Segmentation of male pelvic organs on computed tomography with a deep neural network fine-tuned by a level-set method

Abstract This paper proposes a new parametric level set method for topology optimization based on Deep Neural Network (DNN). In this method, the fully connected deep neural network is incorporated into the conventional level set methods to construct an effective approach for structural topology optimization. The implicit function of level set is described by fully connected deep neural networks. A DNN-based level set optimization method is proposed, where the Hamilton-Jacobi partial differential equations (PDEs) are transformed into parametrized ordinary differential equations (ODEs). The zero-level set of implicit function is updated through updating the weights and biases of networks. The parametrized reinitialization is applied periodically to prevent the implicit function from being too steep or too flat in the vicinity of its zero-level set. The proposed method is implemented in the framework of minimum compliance, which is a well-known benchmark for topology optimization. In practice, designers desire to have multiple design options, where they can choose a better conceptual design base on their design experience. One of the major advantages of DNN-based level set method is capable to generate diverse and competitive designs with different network architectures. Several numerical examples are presented to verify the effectiveness of proposed DNN-based level set method.

Download Full-text

Automated vessel segmentation in lung CT and CTA images via deep neural networks

Journal of X-Ray Science and Technology ◽

10.3233/xst-210955 ◽

2021 ◽

pp. 1-15

Author(s):

Wenjun Tan ◽

Luyu Zhou ◽

Xiaoshuo Li ◽

Xiaoyu Yang ◽

Yufei Chen ◽

...

Keyword(s):

Neural Network ◽

Computed Tomography ◽

Neural Networks ◽

Deep Neural Network ◽

Deep Neural Networks ◽

Vessel Segmentation ◽

Multi Scale ◽

Vascular Segmentation ◽

Study Results ◽

Lung Ct

BACKGROUND: The distribution of pulmonary vessels in computed tomography (CT) and computed tomography angiography (CTA) images of lung is important for diagnosing disease, formulating surgical plans and pulmonary research. PURPOSE: Based on the pulmonary vascular segmentation task of International Symposium on Image Computing and Digital Medicine 2020 challenge, this paper reviews 12 different pulmonary vascular segmentation algorithms of lung CT and CTA images and then objectively evaluates and compares their performances. METHODS: First, we present the annotated reference dataset of lung CT and CTA images. A subset of the dataset consisting 7,307 slices for training and 3,888 slices for testing was made available for participants. Second, by analyzing the performance comparison of different convolutional neural networks from 12 different institutions for pulmonary vascular segmentation, the reasons for some defects and improvements are summarized. The models are mainly based on U-Net, Attention, GAN, and multi-scale fusion network. The performance is measured in terms of Dice coefficient, over segmentation ratio and under segmentation rate. Finally, we discuss several proposed methods to improve the pulmonary vessel segmentation results using deep neural networks. RESULTS: By comparing with the annotated ground truth from both lung CT and CTA images, most of 12 deep neural network algorithms do an admirable job in pulmonary vascular extraction and segmentation with the dice coefficients ranging from 0.70 to 0.85. The dice coefficients for the top three algorithms are about 0.80. CONCLUSIONS: Study results show that integrating methods that consider spatial information, fuse multi-scale feature map, or have an excellent post-processing to deep neural network training and optimization process are significant for further improving the accuracy of pulmonary vascular segmentation.

Download Full-text