Effects of body acupuncture versus auricular acupuncture on anthropometric, lipid profile, inflammatory and immunologic markers: a randomized controlled trial study

Abstract Background Exercise is a well-accepted strategy to improve lipid and inflammatory profile in individuals with type 2 diabetes (T2DM). However, the exercise intensity having the most benefits on lipids and inflammatory markers in patients with T2DM remains unclear. We aimed to analyse the impact of a 1-year combined high-intensity interval training (HIIT) with resistance training (RT), and a moderate continuous training (MCT) with RT on inflammatory and lipid profile in individuals with T2DM. Methods Individuals with T2DM (n = 80, aged 59 years) performed a 1-year randomized controlled trial and were randomized into three groups (control, n = 27; HIIT with RT, n = 25; MCT with RT, n = 28). Exercise sessions were supervised with a frequency of 3 days per week. Inflammatory and lipid profiles were measured at baseline and at 1-year follow-up. Changes in inflammatory and lipid markers were assessed using generalized estimating equations. Results After adjusting for sex, age and baseline moderate-to-vigorous physical activity (MVPA), we observed a time-by-group interaction for Interleukin-6 (IL-6) in both the MCT with RT (β = − 0.70, p = 0.034) and HIIT with RT (β = − 0.62, p = 0.049) groups, whereas, only the HIIT with RT group improved total cholesterol (β = − 0.03, p = 0.045) and LDL-C (β = − 0.03, p = 0.034), when compared to control. No effect was observed for C-reactive protein (CRP), cortisol, tumour necrosis factor-α (TNF-α), soluble form of the haptoglobin-hemoglobin receptor CD163 (sCD163), triglycerides and HDL-C in both groups (p > 0.05). Conclusions Favorable adaptations on IL-6 were observed in both the HIIT and MCT combined with RT groups following a long-term 1-year exercise intervention in individuals with T2DM. However, only the HIIT with RT prevented further derangement of total cholesterol and LDL-C, when compared to the control group. Therefore, in order to encourage exercise participation and improve inflammatory profile, either exercise protocols may be prescribed, however, HIIT with RT may have further benefits on the lipid profile. Trial registration Clinicaltrials.gov ID: NCT03144505

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Water-Based Aerobic and Resistance Training as a Treatment to Improve the Lipid Profile of Women With Dyslipidemia: A Randomized Controlled Trial

Journal of Physical Activity and Health ◽

10.1123/jpah.2018-0602 ◽

2019 ◽

Vol 16 (5) ◽

pp. 348-354 ◽

Cited By ~ 2

Author(s):

Rochelle R. Costa ◽

Adriana C.K. Buttelli ◽

Leandro Coconcelli ◽

Laura F. Pereira ◽

Alexandra F. Vieira ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Resistance Training ◽

Lipid Profile ◽

Controlled Trial ◽

Randomized Controlled ◽

Water Based

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Weight and Abdominal Adiposity Loss with Auricular Acupuncture – A Randomized Controlled Trial

10.33696/pathology.2.022 ◽

2021 ◽

Vol 2 (3) ◽

Keyword(s):

Randomized Controlled Trial ◽

Controlled Trial ◽

Auricular Acupuncture ◽

Abdominal Adiposity ◽

Randomized Controlled

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Impact of Combined Training with Different Exercise Intensities on Inflammatory and Lipid Markers in Type 2 Diabetes: A Secondary Analysis from a 1-Year Randomized Controlled Trial

10.21203/rs.3.rs-36837/v1 ◽

2020 ◽

Author(s):

João P. Magalhães ◽

Diana A. Santos ◽

Inês R. Correia ◽

Megan Hetherington-Rauth ◽

Rogério Ribeiro ◽

...

Keyword(s):

Type 2 Diabetes ◽

Randomized Controlled Trial ◽

Lipid Profile ◽

Total Cholesterol ◽

Controlled Trial ◽

Soluble Form ◽

Randomized Controlled ◽

Lipid Markers ◽

Inflammatory Profile

Abstract Background: Exercise is a well-accepted strategy to improve lipid and inflammatory profile in individuals with type 2 diabetes (T2DM). However, the exercise intensity having the most benefits on lipids and inflammatory markers in patients with T2DM remains unclear. We aimed to analyse the impact of a 1-year combined high-intensity interval training (HIIT) with resistance training (RT), and a moderate continuous training (MCT) with RT on inflammatory and lipid profile in individuals with T2DM.Methods: Individuals with T2DM (n=80, aged 59 years) performed a 1-year randomized controlled trial and were randomized into three groups (control, n= 27; HIIT with RT, n=25; MCT with RT, n=28). Exercise sessions were supervised with a frequency of 3 days per week. Inflammatory and lipid profiles were measured at baseline and at 1-year follow-up. Changes in inflammatory and lipid markers were assessed using generalized estimating equations. Results: After adjusting for sex, age and baseline moderate-to-vigorous physical activity (MVPA), circulating levels of Interleukin-6 (IL-6) decreased for both the MCT with RT (β=-0.70, p=0.034) and HIIT with RT (β=-0.62, p=0.049) groups, whereas, only the HIIT with RT group improved total cholesterol (β=-0.03, p=0.045) and LDL-C (β=-0.03, p=0.034), when compared to control. No effect was observed for C-reactive protein (CRP), cortisol, tumour necrosis factor-α (TNF-α), soluble form of the haptoglobin-hemoglobin receptor CD163 (sCD163), triglycerides and HDL-C in both groups (p>0.05).Conclusions: Favorable adaptations on IL-6 were observed in both the HIIT and MCT combined with RT groups following a long-term 1-year exercise intervention in individuals with T2DM. However, the HIIT with RT group improved to a greater extent the values of total cholesterol and LDL-C, when compared to the MCT with RT group. Therefore, in order to encourage exercise participation and improve inflammatory profile, either exercise protocols may be prescribed, however, HIIT with RT may have further benefits on the lipid profile.Trial registration: clinicaltrials.gov ID:NCT03144505

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Diabetic yoga protocol improves glycemic, anthropometric and lipid levels in high risk individuals for diabetes: a randomized controlled trial from Northern India

Diabetology & Metabolic Syndrome ◽

10.1186/s13098-021-00761-1 ◽

2021 ◽

Vol 13 (1) ◽

Author(s):

Navneet Kaur ◽

Vijaya Majumdar ◽

Raghuram Nagarathna ◽

Neeru Malik ◽

Akshay Anand ◽

...

Keyword(s):

Randomized Controlled Trial ◽

High Risk ◽

Lipid Profile ◽

Profile Analysis ◽

Controlled Trial ◽

Diabetes Risk ◽

Control Group ◽

Lipid Levels ◽

Randomized Controlled ◽

Northern India

Abstract Purpose To study the effectiveness of diabetic yoga protocol (DYP) against management of cardiovascular risk profile in a high-risk community for diabetes, from Chandigarh, India. Methods The study was a randomized controlled trial, conducted as a sub study of the Pan India trial Niyantrita Madhumeha Bharath (NMB). The cohort was identified through the Indian Diabetes Risk Scoring (IDRS) (≥ 60) and a total of 184 individuals were randomized into intervention (n = 91) and control groups (n = 93). The DYP group underwent the specific DYP training whereas the control group followed their daily regimen. The study outcomes included changes in glycemic and lipid profile. Analysis was done under intent-to-treat principle. Results The 3 months DYP practice showed diverse results showing glycemic and lipid profile of the high risk individuals. Three months of DYP intervention was found to significantly reduce the levels of post-prandial glucose levels (p = 0.035) and LDL-c levels (p = 0.014) and waist circumference (P = 0.001). Conclusion The findings indicate that the DYP intervention could improve the metabolic status of the high-diabetes-risk individuals with respect to their glucose tolerance and lipid levels, partially explained by the reduction in abdominal obesity. The study highlights the potential role of yoga intervention in real time improvement of cardiovascular profile in a high diabetes risk cohort. Trial registration: CTRI, CTRI/2018/03/012804. Registered 01 March 2018—Retrospectively registered, http://www.ctri.nic.in/CTRI/2018/03/012804.

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