scholarly journals Establishing a Link Between Commonly Reported Toxicities and Tumour Location in Brain Tumour Patients Treated With Volumetric-modulated Arc Radiotherapy

2021 ◽  
Vol 33 (1) ◽  
pp. e97-e98
Author(s):  
S. Fernandez ◽  
M. Beasley ◽  
J. Lilley ◽  
L. Murray ◽  
S.C. Short
Brain ◽  
2014 ◽  
Vol 137 (9) ◽  
pp. 2532-2545 ◽  
Author(s):  
Fabio Campanella ◽  
Tim Shallice ◽  
Tamara Ius ◽  
Franco Fabbro ◽  
Miran Skrap

2020 ◽  
Vol 9 (3) ◽  
pp. 91-96
Author(s):  
Agnieszka Królikowska ◽  
◽  
Piotr Zieliński ◽  
Marek Harat ◽  
Renata Jabłońska ◽  
...  

Introduction. The location of intracranial neoplasms and the process of treating these lesions itself can significantly affect the quality of life of patients. Hence, the aim of the study was to investigate the impact of the location of the brain tumour on the quality of life of surgically treated patients. Aim. The aim of the study was to investigate the influence of the location of the brain tumour on the quality of life of surgically treated patients. Material and Methods. The study included 236 patients with brain tumours operated at the Department of Neurosurgery of the 10th Military Clinical Hospital with the SP ZOZ Polyclinic in Bydgoszcz. Patients with different tumour locations were included: in the temporal lobe, in the frontal lobe, in the parietal lobe, in the ventricles of the brain and in the extra-cerebral locations. The following questionnaires were used to assess the quality of life: EORTC QLQ-C30 and EORTC QLQ-BN20, in which the patients were tested three times: on the day of admission to the Clinic, on the fifth day after brain tumour surgery and 30 days after the surgery. Results. Patients’ quality of life decreased in the early postoperative period in all groups in terms of tumour location, especially in patients with tumours of the frontal lobe (-0.104) and ventricular neoplasms (-0.109) (p > 0.05). On the 30th day, however, an improvement in the quality of life was achieved in all groups, the highest improvement was obtained in patients with tumours located extra-cerebrally (0.115) and tumours of the temporal lobe (0.097) (p > 0.05). Conclusions. There was no effect of the location of the brain tumour on the quality of life of the studied patients. In the early postoperative period, the quality of life decreased, while it improved 30 days after the surgery. (JNNN 2020;9(3):91–96) Key Words: brain tumour, quality of life, tumour location


Impact ◽  
2021 ◽  
Vol 2021 (8) ◽  
pp. 19-21
Author(s):  
Sachie Kusaka

Boron neutron capture therapy (BNCT) has the potential to kill tumours without harming normal cells and could therefore prove revolutionary in cancer treatment. BNCT is a treatment that focuses on how the chemical element boron has a high likelihood of causing nuclear reactions with neutrons. A key focus for some researchers is the idea that the nuclear reaction of boron occurs in proportion to the number of optimal energy neutrons and the concentration of boron at the tumour location and they believe that if this could be properly harnessed, the treatment would be dramatically improved. Dr Sachie Kusaka, Graduate School of Engineering, Osaka University, Japan, is part of a team of researchers working to improve the effectiveness of BNCT for brain tumour. Kusaka has identified an alternative route to deliver the boron drug BPA efficiently to the brain by avoiding the blood-brain barrier, and named the route "boron cerebrospinal fluid administration method". "Administering the drug into the cerebrospinal fluid could enable more boron to be efficiently delivered to the brain tumour,' says Kusaka.


2011 ◽  
Vol 223 (06) ◽  
Author(s):  
J Bode ◽  
A Sabag ◽  
S Kietz ◽  
G Neufeld ◽  
M Lakomek

2018 ◽  
Vol 3 (2) ◽  

There have been a few case reports of head injury leading to brain tumour development in the same region as the brain injury. Here we report a case where the patient suffered a severe head injury with contusion. He recovered clinically with conservative management. Follow up Computed Tomography scan of the brain a month later showed complete resolution of the lesion. He subsequently developed malignant brain tumour in the same region as the original contusion within a very short period of 15 months. Head injury patients need close follow up especially when severe. The link between severity of head injury and malignant brain tumour development needs further evaluation. Role of anti-inflammatory agents for prevention of post traumatic brain tumours needs further exploration.


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