P 49. Change in cross-sectional area of the median nerve with age in neonates, infants and children analyzed by high-resolution ultrasound imaging

2021 ◽  
Vol 132 (8) ◽  
pp. e21-e22
Author(s):  
P.J. Broser ◽  
J. Lütschg ◽  
C. Jenny
Keyword(s):  
High Resolution ◽  
Median Nerve ◽  
Ultrasound Imaging ◽  
Cross Sectional Area ◽  
Infants And Children ◽  
Sectional Area ◽  
Cross Sectional

scholarly journals Analysis of the increase in cross-sectional area of the median nerve and its relation to age in neonates, infants and children using high-resolution ultrasound imaging

2020 ◽  
Author(s):  
Carole Jenny ◽  
Jürg Lütschg ◽  
Philip J. Broser
Keyword(s):  
High Resolution ◽  
Median Nerve ◽  
Cross Sectional Study ◽  
Cross Sectional Area ◽  
Infants And Children ◽  
Normative Values ◽  
Ultrasound Images ◽  
List Type ◽  
Sectional Area ◽  
Cross Sectional

ABSTRACTAIMTo analyze the increase in the cross-sectional area (CSA) of the median nerve during early childhood.METHODThis prospective, cross-sectional study used high-resolution ultrasound images of the median nerve from three locations (wrist, forearm and upper arm). A total of 43 participants (32 of whom were children younger than 2 years) were included in the study.RESULTSA strong and highly significant correlation was found between age and CSA (r = 0.8, p < 0.0001). The growth rate of CSA decreases with age. The increase in CSA follows a logarithmic growth curve (p < 0.0001). Based on the regression analysis, an age-synchronous increase in CSA for all three locations was found. The nerve reaches 70% of its final CSA by 2 years of age.INTERPRETATIONSimilar to the nerve conduction speed, the increase in CSA is greatest during the first 2 years of life. Then, the rate gradually and synchronously slows at the proximal and distal locations.What this paper adds-Normative values for increased cross-sectional area (CSA) of the median nerve.-Standardized locations and image procedures outlined for the clinical setting.-Growth dynamic of the CSA of the median nerve in children.-Normative data for development of the median nerve in children.-High resolution ultrasound images of the maturating median nerve in neonates, infants and children.

scholarly journals Role of High-Resolution Ultrasonography in Evaluation of Median Nerve and Thickness of Flexor Retinaculum in Patients with Hypothyroidism

2020 ◽  
Vol 2 ◽  
pp. 36-43
Author(s):  
Kunwar Pal Singh ◽  
Kamlesh Gupta ◽  
Iqbaljit Kaur ◽  
Vijinder Arora
Keyword(s):  
High Resolution ◽  
Healthy Volunteers ◽  
Median Nerve ◽  
Cross Sectional Area ◽  
Width Ratio ◽  
Sectional Area ◽  
Cross Sectional ◽  
Flexor Retinaculum ◽  
Nerve Fascicle ◽  
High Resolution Ultrasonography

Objectives: To determine the role of high resolution ultrasonography in evaluation of cross sectional area, maximum nerve fascicle thickness and thickness/width ratio of the median nerve and flexor retinaculum thickness in patients with hypothyroidism and to correlate it with the healthy volunteers. Material and Methods: A prospective study was conducted from February 2018 to October 2019 on 62 patients which included 32 clinically proven cases of hypothyroidism and 30 healthy volunteers. High resolution ultrasonography was performed using high frequency linear probes. Results: The most affected parameter was cross sectional area of median nerve at three levels, inlet/outlet ratio of CSA of the median nerve and thickness of flexor retinaculum in hypothyroidism patients in correlation with healthy volunteers. These parameters showed statistically significant p values. Maximum nerve fascicle thickness and thickness/width ratio of the median nerve showed no statistical significance in hypothyroid patients in correlation with healthy volunteers. Conclusion: High-resolution ultrasonography plays an important role in evaluating the changes occuring in cross sectional area of the median nerve, its inlet/outlet CSA ratio and flexor retinaculum thickness in hypothyroidism patients as correlated with the healthy volunteers.

scholarly journals Ultrasound Assessment of the Median Nerve Does Not Adequately Discriminate the Carpal Tunnel Syndrome among Patients Diagnosed with Diabetes

Diabetology ◽  
2021 ◽  
Vol 2 (4) ◽  
pp. 226-231
Author(s):  
Carlos Antonio Guillen-Astete ◽  
Monica Luque-Alarcon ◽  
Nuria Garcia-Montes
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Cross Sectional Area ◽  
Diabetic Patients ◽  
Sectional Area ◽  
Cross Sectional ◽  
Patients With Diabetes ◽  
Ultrasound Assessment ◽  
Tunnel Syndrome

Background: Carpal tunnel syndrome is the most prevalent peripheral nerve entrapment condition of the upper limb. Among metabolic risk factors, diabetes is considered the most relevant. Although wrist ultrasound assessment of the median nerve has demonstrated a good correlation with the gold standard for the diagnosis of this syndrome, neurophysiological study, its usefulness in patients with diabetes is questionable because the compressive phenomenon is not the predominant one. Method: We conducted a retrospective study to compare the clinical and median nerve ultrasound features of patients with carpal tunnel syndrome previously diagnosed or not diagnosed with diabetes. Additionally, a linear multivariate regression analysis was performed to determine to what extent the cross-sectional area of the median nerve was dependent on the condition of diabetes by fixing other variables such as sex, age, or time of evolution. Results: We included 303 records of patients (mean age 44.3 ± 11.7 years old, 57.89% female, mean of time of evolution 13.6 ± 8.3 months) from 2012 to 2020. The cross-sectional area of the median nerve was 10.46 ± 1.44 mm2 in non-diabetic patients and 8.92 ± 0.9 mm2 in diabetic patients (p < 0.001). Additionally, diabetic patients had a shorter time of evolution (7.91 ± 8.28 months vs. 14.36 ± 0.526 months, p < 0.001). In the multivariate analysis, the resultant model (fixed R-square = 0.659, p = 0.003) included a constant of the following four variables: the evolution time (Beta coeff. = 0.108, p < 0.001 95% CI 0.091 to 0.126, standardized coeff. = 0.611), the condition of diabetes (Beta coeff. = −0.623, p < 0.001 95% CI −0.907 to −0.339, standardized coeff. = −0.152), the severity (Beta coeff. = 0.359, p = 0.001 95% CI 0.147 to 0.571, standardized coeff. = 0.169), and the masculine sex (Beta coeff. = 0.309, p = 0.003, 95% CI 0.109 to 0.509, standardized coeff. = 0.103). Conclusions: Ultrasound assessment of the median nerve in patients with diabetes is not a useful tool to confirm whether carpal tunnel syndrome should be diagnosed or not diagnosed.

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