathi

Keyword(s):

Spinal Cord ◽

Spinal Cord Compression ◽

Spinal Tuberculosis ◽

Cord Compression ◽

Metastatic Adenocarcinoma ◽

Pott’S Disease

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Risk factors and predictors for tumor site origin in metastatic adenocarcinoma of unknown primary site

Cancer Medicine ◽

10.1002/cam4.3684 ◽

2021 ◽

Author(s):

Xinrong Li ◽

Yan Shao ◽

Liqiang Sheng ◽

Junquan Zhu ◽

Zeming Wang ◽

...

Keyword(s):

Risk Factors ◽

Primary Site ◽

Unknown Primary ◽

Tumor Site ◽

Metastatic Adenocarcinoma ◽

Unknown Primary Site

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Duodenal adenocarcinoma with skin metastasis as initial manifestation: A case report

Open Life Sciences ◽

10.1515/biol-2021-0029 ◽

2021 ◽

Vol 16 (1) ◽

pp. 395-398

Author(s):

Yixiao Fu ◽

Cuiping Zheng ◽

Jian Huang ◽

Shenghao Wu ◽

Yanyan Dai

Keyword(s):

Oral Treatment ◽

Duodenal Biopsy ◽

Skin Metastasis ◽

Metastatic Adenocarcinoma ◽

Duodenal Adenocarcinoma ◽

Initial Manifestation ◽

Case Presentation ◽

Replacement Treatment ◽

Lost To Follow Up

Abstract Background Duodenal adenocarcinoma (DA) with skin metastasis as initial manifestation is clinically rare. In this study, we report a rare case of skin metastasis of DA. Case presentation An 84-year-old male patient developed multiple ecchymoses on the trunk and lower extremities. Physical examination showed that the ecchymosis was dark red and had a hard texture, but showed no bulging, rupture, or tenderness. The skin biopsy implied skin metastatic adenocarcinoma. After an endoscopic duodenal biopsy, the patient was finally diagnosed with DA with skin metastasis. The patient received two courses of oral treatment of Tegafur (40 mg, bid d1–d14). However, the patient stopped taking Tegafur because of its poor effect and received Chinese medicine as a replacement treatment. Unfortunately, he was lost to follow-up. Conclusions Early diagnosis of DA metastasis is of significant importance as prognosis of these patients is poor.

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