Definitive Chemoradiotherapy for Locally Advanced, Lymph-node Positive, Nonmetastatic Penile Squamous Cell Carcinoma

2020 ◽  
Vol 18 (5) ◽  
pp. e573-e584
Author(s):  
Kyra McComas ◽  
Neeraj Agarwal ◽  
Glen Bowen ◽  
Benjamin L. Maughan ◽  
Jonathan D. Tward
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Locally Advanced ◽  
Definitive Chemoradiotherapy ◽  
Node Positive ◽  
Lymph Node Positive ◽  
Penile Squamous Cell Carcinoma

scholarly journals Interleukin-4 mRNA Expression in Laryngeal Squamous Cell Carcinoma Patients with or without Lymph Node Involvement

2014 ◽  
Vol 3 (1) ◽  
pp. 20-23
Author(s):  
Esmael Amirazodi ◽  
Mahboobeh Razmkhah ◽  
Mansoureh Jaberipour ◽  
Ahmad Hosseini ◽  
Bijan Khademi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Mrna Expression ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Lymph Node Involvement ◽  
Interleukin 4 ◽  
Node Positive ◽  
Lymph Node Positive

Background: Interleukin (IL)-4 is a member of T helper 2 (Th2) axis produced by T-lymphocyte and mast cell. It has been shown that IL-4 expression changes in tumor tissues. The main objective of this study is to investigate the expression of IL-4 mRNA in patients with Laryngeal Squamous Cell Carcinoma (LSCC) with or without lymph node involvement.Materials and Methods: mRNA expression of IL-4 in LSCC tissues were detected by quantative Real-Time PCR (qRT-PCR). Expression of IL-4 gene was compared between lymph node positive and negative patients with Squamous Cell Carcinoma of Larynx.Results: No statistically significant association was found in expression of IL-4 between lymph node positive and negative patients. Conclusion: It seems that IL-4 has no important effect on the involvement of lymph node in LSCC. However, to achieve a definite conclusion more investigations are certainly required.

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