Computational modeling of nasal nitric oxide flux from the paranasal sinuses: validation against human experiment

2021 ◽  
pp. 104723
Author(s):  
Barak M. Spector ◽  
Dennis J. Shusterman ◽  
Andrew N. Goldberg ◽  
Edward M. Weaver ◽  
Alexander A. Farag ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Computational Modeling ◽  
Paranasal Sinuses ◽  
Nasal Nitric Oxide ◽  
Oxide Flux

scholarly journals Eosinophilic inflammation of the paranasal sinuses and reduced nasal nitric oxide levels in patients with chronic rhinosinusitis

2018 ◽  
Vol 141 (2) ◽  
pp. AB270
Author(s):  
Kanako Yoshida ◽  
Tetsuji Takabayashi ◽  
Masafumi Sakashita ◽  
Yoshimasa Imoto ◽  
Norihiko Narita ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Chronic Rhinosinusitis ◽  
Paranasal Sinuses ◽  
Eosinophilic Inflammation ◽  
Nasal Nitric Oxide

scholarly journals Agenesis of paranasal sinuses and nasal nitric oxide in primary ciliary dyskinesia

2010 ◽  
Vol 37 (3) ◽  
pp. 566-571 ◽  
Author(s):  
M. Pifferi ◽  
A. Bush ◽  
D. Caramella ◽  
M. Di Cicco ◽  
M. Zangani ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Paranasal Sinuses ◽  
Primary Ciliary Dyskinesia ◽  
Nasal Nitric Oxide ◽  
Ciliary Dyskinesia

Washout of 133-Xenon as an Objective Assessment of Paranasal Sinus Ventilation in Endoscopic Sinus Surgery

2002 ◽  
Vol 111 (8) ◽  
pp. 710-717 ◽  
Author(s):  
BO Paulsson ◽  
Sven Lindberg ◽  
Per Ohlin
Keyword(s):  
Nitric Oxide ◽  
Paranasal Sinus ◽  
Paranasal Sinuses ◽  
Endoscopic Sinus Surgery ◽  
Objective Assessment ◽  
Sinus Surgery ◽  
Symptom Improvement ◽  
Postoperative Evaluation ◽  
Nasal Nitric Oxide ◽  
Xenon Washout

Endoscopic sinus surgery (ESS) is today a common method for the treatment of chronic rhinosinusitis. Assessment of the results has been based mainly upon subjective evaluation, and only a few reports present objective measurements. In the present study, the 133-xenon washout technique was used for preoperative and postoperative evaluation of paranasal sinus ventilation in 12 patients selected for ESS. The postoperative half-times (T1/2) of 133-xenon washout were lower in the sinuses with abnormal preoperative half-times (T1/2), especially in the maxillary sinuses, where the postoperative T1/2 was 44 (22 to 150) minutes (median and quartiles, Q1–Q3) as compared with a preoperative T1/2 of 202 (94 to 278) minutes. The postoperative evaluation included a questionnaire and a follow-up visit with endoscopy and measurements of nasal nitric oxide. The results showed that patients who declared a marked reduction in symptoms exhibited significantly improved sinus ventilation. However, no direct correlation was found between improvement in ventilation and symptom improvement. Nine of the 12 patients showed improvement on endoscopy, and these patients also exhibited improved sinus ventilation. The postoperative nasal nitric oxide levels were within the normal range in 11 of the 12 patients; the other patient showed pathological T1/2 values for all paranasal sinuses. The 133-xenon washout technique is thus a method that can be used for objective evaluation of the ventilation of the paranasal sinuses before and after ESS procedures. However, the technique cannot be used to evaluate sinuses with totally obstructed ostia or postoperative sinuses with very wide neo-ostia, as rapid washout may lead to no activity remaining at the time of measurement.

Influence of Atopy on Exhaled and Nasal Nitric Oxide in Cystic Fibrosis Patients

2008 ◽  
Vol 1 (1) ◽  
pp. 9-12
Author(s):  
R. Chiron ◽  
I. Vachier ◽  
F. Counil ◽  
P. Godard ◽  
P. Chanez
Keyword(s):  
Nitric Oxide ◽  
Cystic Fibrosis ◽  
Nasal Nitric Oxide

R086: Nasal Nitric Oxide Greatly Increases in Humming

2006 ◽  
Vol 135 (2_suppl) ◽  
pp. P134-P134 ◽  
Author(s):  
Masanobu Imada ◽  
Satoshi Nonaka ◽  
Ryo Ota
Keyword(s):  
Nitric Oxide ◽  
Nasal Nitric Oxide

Pilot Evaluation of the Nasal Nitric Oxide Response to Humming as an Index of Osteomeatal Patency

2012 ◽  
Vol 26 (2) ◽  
pp. 123-126 ◽  
Author(s):  
Dennis J. Shusterman ◽  
Edward M. Weaver ◽  
Andrew N. Goldberg ◽  
Suzaynn F. Schick ◽  
Hofer H. Wong ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nasal Nitric Oxide
Sign in / Sign up

Export Citation Format

Share Document