The effect of renal dysfunction on short-term outcomes after lumbar fusion

Objective: To evaluate the short-term renal function in neonates with twin anemia-polycythemia sequence (TAPS). Methods: All consecutive monochorionic twins with TAPS with double survivors admitted to three European centers were included in this retrospective study. Each twin pair was matched for gestational age at birth with a control twin pair unaffected by TAPS or twin-twin transfusion syndrome. Creatinine and urea levels in the first week after birth were recorded. Short-term postnatal renal dysfunction was defined as creatinine >100 μmol/l during the first week after birth. Results: A total of 52 TAPS twin pairs and 52 control twin pairs with a median gestational age of 31 weeks at birth were included in the study. In the TAPS group, donors had higher mean creatinine levels compared to recipients, 85 versus 71 μmol/l, respectively (p = 0.001). Short-term renal dysfunction was detected in 26.0% (13/50) of the donors versus 6.3% (3/48) of the recipients (p = 0.022). In the control group, no inter-twin differences in creatinine levels were found. Conclusions: Donor twins with TAPS have higher creatinine levels than recipient twins, suggesting that chronic inter-twin transfusion in TAPS may also cause short-term renal dysfunction. Long-term renal consequences in TAPS donors require further investigation.

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Comparison of Short-term Outcomes After Lumbar Fusion Between an Orthopedic Specialty Hospital and Tertiary Referral Center

Spine ◽

10.1097/brs.0000000000002911 ◽

2019 ◽

Vol 44 (9) ◽

pp. 652-658

Author(s):

Tyler M. Kreitz ◽

Daniel Tarazona ◽

Eric M. Padegimas ◽

Carol Foltz ◽

Christopher K. Kepler ◽

...

Keyword(s):

Lumbar Fusion ◽

Tertiary Referral ◽

Short Term ◽

Tertiary Referral Center ◽

Referral Center ◽

Specialty Hospital

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Impact of initial 24-h urine output on short-term outcomes in patients with ST-segment elevation myocardial infarction admitted without cardiogenic shock and renal dysfunction

Atherosclerosis ◽

10.1016/j.atherosclerosis.2015.03.005 ◽

2015 ◽

Vol 240 (1) ◽

pp. 137-143

Author(s):

Bi Huang ◽

Yanmin Yang ◽

Jun Zhu ◽

Yan Liang ◽

Huiqiong Tan ◽

...

Keyword(s):

Myocardial Infarction ◽

Cardiogenic Shock ◽

Renal Dysfunction ◽

Urine Output ◽

Short Term ◽

St Segment Elevation ◽

Segment Elevation Myocardial Infarction ◽

St Segment

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Mild and moderate renal dysfunction: impact on short-term outcome

European Journal of Cardio-Thoracic Surgery ◽

10.1016/j.ejcts.2007.04.032 ◽

2007 ◽

Vol 32 (2) ◽

pp. 286-290 ◽

Cited By ~ 6

Author(s):

Caterina Simon ◽

Remo Luciani ◽

Fabio Capuano ◽

Antonio Miceli ◽

Antonino Roscitano ◽

...

Keyword(s):

Renal Dysfunction ◽

Short Term ◽

Term Outcome ◽

Short Term Outcome

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Frequency, pattern and short-term outcome of chronic renal dysfunction in patients with cirrhosis

European Journal of Gastroenterology & Hepatology ◽

10.1097/meg.0000000000000173 ◽

2014 ◽

Vol 26 (11) ◽

pp. 1296-1299 ◽

Cited By ~ 2

Author(s):

Shamila T. De Silva ◽

Ruwan P. Perera ◽

Madunil A. Niriella ◽

Arunasalam Pathmeswaran ◽

Hithanadura Janaka de Silva

Keyword(s):

Renal Dysfunction ◽

Short Term ◽

Frequency Pattern ◽

Term Outcome ◽

Short Term Outcome

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Adult skeletal muscle stem cells differentiate into endothelial lineage and ameliorate renal dysfunction after acute ischemia

AJP Renal Physiology ◽

10.1152/ajprenal.00126.2004 ◽

2004 ◽

Vol 287 (4) ◽

pp. F621-F627 ◽

Cited By ~ 49

Author(s):

Maria Arriero ◽

Sergey V. Brodsky ◽

Olga Gealekman ◽

Paul A. Lucas ◽

Michael S. Goligorsky

Keyword(s):

Skeletal Muscle ◽

Stem Cells ◽

Endothelial Cells ◽

Renal Function ◽

Renal Dysfunction ◽

Renal Ischemia ◽

Short Term ◽

Renal Microvasculature ◽

Endothelial Lineage

We previously demonstrated that endothelial cells are severely damaged during renal ischemia-reperfusion and that transplantation of adult human endothelial cells into athymic nude rats subjected to renal ischemia resulted in a dramatic protection of the kidney against injury and dysfunction. Morphological studies demonstrated the engraftment of transplanted cells into renal microvasculature. The goal of the present study was to determine the potential efficacy of in vitro expanded skeletal muscle-derived stem cells (MDSC) differentiated along the endothelial lineage in ameliorating acute renal injury. MDSC obtained from the Tie-2-green fluorescent protein (GFP) mice were used as donors of differentiated and nondifferentiated stem cells. FVB mice, used as recipients, were subjected to renal ischemia and transplanted with the above MDSC. The differentiation of MDSC along the endothelial lineage was monitored by the appearance of Tie-2 promotor-driven expression of GFP. These mouse endothelial cell antigen-, endothelial nitric oxide synthase (eNOS)-, Flk-1-, Flt-1-, and CD31-positive cells engrafted into renal microvasculature and significantly protected short-term renal function after ischemia. Transplantation of nondifferentiated MDSC characterized by the expression of Sca-1 (low levels of CD34, Flk-1, and cKit, and negative for GFP, eNOS, and CD31) did not improve short-term renal dysfunction. In conclusion, the data 1) provide a rich source of MDSC, 2) delineate protocols for their in vitro expansion and differentiation along the endothelial lineage, and 3) demonstrate their efficacy in preserving renal function immediately after ischemic insult.

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Assessment of renal dysfunction improves troponin-based short-term prognosis in patients with acute symptomatic pulmonary embolism

Journal of Thrombosis and Haemostasis ◽

10.1111/j.1538-7836.2010.03762.x ◽

2010 ◽

Vol 8 (4) ◽

pp. 651-658 ◽

Cited By ~ 22

Author(s):

M. KOSTRUBIEC ◽

A. ŁABYK ◽

J. PEDOWSKA-WŁOSZEK ◽

S. PACHO ◽

A. WOJCIECHOWSKI ◽

...

Keyword(s):

Pulmonary Embolism ◽

Renal Dysfunction ◽

Short Term ◽

Symptomatic Pulmonary Embolism

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Increased Short-Term and Mid-Term Major Complications Were Observed in Elderly Patients with Renal Dysfunction after Surgical Ventricular Restoration

The Heart Surgery Forum ◽

10.1532/hsf.1911 ◽

2018 ◽

Vol 21 (3) ◽

pp. 194

Author(s):

Fei Xu ◽

Yangwu Song ◽

Wei Feng ◽

Xuan Li ◽

Junzhe Du

Keyword(s):

Renal Function ◽

Elderly Patients ◽

Renal Dysfunction ◽

Normal Renal Function ◽

P Value ◽

Short Term ◽

Surgical Ventricular Restoration ◽

Function Group ◽

The Impact ◽

Ventricular Restoration

Background: This study was conducted to explore the impact of renal dysfunction on short-term and mid-term outcomes in elderly patients.Methods: Patients over 65 years of age receiving surgical ventricular restoration (SVR) were included in the study. They were stratified through estimated glomerular filtration rate (eGFR), with a cutoff point of 60 mL/min/1.73m2. Risk-adjusted analysis, including propensity score matching, was carried out to compare short-term and mid-term outcomes between the two groups of patients.Results: From January 1999 to December 2015, a total of 280 elderly patients underwent SVR. Of the patients, 79 had eGFR lower than 60 mL/min/1.73m2 and were considered to have renal dysfunction. Mortality was higher in the renal dysfunction group than the normal renal function group, with marginal significance (adjusted P value = .06). The need for mechanical supports (adjusted P value = .04) was higher in the renal dysfunction group. Hemofiltration (adjusted P value < .01) and requirements for transfusion (adjusted P value = .03) were significantly higher in the renal dysfunction group than in the group with normal renal function. The presence of renal dysfunction was associated with higher risk of major adverse cerebro-cardiovascular events (MACCE) than normal renal function (HR = 2.34, 95% CI = 1.34 - 4.08, P = .003).Conclusion: Compared to patients with normal renal function, elderly SVR patients with renal failure have a higher incidence of short-term mechanical support, mid-term mortality, and MACCE events.

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