Background: Tea (Camellia sinensis, Theaceae) is the second most consumed beverage in
the world. Green tea is the least processed and thus contain rich antioxidant level, and believed to
have most of the health benefits.
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Methods: We commenced to search bibliographic collection of peer reviewed research articles and
review articles to meet the objective of this study.
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Results: From this study, we found that the tea beverage contains catechins are believed to have a
wide range of health benefits which includes neuroprotective, anti-inflammatory, antiulcer, antiviral,
antibacterial, and anti-parasitic effects. The four major catechin compounds of green tea are epigallocatechin
(EGC), epicatechin (EC), epigallocatechin gallate (EGCG), and epicatechin gallate (ECG), of
which EGCG is the major constituent and representing 50-80% of the total catechin content. And also
contain xanthine derivatives such as caffeine, theophylline, and theobromine, and the glutamide derivative
theanine. It also contains many nutritional components, such as vitamin E, vitamin C, fluoride,
and potassium. We sum up the various green tea phytoconstituents, extraction methods, and its
medicinal applications.
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Conclusion: In this review article, we have summarized the pharmacological importance of green tea
catechin which includes antioxidant potential, anti-inflammatory, antimicrobial, anticancer, antidiabetic
and cosmetic application.
EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression
