scholarly journals A COMPARATIVE DOSIMETRIC STUDY OF LEFT SIDED BREAST CANCER AFTER BREAST CONSERVING SURGERY WITH 3D-CRT AND VMAT

2020 ◽  
Vol 8 (11) ◽  
pp. 1088-1093
Author(s):  
F. Kouhen ◽  
◽  
H.El Gouache ◽  
M. Bensediq ◽  
K. Saadi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Conformal Radiotherapy ◽  
Breast Conserving Surgery ◽  
Left Breast ◽  
Conformity Index ◽  
Clinical Value ◽  
Three Dimensional Conformal Radiotherapy ◽  
3D Crt

Purpose: This paper aims to compare dosimetric differences based between three-dimensional conformal radiotherapy (3D-CRT), and volumetric modulated arc therapy(VMAT) techniques of radiotherapy plans for postoperative left breast cancer after breast conserving surgery. Materials and Methods: Nineteen patients with left breast cancer who had received breast conserving surgery without nodal involvement. Two separate treatment plans with an identical isocenter were created to each patient: 3D radiotherapy plan with 2 tangent isocentric beams with field-in-field technique andVMAT plan with Two duplicate sets of partial arcs. Results: The VMAT plan showed superior to PTV dose conformity index (CI), homogeneity index (HI), protection of the ipsilateral lung, and heart compared with 3D plan. However, it increases significantly dose to the contralateral breast with D mean which were 0.1±0.003 Gy and 5.31±1.04 Gy, respectively. Conclusion: VMAT greatly decreases the radiation doses delivered to the OAR with maintained therapeutic efficacy.However, further studies evaluating the clinical outcome of treatments are needed to proof the clinical value of this radiation technique.

scholarly journals Dosimetric comparison of Volumetric Modulated Arc Therapy and Three-Dimensional Conformal Radiotherapy during Post Mastectomy left chest wall Irradiation

2017 ◽  
Vol 2 (2) ◽  
Keyword(s):  
Breast Cancer ◽  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Left Lung ◽  
Conformal Radiotherapy ◽  
Breast Cancer Patients ◽  
Arc Therapy ◽  
Three Dimensional Conformal Radiotherapy ◽  
Higher Doses ◽  
3D Crt

Aims: To dosimetrically evaluate the Volumetric Modulated Arc Therapy (VMAT) technique and compare it with Three-Dimensional Conformal Radiotherapy (3D-CRT) for postmastectomy breast cancer therapy. Methods and Material: Ten consecutively treated left sided breast cancer patients were selected for this study. VMAT plans were generated from each of the patients planning CT and compared with 3D-CRT plans. Statistical analysis used: Two tailed paired t test Results: The VMAT technique provided statistically significant homogenous and conformal dose distribution with mean HI of (0.1±0.02) and mean CI of (1.1±0.06) when compared mean HI of (0.3±0.02) and mean CI of (1.7±0.2) in the 3D-CRT technique. VMAT plans showed reduced V30 of the heart (10±4.54) when compared to 3D-CRT plans (15.1±8.53). Except V30, VMAT plans resulted in higher doses to heart. The mean doses received by left lung was (17.50±6.27) and was significantly higher than that of 3D-CRT plans (10.20±3.72). VMAT plans also gave higher doses to the contralateral lung and the opposite breast. Conclusions: VMAT plans in post mastectomy breast cancers provide more homogenous and conformal plans as compared to 3DCRT plans but higher doses to normal tissues.

scholarly journals Dosimetric Comparison of Intensity-Modulated Radiotherapy, Volumetric Modulated Arc Therapy and Hybrid Three-Dimensional Conformal Radiotherapy/Intensity-Modulated Radiotherapy Techniques for Right Breast Cancer

2020 ◽  
Vol 9 (12) ◽  
pp. 3884
Author(s):  
Yi-Chi Liu ◽  
Hung-Ming Chang ◽  
Hsin-Hon Lin ◽  
Chia-Chun Lu ◽  
Lu-Han Lai
Keyword(s):  
Volumetric Modulated Arc Therapy ◽  
Three Dimensional ◽  
Intensity Modulated Radiotherapy ◽  
Conformal Radiotherapy ◽  
Whole Body ◽  
Intensity Modulated ◽  
Arc Therapy ◽  
Effective Doses ◽  
Three Dimensional Conformal Radiotherapy ◽  
3D Crt

This study aimed to compare different types of right breast cancer radiotherapy planning techniques and to estimate the whole-body effective doses and the critical organ absorbed doses. The three planning techniques are intensity-modulated radiotherapy (IMRT), volumetric modulated arc therapy (VMAT; two methods) and hybrid 3D-CRT/IMRT (three-dimensional conformal radiotherapy/intensity-modulated radiotherapy). The VMAT technique includes two methods to deliver a dose: non-continuous partial arc and continuous partial arc. A thermoluminescent dosimeter (TLD) is placed in the RANDO phantom to estimate the organ absorbed dose. Each planning technique applies 50.4 Gy prescription dose and treats critical organs, including the lung and heart. Dose-volume histogram was used to show the planning target volume (V95%), homogeneity index (HI), conformity index (CI), and other optimized indices. The estimation of whole-body effective dose was based on the International Commission on Radiation Protection (ICRP) Publication 60 and 103. The results were as follows: Continuous partial arc and non-continuous partial arc showed the best CI and HI. The heart absorbed doses in the continuous partial arc and hybrid 3D-CRT/IMRT were 0.07 ± 0.01% and 0% (V5% and V10%, respectively). The mean dose of the heart was lowest in hybrid 3D-CRT/IMRT (1.47 Gy ± 0.02). The dose in the left contralateral lung (V5%) was lowest in continuous partial arc (0%). The right ipsilateral lung average dose and V20% are lowest in continuous partial arc. Hybrid 3D-CRT/IMRT has the lowest mean dose to contralateral breast (organs at risk). The whole-body effective doses for ICRP-60 and ICRP-103 were highest in continuous partial arc (2.01 Sv ± 0.23 and 2.89 Sv ± 0.15, respectively). In conclusion, the use of VMAT with continuous arc has a lower risk of radiation pneumonia, while hybrid 3D-CRT/IMRT attain lower secondary malignancy risk and cardiovascular complications.

scholarly journals So sánh các thông số liều lượng của kỹ thuật vmat và 3d-crt trong xạ trị ung thư vú trái và hạch vùng

2020 ◽  
Author(s):  
Đình Long Nguyễn
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Volumetric Modulated Arc Therapy ◽  
Left Lung ◽  
Conformal Radiotherapy ◽  
Left Breast ◽  
Three Dimension ◽  
Breast Cancer Patients ◽  
Arc Therapy ◽  
3D Crt

COMPARISON OF DOSIMETRIC PARAMETERS OF VOLUMETRIC MODULATED ARC THERAPY AND THREE-DIMENSIONAL CONFORMAL RADIOTHERAPY FOR LEFT SIDE BREAST AND REGIONAL NODES Objective: Comparative study of dose parameters of Volumetric modulated arc therapy (VMAT) and three-dimension radiotherapy (3D-CRT) in patients after left breast surgery with radiation therapy with regional lymph nodes. Materials and Methods: Twenty-four plans of 12 left-breast cancer patients were treated with VMAT with 4 partial arc and 3D-CRT plans were added to compare each other, from 1/2018 to 3/2019 at the Vinmec TimesCity International Hospital. Results: The average coverage dose to the treatment volume (PTV) of VMAT plans is better than the 3D-CRT plan (99.10 ± 0.17 % compared to 98.7 ± 0.34 %; p = 0.01). Conformity index (CI), homogeneity index (HI) for VMAT plans also better results CI: 0.99 vs. 0.98; p = 0.26 and HI: 0.096 compared to 0.119; p = 0.02). Organs at risk, at low doses V5Gy, V10Gy VMAT plans do not avoid good doses by 3D-CRT plans: V5Gy for left lung (78.8 ± 4.6 % compared to 55.37 ± 4.38 %) and heart (77.15 ± 9.52 % compared to 19.15 ± 7.93 %) (p <0.001). However, at high doses, 3D-CRT plans are much higher than VMAT: Dose to left lung V20Gy (36.22 ± 3.9 % compared to 22.62 ± 2.43 %), V30Gy (30.6 ± 5.97 % compared to 11.77 ± 2.53 %) and V40Gy (24.73 ± 8.59 % compared to 3.63 ± 2.02 %) (P <0.001). Similarly, the cardiac arrival dose of the 3D-CRT plan is higher than that of VMAT: V20Gy (11.54 ± 5.83 % compared to 9.49 ± 6.00 %, p> 0.05), V30Gy (9.25 ± 5.56 % compared to 2.13 ± 1.89 %) and V40 Gy (7.54 ± 5.03 % compared with 0.2 ± 0.25 %). Dose to coronary arteries also decreased significantly for VMAT plans compared to 3D-CRT: V20Gy (0.8 ± 1.01 % compared to 27.29 ± 15.19 %) V30Gy (0.00 % compared to 23.09 ± 10.73 %). Conclusion: VMAT is dosimetrically superior to the 3D-CRT for left‑sided breast cancer patients with regional nodes by dose coverage to PTV and good ability to avoid heart and lung and coronary arteries than. Key words: Breast cancer, Postmastectomy radiotherapy, Three-dimension conformal radiotherapy, Volumetric modulated arc therapy.

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