Safety of hormonal contraception and intrauterine devices among women with depressive and bipolar disorders: a systematic review

Contraception ◽  
2016 ◽  
Vol 94 (6) ◽  
pp. 641-649 ◽  
Author(s):  
H. Pamela Pagano ◽  
Lauren B. Zapata ◽  
Erin N. Berry-Bibee ◽  
Kavita Nanda ◽  
Kathryn M. Curtis
2021 ◽  
Vol 11 (4) ◽  
pp. 434
Author(s):  
Delfina Janiri ◽  
Eliana Conte ◽  
Ilaria De Luca ◽  
Maria Velia Simone ◽  
Lorenzo Moccia ◽  
...  

Background: early onset is frequent in Bipolar Disorders (BDs), and it is characterised by the occurrence of mixed states (or mixed features). In this systematic review, we aimed to confirm and extend these observations by providing the prevalence rates of mixed states/features and data on associated clinical, pharmacological and psychopathological features. Methods: following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched from inception to 9 February 2021 for all studies investigating mixed states/mixed features in paediatric BD. Data were independently extracted by multiple observers. The prevalence rates of mixed states/features for each study were calculated. Results: eleven studies were included in our review, involving a total patient population of 1365 individuals. Overall, of the patients with paediatric age BD, 55.2% had mixed states/features (95% CI 40.1–70.3). Children with mixed states/features presented with high rates of comorbidities, in particular, with Attention Deficit Hyperactivity Disorder (ADHD). Evidences regarding the psychopathology and treatment response of mixed states/features are currently insufficient. Conclusions: our findings suggested that mixed states/features are extremely frequent in children and adolescents with BD and are characterised by high levels of comorbidity. Future investigations should focus on the relationship between mixed states/features and psychopathological dimensions as well as on the response to pharmacological treatment.


Contraception ◽  
2019 ◽  
Vol 100 (6) ◽  
pp. 480-483 ◽  
Author(s):  
Angeline Ti ◽  
Rebecca H. Stone ◽  
Maura Whiteman ◽  
Kathryn M. Curtis

Contraception ◽  
2013 ◽  
Vol 87 (5) ◽  
pp. 655-660 ◽  
Author(s):  
Naomi K. Tepper ◽  
Maria W. Steenland ◽  
Mary E. Gaffield ◽  
Polly A. Marchbanks ◽  
Kathryn M. Curtis

Contraception ◽  
2016 ◽  
Vol 94 (6) ◽  
pp. 725-738 ◽  
Author(s):  
Erin N. Berry-Bibee ◽  
Naomi K. Tepper ◽  
Tara C. Jatlaoui ◽  
Maura K. Whiteman ◽  
Denise J. Jamieson ◽  
...  

Contraception ◽  
2017 ◽  
Vol 95 (1) ◽  
pp. 17-39 ◽  
Author(s):  
Tara C. Jatlaoui ◽  
Halley E.M. Riley ◽  
Kathryn M. Curtis

2019 ◽  
Vol 29 (1) ◽  
pp. 76-97 ◽  
Author(s):  
C Varo ◽  
A Murru ◽  
E Salagre ◽  
E Jiménez ◽  
B Solé ◽  
...  

Author(s):  
Jane S. Sillman ◽  
Ajay K. Singh

The general internist needs to be up to date in contraception management. Each year nearly half of all pregnancies in the United States are unintended. Counseling about contraceptive options, provision of a back-up method, and information about emergency contraception can decrease the risk of unintended pregnancy. This chapter focuses on the aspects of contraception emphasized in Medical Knowledge Self-Assessment Program (MKSAP) 14: hormonal contraception, use of barrier methods, intrauterine devices, and emergency contraception.


SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A316-A316
Author(s):  
A G Bezerra ◽  
G Pires ◽  
M L Andersen ◽  
S Tufik ◽  
H Hachul

Abstract Introduction The effects of hormonal contraceptives on sleep has been matter of debate in current literature. While some articles observed a sleep promoting effect and reduced sleep disordered breathing, others have failed to detect any result or even detected a worse sleep pattern in women using hormonal contraception. As the literature has been growing on this field, a systematic review is necessary to gather and compare all the studies in a comprehensive way. Methods A bibliographic search was conducted in Pubmed, Scopus and Web of Science. Studies were selected first based on titles and abstracts, followed by full text analysis and data extraction. Only original studies evaluating women using hormonal contraception were considered eligible. Both objective and subjective sleep-related outcomes were extracted for analyzes. Individual effect size for each articles was calculated using regular or standardized mean differences and meta-analyses were conducted using a DerSimonian and Laird random effects model. Results After the bibliographic search, 1787 non-duplicated articles were included in our initial data screening. Articles sample was reduced to 114 records after abstract screening and to ten studies after full text analyses. The following sleep outcomes were eligible for meta-analysis: Pittsburgh Sleep Quality Index (PSQI - 3 studies), total time in bed (4), subjective total sleep time (4), objective total sleep time (3), sleep latency (6), sleep efficiency (6). None of them resulted in statistically significant effects of contraceptive use and the effect size ± 95% interval of confidence overlapped the zero value. Conclusion Hormonal contraceptives is not associated to any alteration in sleep patterns in women. This conclusion should be restricted to a general framework, since our sample does not allowed stratified analyses. Future studies should consider the effect of specific hormonal composition (ex.: combined vs. progestogen-only contraceptives) and administration route (contraceptive pills vs. levonorgestrel intrauterine device). Support AFIP, CAPES, CNPq


2020 ◽  
Vol 46 (1) ◽  
pp. 8-16 ◽  
Author(s):  
Kathryn M Curtis ◽  
Philip C Hannaford ◽  
Maria Isabel Rodriguez ◽  
Tsungai Chipato ◽  
Petrus S Steyn ◽  
...  

ObjectiveTo update a 2016 systematic review on hormonal contraception use and HIV acquisition.MethodsWe searched Pubmed and Embase between 15 January 2016 and 26 June 2019 for longitudinal studies comparing incident HIV infection among women using a hormonal contraceptive method and either non-users or users of another specific hormonal contraceptive method. We extracted information from newly identified studies, assessed study quality, and updated forest plots and meta-analyses.ResultsIn addition to 31 previously included studies, five more were identified; three provided higher quality evidence. A randomised clinical trial (RCT) found no statistically significant differences in HIV risk among users of intramuscular depot medroxyprogesterone acetate (DMPA-IM), levonorgestrel implant (LNG implant) or the copper intrauterine device (Cu-IUD). An observational study found no statistically significant differences in HIV risk among women using DMPA, norethisterone enanthate (NET-EN), implants (type not specified) or Cu-IUD. Updated results from a previously included observational study continued to find a statistically significant increased HIV risk with oral contraceptives and DMPA compared with no contraceptive use, and found no association between LNG implant and HIV risk.ConclusionsHigh-quality RCT data comparing use of DMPA, LNG implant and Cu-IUD does not support previous concerns from observational studies that DMPA-IM use increases the risk of HIV acquisition. Use of other hormonal contraceptive methods (oral contraceptives, NET-EN and implants) is not associated with an increased risk of HIV acquisition.


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