scholarly journals Not Only Mania or Depression: Mixed States/Mixed Features in Paediatric Bipolar Disorders

2021 ◽  
Vol 11 (4) ◽  
pp. 434
Author(s):  
Delfina Janiri ◽  
Eliana Conte ◽  
Ilaria De Luca ◽  
Maria Velia Simone ◽  
Lorenzo Moccia ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bipolar Disorders ◽  
Prevalence Rates ◽  
Mixed States ◽  
Total Patient ◽  
Hyperactivity Disorder ◽  
Mixed Features ◽  
Paediatric Age ◽  
Meta Analyses ◽  
The Relationship

Background: early onset is frequent in Bipolar Disorders (BDs), and it is characterised by the occurrence of mixed states (or mixed features). In this systematic review, we aimed to confirm and extend these observations by providing the prevalence rates of mixed states/features and data on associated clinical, pharmacological and psychopathological features. Methods: following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we searched from inception to 9 February 2021 for all studies investigating mixed states/mixed features in paediatric BD. Data were independently extracted by multiple observers. The prevalence rates of mixed states/features for each study were calculated. Results: eleven studies were included in our review, involving a total patient population of 1365 individuals. Overall, of the patients with paediatric age BD, 55.2% had mixed states/features (95% CI 40.1–70.3). Children with mixed states/features presented with high rates of comorbidities, in particular, with Attention Deficit Hyperactivity Disorder (ADHD). Evidences regarding the psychopathology and treatment response of mixed states/features are currently insufficient. Conclusions: our findings suggested that mixed states/features are extremely frequent in children and adolescents with BD and are characterised by high levels of comorbidity. Future investigations should focus on the relationship between mixed states/features and psychopathological dimensions as well as on the response to pharmacological treatment.

scholarly journals Psychiatric Manifestations of Coeliac Disease, a Systematic Review and Meta-Analysis

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 142 ◽  
Author(s):  
Emma Clappison ◽  
Marios Hadjivassiliou ◽  
Panagiotis Zis
Keyword(s):  
Systematic Review ◽  
Eating Disorders ◽  
Coeliac Disease ◽  
Psychiatric Disorders ◽  
Meta Analysis ◽  
Hyperactivity Disorder ◽  
Increased Risk ◽  
Meta Analyses ◽  
Psychiatric Manifestations ◽  
The Relationship

Background: Coeliac disease (CD) is increasingly prevalent and is associated with both gastrointestinal (GI) and extra-intestinal manifestations. Psychiatric disorders are amongst extra-intestinal manifestations proposed. The relationship between CD and such psychiatric disorders is not well recognised or understood. Aim: The aim of this systematic review and meta-analysis was to provide a greater understanding of the existing evidence and theories surrounding psychiatric manifestations of CD. Methodology: An online literature search using PubMed was conducted, the prevalence data for both CD and psychiatric disorders was extracted from eligible articles. Meta analyses on odds ratios were also performed. Results: A total of 37 articles were included in this review. A significant increase in risk was detected for autistic spectrum disorder (OR 1.53, 95% CI 1.24–1.88, p < 0.0001), attention deficit hyperactivity disorder (OR 1.39, 95% CI 1.18–1.63, p < 0.0001), depression (OR 2.17, 95% CI 2.17–11.15, p < 0.0001), anxiety (OR 6.03, 95% CI 2.22–16.35, p < 0.0001), and eating disorders (OR 1.62, 95% CI 1.37–1.91, p < 0.00001) amongst the CD population compared to healthy controls. No significant differences were found for bipolar disorder (OR 2.35, 95% CI 2.29–19.21, p = 0.43) or schizophrenia (OR 0.46, 95% CI 0.02–10.18, p = 0.62). Conclusion: CD is associated with an increased risk of depression, anxiety, eating disorders as well as ASD and ADHD. More research is required to investigate specific biological explanations as well as any effect of gluten free diet.

scholarly journals The relationship between zinc intake and indices of cognitive function: A systematic review and meta-analyses

2013 ◽  
Vol 72 (OCE4) ◽  
Author(s):  
M. Warthon-Medina ◽  
S. Dillon ◽  
V. Hall Moran ◽  
A. L. Stammers ◽  
P. Qualter ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Function ◽  
Zinc Intake ◽  
Meta Analyses ◽  
The Relationship

scholarly journals Human Rights and Socio-Environmental Conflicts of Mining in Mexico: A Systematic Review

2022 ◽  
Vol 14 (2) ◽  
pp. 769
Author(s):  
Abraham Camacho-Garza ◽  
Otilio A. Acevedo-Sandoval ◽  
Elena Ma. Otazo-Sánchez ◽  
Alma D. Roman-Gutiérrez ◽  
Francisco Prieto-García
Keyword(s):  
Systematic Review ◽  
Human Rights ◽  
Environmental Damage ◽  
Critical Research ◽  
Environmental Conflicts ◽  
Systematic Analysis ◽  
Mining Areas ◽  
Private Interests ◽  
Meta Analyses ◽  
The Relationship

Socio-environmental conflicts are situations that exemplify human rights transgressions caused by extractive activities. These are present in developing countries where extractivism, imperialism, and colonialism paradigms prevail. In the context of Mexico, criminalization, violence, and the absence of rule of law promote these conflicts, frequently aggravated by involvement with private interests. In the last 20 years, the relationship between human rights in the mining sector and its impact on the environment has been a critical research subject. This paper aims to carry out a systematic review to analyze human rights transgressions related to the mining industry’s impact in Mexico, and identify factors causing socio-environmental conflicts. The current study shows a systematic analysis based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology. This method contributed to the collection of references that describe conflicts due to human rights transgressions and environmental damage in mining areas in Mexico. Human rights transgressions caused by mining in a Mexican context demonstrate the inability of the state to stop the increase in socio-environmental conflicts and its lack of concern towards preventing damage to the environment.

scholarly journals Prognostic value of miR-21 for prostate cancer: a systematic review and meta-analysis

2021 ◽  
Author(s):  
MY Cynthia Stafford ◽  
Colin E Willoughby ◽  
Colum P Walsh ◽  
Declan J McKenna
Keyword(s):  
Prostate Cancer ◽  
Systematic Review ◽  
Disease Progression ◽  
Poor Prognosis ◽  
Meta Analysis ◽  
Risk Groups ◽  
Cochrane Library ◽  
Clinical Biomarker ◽  
Meta Analyses ◽  
The Relationship

Elevated levels of miR-21 expression are associated with many cancers, suggesting it may be a promising clinical biomarker. In prostate cancer (PCa), however, there is still no consensus about the usefulness of miR-21 as an indicator of disease progression. This systematic review and meta-analysis was conducted to investigate the value of miR-21 expression as a prognostic measurement in PCa patients. Medline (Ovid), EMBASE, Web of Science, Scopus and Cochrane Library databases were systematically searched for relevant publications between 2010 to 2021. Studies exploring the relationship between miR-21 expression, PCa prognosis and clinicopathological factors were selected for review. Those reporting hazard ratio (HR) and 95% confidence intervals (CIs) were subject to meta-analyses. Fixed-effect models were employed to calculated pooled HRs and 95% CIs. Risk of bias in each study was assessed using QUIPS tool. Certainty of evidence in each meta-analysis was assessed using GRADE guidelines. A total of 64 studies were included in the systematic review. Of these, 11 were eligible for inclusion in meta-analysis. Meta-analyses revealed that high miR-21 expression was associated with poor prognosis: HR=1.58 (95% CI=1.19-2.09) for biochemical recurrence, MODERATE certainty; HR=1.46 (95% CI=1.06-2.01) for death, VERY LOW certainty; and HR=1.26 (95% CI=0.70-2.27) for disease progression, VERY LOW certainty. Qualitative summary revealed elevated miR-21 expression was significantly positively associated with PCa stage, Gleason score and risk groups. This systematic review and meta-analysis suggests that elevated levels of miR-21 are associated with poor prognosis in PCa patients. miR-21 expression may therefore be a useful prognostic biomarker in this disease.

scholarly journals Adolescent Sport Participation and Symptoms of Anxiety and Depression: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 42 (3) ◽  
pp. 201-218
Author(s):  
Michael J. Panza ◽  
Scott Graupensperger ◽  
Jennifer P. Agans ◽  
Isabelle Doré ◽  
Stewart A. Vella ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sport Participation ◽  
Causal Effect ◽  
Meta Analysis ◽  
Effect Sizes ◽  
Anxiety And Depression ◽  
Organized Sport ◽  
Protective Environment ◽  
Meta Analyses ◽  
The Relationship

Sport may protect against symptoms of mental disorders that are increasingly prevalent among adolescents. This systematic review explores the relationship between adolescent organized sport participation and self-reported symptoms of anxiety and depression. From 9,955 records screened, 29 unique articles were selected that included 61 effect sizes and 122,056 participants. Effects were clustered into four categories based on the operationalization of sport involvement: absence or presence of involvement, frequency of involvement, volume of involvement, and duration of participation. Results from the random-effects meta-analyses indicated that symptoms of anxiety and depression were significantly lower among sport-involved adolescents than in those not involved in sport, although this effect size was small in magnitude. Meta-regression was used to identify how age and sex explained heterogeneity in effects. Although these results do not signify a causal effect, they do support theorizing that sport participation during adolescence may be a protective environment against anxiety and depressive symptoms.

Uso de implantes dentais em pacientes com bruxismo

2021 ◽  
Vol 12 (46) ◽  
pp. 124-130
Author(s):  
Menandro dos Santos Garcia ◽  
Ricardo Jun Furuyama ◽  
Dalter Silva Favarete ◽  
Nasser Hussein Fares
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Literature Review ◽  
Dental Implant ◽  
Temporomandibular Disorders ◽  
Implant Failure ◽  
Potential Risk Factors ◽  
Occlusal Vertical Dimension ◽  
Meta Analyses ◽  
The Relationship

Dentition with severe wear in patients stricken by bruxism is a challenge due to loss of dental structure and occlusal vertical dimension and the temporomandibular implications. Bruxism is presented as a contraindication in cases of dental implants. This systematic review was carried out by examining the electronic literature available at PubMed and Google Scholar from 2010 to 2020 in Portuguese, English and Spanish languages. The review details the relationship between bruxism and dental implant failure in contrast to temporomandibular disorders, presenting the following conclusions: a) bruxism is a contributing factor to the occurrence of technical / biological complications of the dental implant and plays an important role in the failure of the dental implant; b) the anamnesis must be detailed to confirm sleep or day bruxism; c) the control of bruxism through the use of occlusal stabilization device may provide relief in the implants region and it is highly recommended. The aim of this literature review was to summarize the influences of different potential risk factors on the incidence of late dental implant failure. The protocol for this systematic review was prepared and implemented based on PRISMA guideline – Preferred Reporting Items for Systematic Reviews and Meta-Analyses.

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